Möglichkeiten und Grenzen der Fluoreszenzdiagnostik und photodynamischen Therapie
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Möglichkeiten und Grenzen der Fluoreszenzdiagnostik und photodynamischen Therapie : Teil 2: Photodynamische Therapie. / Betz, C S; Leunig, A.
in: HNO, Jahrgang 52, Nr. 2, 02.2004, S. 175-192.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Möglichkeiten und Grenzen der Fluoreszenzdiagnostik und photodynamischen Therapie
T2 - Teil 2: Photodynamische Therapie
AU - Betz, C S
AU - Leunig, A
PY - 2004/2
Y1 - 2004/2
N2 - In photodynamic therapy, neoplastic tissue is damaged and subsequently killed by the targeted illumination of previously photosensitized cells. This review is aimed at a comprehensive, but still easily understandable, presentation of all of the aspects of these methods relevant to ENT-doctors. Initially, an explanation of the clinically relevant difficulties in the therapy of (pre-)malignant lesions of the head and neck region, a historical synopsis of the development of this method and an illustration of the biophysical basics is given. The main part of the publication, however, revolves around the description of the current status of research and a presentation of internationally approved methods. At the end, a short overview of possible future developments in this field is given.
AB - In photodynamic therapy, neoplastic tissue is damaged and subsequently killed by the targeted illumination of previously photosensitized cells. This review is aimed at a comprehensive, but still easily understandable, presentation of all of the aspects of these methods relevant to ENT-doctors. Initially, an explanation of the clinically relevant difficulties in the therapy of (pre-)malignant lesions of the head and neck region, a historical synopsis of the development of this method and an illustration of the biophysical basics is given. The main part of the publication, however, revolves around the description of the current status of research and a presentation of internationally approved methods. At the end, a short overview of possible future developments in this field is given.
KW - Cell Survival
KW - Facial Neoplasms
KW - Hematoporphyrin Photoradiation
KW - Humans
KW - Leukoplakia, Oral
KW - Mucous Membrane
KW - Neoplasm Recurrence, Local
KW - Otorhinolaryngologic Neoplasms
KW - Papilloma
KW - Photochemotherapy
KW - Photosensitivity Disorders
KW - Precancerous Conditions
KW - Skin
KW - Treatment Outcome
KW - English Abstract
KW - Journal Article
U2 - 10.1007/s00106-003-1029-1
DO - 10.1007/s00106-003-1029-1
M3 - SCORING: Zeitschriftenaufsatz
C2 - 15049331
VL - 52
SP - 175
EP - 192
JO - HNO
JF - HNO
SN - 0017-6192
IS - 2
ER -