National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study

TY - JOUR

T1 - National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study

AU - Parisi, Rosa

AU - Iskandar, Ireny Y K

AU - Kontopantelis, Evangelos

AU - Augustin, Matthias

AU - Griffiths, Christopher E M

AU - Ashcroft, Darren M

AU - Global Psoriasis Atlas

N1 - © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2020/5/28

Y1 - 2020/5/28

N2 - OBJECTIVE: To systematically review and provide information on the incidence of psoriasis and quantify global, regional, and country specific estimates of its prevalence.DESIGN: Systematic review and meta-analysis.DATA SOURCES: Medline, Embase, Web of Science, SciELO, Korean Journal Databases, Russian Science Citation Index, WPRIM, SaudiMedLit, Informit, IndMed, and HERDIN were searched systematically from their inception dates to October 2019.METHODS: Studies were included if they reported on the incidence or prevalence of psoriasis in the general population. Incidence data were summarised descriptively, whereas bayesian hierarchical models were fitted to estimate the global, regional, and country specific prevalence of psoriasis.RESULTS: 41 164 records were identified and 168 studies met the inclusion criteria. In adults, the incidence of psoriasis varied from 30.3 per 100 000 person years (95% confidence interval 26.6 to 34.1) in Taiwan to 321.0 per 100 000 person years in Italy. The prevalence of psoriasis varied from 0.14% (95% uncertainty interval 0.05% to 0.40%) in east Asia to 1.99% (0.64% to 6.60%) in Australasia. The prevalence of psoriasis was also high in western Europe (1.92%, 1.07% to 3.46%), central Europe (1.83%, 0.62% to 5.32%), North America (1.50%, 0.63% to 3.60%), and high income southern Latin America (1.10%, 0.36% to 2.96%).CONCLUSIONS: Eighty one per cent of the countries of the world lack information on the epidemiology of psoriasis. The disease occurs more frequently in adults than in children. Psoriasis is unequally distributed across geographical regions; it is more frequent in high income countries and in regions with older populations. The estimates provided can help guide countries and the international community when making public health decisions on the appropriate management of psoriasis and assessing its natural history over time.SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42019160817.

AB - OBJECTIVE: To systematically review and provide information on the incidence of psoriasis and quantify global, regional, and country specific estimates of its prevalence.DESIGN: Systematic review and meta-analysis.DATA SOURCES: Medline, Embase, Web of Science, SciELO, Korean Journal Databases, Russian Science Citation Index, WPRIM, SaudiMedLit, Informit, IndMed, and HERDIN were searched systematically from their inception dates to October 2019.METHODS: Studies were included if they reported on the incidence or prevalence of psoriasis in the general population. Incidence data were summarised descriptively, whereas bayesian hierarchical models were fitted to estimate the global, regional, and country specific prevalence of psoriasis.RESULTS: 41 164 records were identified and 168 studies met the inclusion criteria. In adults, the incidence of psoriasis varied from 30.3 per 100 000 person years (95% confidence interval 26.6 to 34.1) in Taiwan to 321.0 per 100 000 person years in Italy. The prevalence of psoriasis varied from 0.14% (95% uncertainty interval 0.05% to 0.40%) in east Asia to 1.99% (0.64% to 6.60%) in Australasia. The prevalence of psoriasis was also high in western Europe (1.92%, 1.07% to 3.46%), central Europe (1.83%, 0.62% to 5.32%), North America (1.50%, 0.63% to 3.60%), and high income southern Latin America (1.10%, 0.36% to 2.96%).CONCLUSIONS: Eighty one per cent of the countries of the world lack information on the epidemiology of psoriasis. The disease occurs more frequently in adults than in children. Psoriasis is unequally distributed across geographical regions; it is more frequent in high income countries and in regions with older populations. The estimates provided can help guide countries and the international community when making public health decisions on the appropriate management of psoriasis and assessing its natural history over time.SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42019160817.

KW - Adult

KW - Child

KW - Global Health

KW - Humans

KW - Incidence

KW - Prevalence

KW - Psoriasis/epidemiology

U2 - 10.1136/bmj.m1590

DO - 10.1136/bmj.m1590

M3 - SCORING: Journal article

C2 - 32467098

VL - 369

SP - m1590

JO - BMJ-BRIT MED J

JF - BMJ-BRIT MED J

SN - 0959-535X

ER -