Mismatch Between Cardiac Perfusion, Sympathetic Innervation, and Left Ventricular Electroanatomical Map in a Patient with Recurrent Ventricular Tachycardia
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Mismatch Between Cardiac Perfusion, Sympathetic Innervation, and Left Ventricular Electroanatomical Map in a Patient with Recurrent Ventricular Tachycardia. / Jungen, Christiane; von Gogh, Gwendolyn; Schmitt, Christiane; Kuklik, Pawel; Hoffmann, Boris; Nakajima, Kenichi; Willems, Stephan; Mester, Janos; Meyer, Christian.
in: AM J CASE REP, Jahrgang 17, 25.04.2016, S. 280-2.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Mismatch Between Cardiac Perfusion, Sympathetic Innervation, and Left Ventricular Electroanatomical Map in a Patient with Recurrent Ventricular Tachycardia
AU - Jungen, Christiane
AU - von Gogh, Gwendolyn
AU - Schmitt, Christiane
AU - Kuklik, Pawel
AU - Hoffmann, Boris
AU - Nakajima, Kenichi
AU - Willems, Stephan
AU - Mester, Janos
AU - Meyer, Christian
PY - 2016/4/25
Y1 - 2016/4/25
N2 - BACKGROUND: Regional cardiac sympathetic denervation causes electrophysiological heterogeneity and has been found to be a predictor of potentially lethal VT.CASE REPORT: We present the case of 69-year-old patient admitted with recurrent ventricular tachycardia and a history of anterior myocardial infarction. In line with Tc-99m-MIBI-SPECT perfusion imaging, electroanatomical mapping revealed extensive LV anterior scarring as detected by low-voltage areas. Surprisingly, I-123-MIBG-SPECT showed an extensive deficit of sympathetic innervation inferior (mismatch) and anterolateral (match).CONCLUSIONS: Combination of electroanatomical mapping with tomographic imaging of innervation and perfusion might improve our understanding of the neural trigger of VT after myocardial infarction or substrate-based catheter ablation.
AB - BACKGROUND: Regional cardiac sympathetic denervation causes electrophysiological heterogeneity and has been found to be a predictor of potentially lethal VT.CASE REPORT: We present the case of 69-year-old patient admitted with recurrent ventricular tachycardia and a history of anterior myocardial infarction. In line with Tc-99m-MIBI-SPECT perfusion imaging, electroanatomical mapping revealed extensive LV anterior scarring as detected by low-voltage areas. Surprisingly, I-123-MIBG-SPECT showed an extensive deficit of sympathetic innervation inferior (mismatch) and anterolateral (match).CONCLUSIONS: Combination of electroanatomical mapping with tomographic imaging of innervation and perfusion might improve our understanding of the neural trigger of VT after myocardial infarction or substrate-based catheter ablation.
KW - Aged
KW - Heart/innervation
KW - Heart Ventricles/diagnostic imaging
KW - Humans
KW - Male
KW - Myocardial Perfusion Imaging
KW - Sympathetic Nervous System/physiopathology
KW - Tachycardia, Ventricular/physiopathology
KW - Tomography, Emission-Computed, Single-Photon
U2 - 10.12659/ajcr.897412
DO - 10.12659/ajcr.897412
M3 - SCORING: Journal article
C2 - 27109542
VL - 17
SP - 280
EP - 282
JO - AM J CASE REP
JF - AM J CASE REP
SN - 1941-5923
ER -