PortalPublikationenNeural CAMS and their role in the development and organizati...

Neural CAMS and their role in the development and organization of myelin sheaths

Standard

Neural CAMS and their role in the development and organization of myelin sheaths. / Bartsch, Udo.

in: FRONT BIOSCI-LANDMRK, Jahrgang 8, 01.01.2003, S. d477-490.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Bartsch, U 2003, 'Neural CAMS and their role in the development and organization of myelin sheaths', FRONT BIOSCI-LANDMRK, Jg. 8, S. d477-490. https://doi.org/10.2741/1028

APA

Bartsch, U. (2003). Neural CAMS and their role in the development and organization of myelin sheaths. FRONT BIOSCI-LANDMRK, 8, d477-490. https://doi.org/10.2741/1028

Vancouver

Bartsch U. Neural CAMS and their role in the development and organization of myelin sheaths. FRONT BIOSCI-LANDMRK. 2003 Jan 1;8:d477-490. https://doi.org/10.2741/1028

Bibtex

@article{b06ae605111e47bc92bf6d9233d275a8,
title = "Neural CAMS and their role in the development and organization of myelin sheaths",
abstract = "Myelination of axons is a prerequisite for the rapid propagation of nerve impulses, and thus for the proper functioning of the nervous system. Phenotypic analysis of genetically engineered mice has provided evidence that cell adhesion molecules are critically involved in the interaction of myelin-forming glial cells with axons, the formation of regularly spaced myelin internodes along axons and the organisation of paranodes and the myelin-free gaps separating the internodes, the nodes of Ranvier. This review will focus on three members of the immunoglobulin-superfamily, the myelin-associated glycoprotein (MAG), the neural cell adhesion molecule (NCAM) and the neural adhesion molecule L1 and will discuss studies on transgenic mice that have analyzed the role of these cell adhesion molecules in the initiation of myelination, formation of structurally intact myelin sheaths and/or maintenance of myelin and axon integrity.",
keywords = "Animals, Humans, Myelin Sheath, Neural Cell Adhesion Molecules, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Udo Bartsch",
year = "2003",
month = jan,
day = "1",
doi = "10.2741/1028",
language = "English",
volume = "8",
pages = "d477--490",
journal = "FRONT BIOSCI-LANDMRK",
issn = "2768-6701",
publisher = "Frontiers in Bioscience",

}

RIS

TY - JOUR

T1 - Neural CAMS and their role in the development and organization of myelin sheaths

AU - Bartsch, Udo

PY - 2003/1/1

Y1 - 2003/1/1

N2 - Myelination of axons is a prerequisite for the rapid propagation of nerve impulses, and thus for the proper functioning of the nervous system. Phenotypic analysis of genetically engineered mice has provided evidence that cell adhesion molecules are critically involved in the interaction of myelin-forming glial cells with axons, the formation of regularly spaced myelin internodes along axons and the organisation of paranodes and the myelin-free gaps separating the internodes, the nodes of Ranvier. This review will focus on three members of the immunoglobulin-superfamily, the myelin-associated glycoprotein (MAG), the neural cell adhesion molecule (NCAM) and the neural adhesion molecule L1 and will discuss studies on transgenic mice that have analyzed the role of these cell adhesion molecules in the initiation of myelination, formation of structurally intact myelin sheaths and/or maintenance of myelin and axon integrity.

AB - Myelination of axons is a prerequisite for the rapid propagation of nerve impulses, and thus for the proper functioning of the nervous system. Phenotypic analysis of genetically engineered mice has provided evidence that cell adhesion molecules are critically involved in the interaction of myelin-forming glial cells with axons, the formation of regularly spaced myelin internodes along axons and the organisation of paranodes and the myelin-free gaps separating the internodes, the nodes of Ranvier. This review will focus on three members of the immunoglobulin-superfamily, the myelin-associated glycoprotein (MAG), the neural cell adhesion molecule (NCAM) and the neural adhesion molecule L1 and will discuss studies on transgenic mice that have analyzed the role of these cell adhesion molecules in the initiation of myelination, formation of structurally intact myelin sheaths and/or maintenance of myelin and axon integrity.

KW - Animals

KW - Humans

KW - Myelin Sheath

KW - Neural Cell Adhesion Molecules

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.2741/1028

DO - 10.2741/1028

M3 - SCORING: Review article

C2 - 12456309

VL - 8

SP - d477-490

JO - FRONT BIOSCI-LANDMRK

JF - FRONT BIOSCI-LANDMRK

SN - 2768-6701

ER -