Mitochondrial DNA variation in Sub-Saharan Africa
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Mitochondrial DNA variation in Sub-Saharan Africa : Forensic data from a mixed West African sample, Côte d'Ivoire (Ivory Coast), and Rwanda. / Göbel, Tanja M K; Bodner, Martin; Robino, Carlo; Augustin, Christa; Huber, Gabriela E; Marra, Michele; Mutesa, Léon; Pasino, Serena; Santovito, Alfredo; Zimmermann, Bettina; Schneider, Peter M; Parson, Walther.
in: FORENSIC SCI INT-GEN, Jahrgang 44, 01.2020, S. 102202.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Mitochondrial DNA variation in Sub-Saharan Africa
T2 - Forensic data from a mixed West African sample, Côte d'Ivoire (Ivory Coast), and Rwanda
AU - Göbel, Tanja M K
AU - Bodner, Martin
AU - Robino, Carlo
AU - Augustin, Christa
AU - Huber, Gabriela E
AU - Marra, Michele
AU - Mutesa, Léon
AU - Pasino, Serena
AU - Santovito, Alfredo
AU - Zimmermann, Bettina
AU - Schneider, Peter M
AU - Parson, Walther
N1 - Copyright © 2019 Elsevier B.V. All rights reserved.
PY - 2020/1
Y1 - 2020/1
N2 - This study provides 398 novel complete mitochondrial control region sequences that augment the still underrepresented data from Africa by three datasets: a mixed West African sample set deriving from 12 countries (n = 145) and datasets from Côte d'Ivoire (Ivory Coast) (n = 100) as well as Rwanda (n = 153). The analysis of mtDNA variation and genetic comparisons with published data revealed low random match probabilities in all three datasets and typical West African and East African diversity, respectively. Genetic parameters indicate that the presented mixed West African dataset may serve as first forensic mtDNA control region database for West Africa in general. In addition, a strategy for responsible forensic application of precious mtDNA population samples potentially containing close maternal relatives is outlined. The datasets will be uploaded to the forensic mtDNA database EMPOP (https://empop.online) upon publication.
AB - This study provides 398 novel complete mitochondrial control region sequences that augment the still underrepresented data from Africa by three datasets: a mixed West African sample set deriving from 12 countries (n = 145) and datasets from Côte d'Ivoire (Ivory Coast) (n = 100) as well as Rwanda (n = 153). The analysis of mtDNA variation and genetic comparisons with published data revealed low random match probabilities in all three datasets and typical West African and East African diversity, respectively. Genetic parameters indicate that the presented mixed West African dataset may serve as first forensic mtDNA control region database for West Africa in general. In addition, a strategy for responsible forensic application of precious mtDNA population samples potentially containing close maternal relatives is outlined. The datasets will be uploaded to the forensic mtDNA database EMPOP (https://empop.online) upon publication.
U2 - 10.1016/j.fsigen.2019.102202
DO - 10.1016/j.fsigen.2019.102202
M3 - SCORING: Journal article
C2 - 31775077
VL - 44
SP - 102202
JO - FORENSIC SCI INT-GEN
JF - FORENSIC SCI INT-GEN
SN - 1872-4973
ER -