PortalPublikationenMuscle action potential scans and ultrasound imaging in neur...

Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2

Standard

Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2. / Farschtschi, Said; Gelderblom, Mathias; Buschbaum, Sabriena; Bostock, Hugh; Grafe, Peter; Mautner, Victor F.

in: MUSCLE NERVE, Jahrgang 55, Nr. 3, 03.2017, S. 350-358.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Farschtschi, S, Gelderblom, M, Buschbaum, S, Bostock, H, Grafe, P & Mautner, VF 2017, 'Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2', MUSCLE NERVE, Jg. 55, Nr. 3, S. 350-358. https://doi.org/10.1002/mus.25256

APA

Farschtschi, S., Gelderblom, M., Buschbaum, S., Bostock, H., Grafe, P., & Mautner, V. F. (2017). Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2. MUSCLE NERVE, 55(3), 350-358. https://doi.org/10.1002/mus.25256

Vancouver

Farschtschi S, Gelderblom M, Buschbaum S, Bostock H, Grafe P, Mautner VF. Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2. MUSCLE NERVE. 2017 Mär;55(3):350-358. https://doi.org/10.1002/mus.25256

Bibtex

@article{58d7583cb6ee48d4bc848bc24badfc3b,
title = "Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2",
abstract = "INTRODUCTION: The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and to follow-up. This study compared 3 methods which may help to assess motor axon pathology in NF2 patients.METHODS: Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates (MUNE) from compound muscle action potential (CMAP) scans and by high resolution ultrasound (US) peripheral nerve imaging.RESULTS: CMAP amplitudes and nerve conduction velocity were normal in the vast majority of affected individuals, but CMAP scan MUNE revealed denervation and reinnervation in many peripheral nerves. In addition, US nerve imaging enabled monitoring of the size and number of schwannoma-like fascicular enlargements in median nerve trunks.CONCLUSION: In contrast to conventional nerve conduction studies, CMAP scan MUNE in combination with US nerve imaging can quantify the NF2-associated neuropathy and may help to monitor disease progression and drug treatments. This article is protected by copyright. All rights reserved.",
author = "Said Farschtschi and Mathias Gelderblom and Sabriena Buschbaum and Hugh Bostock and Peter Grafe and Mautner, {Victor F}",
note = "{\textcopyright} 2016 Wiley Periodicals, Inc.",
year = "2017",
month = mar,
doi = "10.1002/mus.25256",
language = "English",
volume = "55",
pages = "350--358",
journal = "MUSCLE NERVE",
issn = "0148-639X",
publisher = "John Wiley and Sons Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2

AU - Farschtschi, Said

AU - Gelderblom, Mathias

AU - Buschbaum, Sabriena

AU - Bostock, Hugh

AU - Grafe, Peter

AU - Mautner, Victor F

N1 - © 2016 Wiley Periodicals, Inc.

PY - 2017/3

Y1 - 2017/3

N2 - INTRODUCTION: The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and to follow-up. This study compared 3 methods which may help to assess motor axon pathology in NF2 patients.METHODS: Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates (MUNE) from compound muscle action potential (CMAP) scans and by high resolution ultrasound (US) peripheral nerve imaging.RESULTS: CMAP amplitudes and nerve conduction velocity were normal in the vast majority of affected individuals, but CMAP scan MUNE revealed denervation and reinnervation in many peripheral nerves. In addition, US nerve imaging enabled monitoring of the size and number of schwannoma-like fascicular enlargements in median nerve trunks.CONCLUSION: In contrast to conventional nerve conduction studies, CMAP scan MUNE in combination with US nerve imaging can quantify the NF2-associated neuropathy and may help to monitor disease progression and drug treatments. This article is protected by copyright. All rights reserved.

AB - INTRODUCTION: The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and to follow-up. This study compared 3 methods which may help to assess motor axon pathology in NF2 patients.METHODS: Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates (MUNE) from compound muscle action potential (CMAP) scans and by high resolution ultrasound (US) peripheral nerve imaging.RESULTS: CMAP amplitudes and nerve conduction velocity were normal in the vast majority of affected individuals, but CMAP scan MUNE revealed denervation and reinnervation in many peripheral nerves. In addition, US nerve imaging enabled monitoring of the size and number of schwannoma-like fascicular enlargements in median nerve trunks.CONCLUSION: In contrast to conventional nerve conduction studies, CMAP scan MUNE in combination with US nerve imaging can quantify the NF2-associated neuropathy and may help to monitor disease progression and drug treatments. This article is protected by copyright. All rights reserved.

U2 - 10.1002/mus.25256

DO - 10.1002/mus.25256

M3 - SCORING: Journal article

C2 - 27422240

VL - 55

SP - 350

EP - 358

JO - MUSCLE NERVE

JF - MUSCLE NERVE

SN - 0148-639X

IS - 3

ER -