Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
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Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research. / Hahn, Jan; Moritz, Manuela; Walter, Anton; Wieck, Tamara; Moustafa, Ayham; Mansour, Wael Yassin; Harms, Charlotte; Stenzel, Peter; Heeren, Jörg; Haider, Marie-Therese; Lange, Tobias; Schlüter, Hartmut.
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII: 29-31 January 2024, San Francisco, California, United States. Hrsg. / Attila Tárnok; Jessica P. Houston. 1. Aufl. Bellingham, Washington : SPIE , 2024. 128460C (Proceedings of SPIE; Band 12846).Publikationen: SCORING: Beitrag in Buch/Sammelwerk › Konferenzbeitrag - Aufsatz in Konferenzband › Forschung › Begutachtung
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T1 - Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
AU - Hahn, Jan
AU - Moritz, Manuela
AU - Walter, Anton
AU - Wieck, Tamara
AU - Moustafa, Ayham
AU - Mansour, Wael Yassin
AU - Harms, Charlotte
AU - Stenzel, Peter
AU - Heeren, Jörg
AU - Haider, Marie-Therese
AU - Lange, Tobias
AU - Schlüter, Hartmut
PY - 2024
Y1 - 2024
N2 - We demonstrate an early-stage prototype of an image-guided laser ablation system for precise 3D sampling of fresh-frozen tissue samples for subsequent analysis of biomolecules. Utilizing an integrated reflected light microscope and optical coherence tomography, pre-recorded image data (e.g. of characterized tissue slices) can be registered and mapped to the coordinate system for precise aiming and ablation. With this system, we are analyzing a variety of tissue samples from our many collaborators at the University Cancer Center Hamburg (UCCH) for cancer research and demonstrate the system’s feasibility through initial use cases.
AB - We demonstrate an early-stage prototype of an image-guided laser ablation system for precise 3D sampling of fresh-frozen tissue samples for subsequent analysis of biomolecules. Utilizing an integrated reflected light microscope and optical coherence tomography, pre-recorded image data (e.g. of characterized tissue slices) can be registered and mapped to the coordinate system for precise aiming and ablation. With this system, we are analyzing a variety of tissue samples from our many collaborators at the University Cancer Center Hamburg (UCCH) for cancer research and demonstrate the system’s feasibility through initial use cases.
UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12846/3003707/Multimodal-image-guided-laser-ablation-system-for-precise-3D-tissue/10.1117/12.3003707.short?tab=ArticleLinkCited
U2 - 10.1117/12.3003707
DO - 10.1117/12.3003707
M3 - Conference contribution - Article for conference
SN - 978-1-5106-6951-2
T3 - Proceedings of SPIE
BT - Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII
A2 - Tárnok, Attila
A2 - Houston, Jessica P.
PB - SPIE
CY - Bellingham, Washington
ER -