Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing.

  • Rainer D Will
  • Matthias Eden
  • Steffen Just
  • Arne Hansen
  • Alexandra Eder
  • Derk Frank
  • Christian Kuhn
  • Thalia S Seeger
  • Ulrike Oehl
  • Stefan Wiemann
  • Bernhard Korn
  • Manfred Koegl
  • Wolfgang Rottbauer
  • Thomas Eschenhagen
  • Hugo A Katus
  • Norbert Frey

Abstract

The M-band represents a transverse structure in the center of the sarcomeric A-band and provides an anchor for the myosin-containing thick filaments. In contrast to other sarcomeric structures, eg, the Z-disc, only few M-band-specific proteins have been identified to date, and its exact molecular composition remains unclear.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer10
ISSN0009-7330
StatusVeröffentlicht - 2010
pubmed 20847312