Near-normal values of extravascular lung water in children
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Near-normal values of extravascular lung water in children. / Nusmeier, Anneliese; Cecchetti, Corrado; Blohm, Martin; Lehman, Rick; van der Hoeven, Johannes; Lemson, Joris.
in: PEDIATR CRIT CARE ME, Jahrgang 16, Nr. 2, 02.2015, S. E28-E33.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Near-normal values of extravascular lung water in children
AU - Nusmeier, Anneliese
AU - Cecchetti, Corrado
AU - Blohm, Martin
AU - Lehman, Rick
AU - van der Hoeven, Johannes
AU - Lemson, Joris
PY - 2015/2
Y1 - 2015/2
N2 - OBJECTIVES: To define near-normal values of extravascular lung water indexed to body weight in children.DESIGN: Prospective multicenter observational study.SETTING: Medical/surgical PICUs of 5 multinational hospitals.PATIENTS: Fifty-eight children with a median age of 4 years (range 1 month to 17 year) with heterogeneous PICU admission diagnoses were included. Extravascular lung water measurements from these children were collected after resolution of their illness. Obtained values were indexed to actual body weight and height and subsequently related to age.INTERVENTIONS: None.MEASUREMENTS AND MAIN RESULTS: Extravascular lung water indexed to body weight correlated with age (r2 = 0.7) and could be categorized in three-age groups consisting of significantly different median extravascular lung water indexed to body weight values (5th-95th percentile): less than 1 year, 9-29 mL/kg; 1-5 years, 7-25 mL/kg; and 5-17 years, 5-13 mL/kg. Extravascular lung water indexed to height did not correlate to age and resulted in an age-independent near-normal value of less than 315 mL/m.CONCLUSIONS: Younger children have higher values of extravascular lung water indexed to actual body weight. Age categorized near-normal values of extravascular lung water indexed to body weight are presented for possible clinical use. Furthermore, we suggest to index extravascular lung water to height, which seems to be age independent.
AB - OBJECTIVES: To define near-normal values of extravascular lung water indexed to body weight in children.DESIGN: Prospective multicenter observational study.SETTING: Medical/surgical PICUs of 5 multinational hospitals.PATIENTS: Fifty-eight children with a median age of 4 years (range 1 month to 17 year) with heterogeneous PICU admission diagnoses were included. Extravascular lung water measurements from these children were collected after resolution of their illness. Obtained values were indexed to actual body weight and height and subsequently related to age.INTERVENTIONS: None.MEASUREMENTS AND MAIN RESULTS: Extravascular lung water indexed to body weight correlated with age (r2 = 0.7) and could be categorized in three-age groups consisting of significantly different median extravascular lung water indexed to body weight values (5th-95th percentile): less than 1 year, 9-29 mL/kg; 1-5 years, 7-25 mL/kg; and 5-17 years, 5-13 mL/kg. Extravascular lung water indexed to height did not correlate to age and resulted in an age-independent near-normal value of less than 315 mL/m.CONCLUSIONS: Younger children have higher values of extravascular lung water indexed to actual body weight. Age categorized near-normal values of extravascular lung water indexed to body weight are presented for possible clinical use. Furthermore, we suggest to index extravascular lung water to height, which seems to be age independent.
U2 - 10.1097/PCC.0000000000000312
DO - 10.1097/PCC.0000000000000312
M3 - SCORING: Journal article
C2 - 25647139
VL - 16
SP - E28-E33
JO - PEDIATR CRIT CARE ME
JF - PEDIATR CRIT CARE ME
SN - 1529-7535
IS - 2
ER -
