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Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.

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Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. / von Bueren, André; Bacolod, M D; Hagel, Christian; Heinimann, K; Fedier, A; Kordes, Uwe; Pietsch, T; Koster, J; Grotzer, M A; Friedman, H S; Marra, G; Kool, M; Rutkowski, Stefan.

in: BRIT J CANCER, Jahrgang 107, Nr. 8, 8, 09.10.2012, S. 1399-1408.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

von Bueren, A, Bacolod, MD, Hagel, C, Heinimann, K, Fedier, A, Kordes, U, Pietsch, T, Koster, J, Grotzer, MA, Friedman, HS, Marra, G, Kool, M & Rutkowski, S 2012, 'Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.', BRIT J CANCER, Jg. 107, Nr. 8, 8, S. 1399-1408. https://doi.org/10.1038/bjc.2012.403

APA

von Bueren, A., Bacolod, M. D., Hagel, C., Heinimann, K., Fedier, A., Kordes, U., Pietsch, T., Koster, J., Grotzer, M. A., Friedman, H. S., Marra, G., Kool, M., & Rutkowski, S. (2012). Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. BRIT J CANCER, 107(8), 1399-1408. [8]. https://doi.org/10.1038/bjc.2012.403

Vancouver

von Bueren A, Bacolod MD, Hagel C, Heinimann K, Fedier A, Kordes U et al. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. BRIT J CANCER. 2012 Okt 9;107(8):1399-1408. 8. https://doi.org/10.1038/bjc.2012.403

Bibtex

@article{374a6e5a364a4cffaa280e07ad086642,
title = "Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.",
abstract = "Tumours are responsive to temozolomide (TMZ) if they are deficient in O(6)-methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR) proficient.",
keywords = "Humans, Male, Female, Child, Child, Preschool, Cell Line, Tumor, DNA Mismatch Repair/*genetics, Drug Resistance, Neoplasm/*genetics, Adaptor Proteins, Signal Transducing/biosynthesis/*genetics, Antineoplastic Agents, Alkylating/*therapeutic use, Cerebellar Neoplasms/drug therapy/*genetics/metabolism, DNA Modification Methylases/biosynthesis/genetics, DNA Repair Enzymes/biosynthesis/genetics, Dacarbazine/*analogs & derivatives/therapeutic use, Medulloblastoma/drug therapy/*genetics/metabolism, Nuclear Proteins/biosynthesis/*genetics, O(6)-Methylguanine-DNA Methyltransferase/metabolism, Tumor Suppressor Proteins/biosynthesis/genetics, Humans, Male, Female, Child, Child, Preschool, Cell Line, Tumor, DNA Mismatch Repair/*genetics, Drug Resistance, Neoplasm/*genetics, Adaptor Proteins, Signal Transducing/biosynthesis/*genetics, Antineoplastic Agents, Alkylating/*therapeutic use, Cerebellar Neoplasms/drug therapy/*genetics/metabolism, DNA Modification Methylases/biosynthesis/genetics, DNA Repair Enzymes/biosynthesis/genetics, Dacarbazine/*analogs & derivatives/therapeutic use, Medulloblastoma/drug therapy/*genetics/metabolism, Nuclear Proteins/biosynthesis/*genetics, O(6)-Methylguanine-DNA Methyltransferase/metabolism, Tumor Suppressor Proteins/biosynthesis/genetics",
author = "{von Bueren}, Andr{\'e} and Bacolod, {M D} and Christian Hagel and K Heinimann and A Fedier and Uwe Kordes and T Pietsch and J Koster and Grotzer, {M A} and Friedman, {H S} and G Marra and M Kool and Stefan Rutkowski",
year = "2012",
month = oct,
day = "9",
doi = "10.1038/bjc.2012.403",
language = "English",
volume = "107",
pages = "1399--1408",
journal = "BRIT J CANCER",
issn = "0007-0920",
publisher = "NATURE PUBLISHING GROUP",
number = "8",

}

RIS

TY - JOUR

T1 - Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.

AU - von Bueren, André

AU - Bacolod, M D

AU - Hagel, Christian

AU - Heinimann, K

AU - Fedier, A

AU - Kordes, Uwe

AU - Pietsch, T

AU - Koster, J

AU - Grotzer, M A

AU - Friedman, H S

AU - Marra, G

AU - Kool, M

AU - Rutkowski, Stefan

PY - 2012/10/9

Y1 - 2012/10/9

N2 - Tumours are responsive to temozolomide (TMZ) if they are deficient in O(6)-methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR) proficient.

AB - Tumours are responsive to temozolomide (TMZ) if they are deficient in O(6)-methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR) proficient.

KW - Humans

KW - Male

KW - Female

KW - Child

KW - Child, Preschool

KW - Cell Line, Tumor

KW - DNA Mismatch Repair/genetics

KW - Drug Resistance, Neoplasm/genetics

KW - Adaptor Proteins, Signal Transducing/biosynthesis/genetics

KW - Antineoplastic Agents, Alkylating/therapeutic use

KW - Cerebellar Neoplasms/drug therapy/genetics/metabolism

KW - DNA Modification Methylases/biosynthesis/genetics

KW - DNA Repair Enzymes/biosynthesis/genetics

KW - Dacarbazine/analogs & derivatives/therapeutic use

KW - Medulloblastoma/drug therapy/genetics/metabolism

KW - Nuclear Proteins/biosynthesis/genetics

KW - O(6)-Methylguanine-DNA Methyltransferase/metabolism

KW - Tumor Suppressor Proteins/biosynthesis/genetics

KW - Humans

KW - Male

KW - Female

KW - Child

KW - Child, Preschool

KW - Cell Line, Tumor

KW - DNA Mismatch Repair/genetics

KW - Drug Resistance, Neoplasm/genetics

KW - Adaptor Proteins, Signal Transducing/biosynthesis/genetics

KW - Antineoplastic Agents, Alkylating/therapeutic use

KW - Cerebellar Neoplasms/drug therapy/genetics/metabolism

KW - DNA Modification Methylases/biosynthesis/genetics

KW - DNA Repair Enzymes/biosynthesis/genetics

KW - Dacarbazine/analogs & derivatives/therapeutic use

KW - Medulloblastoma/drug therapy/genetics/metabolism

KW - Nuclear Proteins/biosynthesis/genetics

KW - O(6)-Methylguanine-DNA Methyltransferase/metabolism

KW - Tumor Suppressor Proteins/biosynthesis/genetics

U2 - 10.1038/bjc.2012.403

DO - 10.1038/bjc.2012.403

M3 - SCORING: Journal article

C2 - 22976800

VL - 107

SP - 1399

EP - 1408

JO - BRIT J CANCER

JF - BRIT J CANCER

SN - 0007-0920

IS - 8

M1 - 8

ER -