Necrotizing lymphadenitis: Kikuchi--Fujimoto disease alias lupus lymphadenitis?

  • Jakob Cramer
  • Stefan Schmiedel
  • N G Alegre
  • Hansjörg Schäfer
  • Gerd-Dieter Burchard
  • H Merz

Abstract

Differentiation between lymphadenopathy in potentially life-threatening systemic lupus erythematosus (SLE) and self-limiting necrotizing lymphadenitis, also called Kikuchi- Fujimoto disease (KFD), is difficult. In the past, co-occurrence of SLE and KFD has been described repeatedly in case reports. Here, we report a case of necrotizing lymphadenitis, describe the clinical and histopathologic features in detail and discuss the current literature. KFD may in fact be a histopathologic characteristic of SLE supporting the hypothesis that KFD is a rare manifestation of SLE. To clarify whether KFD is the same entity as lupus lymphadenitis, more cases with SLE and lymphadenopathy should be examined in detail.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer1
ISSN0961-2033
StatusVeröffentlicht - 2010
pubmed 19933723