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Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen

Standard

Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen. / Friedrich, R E; Bartel-Friedrich, S; Plambeck, K; Schmelzle, R.

in: Mund Kiefer Gesichtschir, Jahrgang 2, Nr. 3, 01.05.1998, S. 118-21.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Friedrich, RE, Bartel-Friedrich, S, Plambeck, K & Schmelzle, R 1998, 'Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen', Mund Kiefer Gesichtschir, Jg. 2, Nr. 3, S. 118-21.

APA

Friedrich, R. E., Bartel-Friedrich, S., Plambeck, K., & Schmelzle, R. (1998). Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen. Mund Kiefer Gesichtschir, 2(3), 118-21.

Vancouver

Friedrich RE, Bartel-Friedrich S, Plambeck K, Schmelzle R. Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen. Mund Kiefer Gesichtschir. 1998 Mai 1;2(3):118-21.

Bibtex

@article{f15f799ef4954cba9b221a57c7d3517b,
title = "Nachweis von extrazellul{\"a}rem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen",
abstract = "AIM: To investigate the distribution of Laminin in experimental microvascular surgery.MATERIAL AND METHODS: Autografts (4 mm) of the left common carotid artery in 20 Wistar rats were harvested after 4 weeks. The specimens were investigated immunohistochemically for the demonstration and distribution of Laminin.RESULTS: The demonstration and distribution pattern of Laminin was a function of the accuracy of each single suture. In the intima, the organisation and amount of Laminin was directed to the lumen and dependent from the distance and vitality of the vessel segments' cells. The media had in its axis direction the lowest reparative potency to regenerate the continuity break. The adventitia formed a thick cuff around the anastomosis, which was circularly grown through with Laminin-positive vasa vasorum. The marked myointimal hyperplasia in the area around the anastomosis and in the entire autograft was constituted of Laminin-positive extracellular matrix.CONCLUSIONS: Our results support the demand for a careful and atraumatic suture technique in microvascular surgery.",
keywords = "Anastomosis, Surgical, Animals, Carotid Artery, Common, Cicatrix, Laminin, Microsurgery, Muscle, Smooth, Vascular, Rats, Rats, Wistar, Wound Healing",
author = "Friedrich, {R E} and S Bartel-Friedrich and K Plambeck and R Schmelzle",
year = "1998",
month = may,
day = "1",
language = "Deutsch",
volume = "2",
pages = "118--21",
number = "3",

}

RIS

TY - JOUR

T1 - Nachweis von extrazellulärem Matrixprotein (Laminin) in experimentellen arteriellen Anastomosen

AU - Friedrich, R E

AU - Bartel-Friedrich, S

AU - Plambeck, K

AU - Schmelzle, R

PY - 1998/5/1

Y1 - 1998/5/1

N2 - AIM: To investigate the distribution of Laminin in experimental microvascular surgery.MATERIAL AND METHODS: Autografts (4 mm) of the left common carotid artery in 20 Wistar rats were harvested after 4 weeks. The specimens were investigated immunohistochemically for the demonstration and distribution of Laminin.RESULTS: The demonstration and distribution pattern of Laminin was a function of the accuracy of each single suture. In the intima, the organisation and amount of Laminin was directed to the lumen and dependent from the distance and vitality of the vessel segments' cells. The media had in its axis direction the lowest reparative potency to regenerate the continuity break. The adventitia formed a thick cuff around the anastomosis, which was circularly grown through with Laminin-positive vasa vasorum. The marked myointimal hyperplasia in the area around the anastomosis and in the entire autograft was constituted of Laminin-positive extracellular matrix.CONCLUSIONS: Our results support the demand for a careful and atraumatic suture technique in microvascular surgery.

AB - AIM: To investigate the distribution of Laminin in experimental microvascular surgery.MATERIAL AND METHODS: Autografts (4 mm) of the left common carotid artery in 20 Wistar rats were harvested after 4 weeks. The specimens were investigated immunohistochemically for the demonstration and distribution of Laminin.RESULTS: The demonstration and distribution pattern of Laminin was a function of the accuracy of each single suture. In the intima, the organisation and amount of Laminin was directed to the lumen and dependent from the distance and vitality of the vessel segments' cells. The media had in its axis direction the lowest reparative potency to regenerate the continuity break. The adventitia formed a thick cuff around the anastomosis, which was circularly grown through with Laminin-positive vasa vasorum. The marked myointimal hyperplasia in the area around the anastomosis and in the entire autograft was constituted of Laminin-positive extracellular matrix.CONCLUSIONS: Our results support the demand for a careful and atraumatic suture technique in microvascular surgery.

KW - Anastomosis, Surgical

KW - Animals

KW - Carotid Artery, Common

KW - Cicatrix

KW - Laminin

KW - Microsurgery

KW - Muscle, Smooth, Vascular

KW - Rats

KW - Rats, Wistar

KW - Wound Healing

M3 - SCORING: Zeitschriftenaufsatz

C2 - 9658799

VL - 2

SP - 118

EP - 121

IS - 3

ER -