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Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial

Standard

Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial. / Külz, Anne Katrin; Landmann, Sarah; Cludius, Barbara; Rose, Nina; Heidenreich, Thomas; Jelinek, Lena; Alsleben, Heike; Wahl, Karina; Philipsen, Alexandra; Voderholzer, Ulrich; Maier, Jonathan G; Moritz, Steffen.

in: EUR ARCH PSY CLIN N, Jahrgang 269, Nr. 2, 03.2019, S. 223-233.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Külz, AK, Landmann, S, Cludius, B, Rose, N, Heidenreich, T, Jelinek, L, Alsleben, H, Wahl, K, Philipsen, A, Voderholzer, U, Maier, JG & Moritz, S 2019, 'Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial', EUR ARCH PSY CLIN N, Jg. 269, Nr. 2, S. 223-233. https://doi.org/10.1007/s00406-018-0957-4

APA

Külz, A. K., Landmann, S., Cludius, B., Rose, N., Heidenreich, T., Jelinek, L., Alsleben, H., Wahl, K., Philipsen, A., Voderholzer, U., Maier, J. G., & Moritz, S. (2019). Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial. EUR ARCH PSY CLIN N, 269(2), 223-233. https://doi.org/10.1007/s00406-018-0957-4

Vancouver

Külz AK, Landmann S, Cludius B, Rose N, Heidenreich T, Jelinek L et al. Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial. EUR ARCH PSY CLIN N. 2019 Mär;269(2):223-233. https://doi.org/10.1007/s00406-018-0957-4

Bibtex

@article{9b56eefc1b0a47f6a97f277016dbd0e0,
title = "Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial",
abstract = "Up to one-third of individuals with obsessive-compulsive disorder (OCD) do not benefit from evidence-based psychotherapy. We examined the efficacy of mindfulness-based cognitive therapy (MBCT) as a complementary treatment option. In a prospective, bicentric, assessor-blinded, randomized, and actively controlled clinical trial, 125 patients with OCD and residual symptoms after cognitive behavioral therapy (CBT) were randomized to either an MBCT group (n = 61) or to a psychoeducational group (OCD-EP; n = 64) as an active control condition. At post-treatment, there was no significant benefit of MBCT over OCD-EP with the Yale-Brown-Obsessive-Compulsive Scale (Y-BOCS) as the primary outcome measure, but with the Obsessive-Compulsive Inventory [OCI-R; F(1, 101) = 5.679, p = .036, effect size η2partial = 0.053]. Moreover, the response rate and the improvement on secondary outcomes such as obsessive beliefs and quality of life was significantly larger in the MBCT group. Non-completion rates were below 10%. At the 6-month follow-up, OC symptoms were further improved in both groups; group differences were no longer significant. Our findings suggest that MBCT, compared to a psychoeducational program, leads to accelerated improvement of self-reported OC symptoms and secondary outcomes, but not of clinician-rated OC symptoms. In the midterm, both interventions yield similar and stable, but small improvements, suggesting that additional treatment options may be necessary.",
keywords = "Adult, Aged, Cognitive Behavioral Therapy/methods, Female, Follow-Up Studies, Humans, Male, Middle Aged, Mindfulness/methods, Obsessive-Compulsive Disorder/therapy, Outcome Assessment (Health Care), Patient Education as Topic/methods, Single-Blind Method, Young Adult",
author = "K{\"u}lz, {Anne Katrin} and Sarah Landmann and Barbara Cludius and Nina Rose and Thomas Heidenreich and Lena Jelinek and Heike Alsleben and Karina Wahl and Alexandra Philipsen and Ulrich Voderholzer and Maier, {Jonathan G} and Steffen Moritz",
year = "2019",
month = mar,
doi = "10.1007/s00406-018-0957-4",
language = "English",
volume = "269",
pages = "223--233",
journal = "EUR ARCH PSY CLIN N",
issn = "0940-1334",
publisher = "D. Steinkopff-Verlag",
number = "2",

}

RIS

TY - JOUR

T1 - Mindfulness-based cognitive therapy (MBCT) in patients with obsessive-compulsive disorder (OCD) and residual symptoms after cognitive behavioral therapy (CBT): a randomized controlled trial

AU - Külz, Anne Katrin

AU - Landmann, Sarah

AU - Cludius, Barbara

AU - Rose, Nina

AU - Heidenreich, Thomas

AU - Jelinek, Lena

AU - Alsleben, Heike

AU - Wahl, Karina

AU - Philipsen, Alexandra

AU - Voderholzer, Ulrich

AU - Maier, Jonathan G

AU - Moritz, Steffen

PY - 2019/3

Y1 - 2019/3

N2 - Up to one-third of individuals with obsessive-compulsive disorder (OCD) do not benefit from evidence-based psychotherapy. We examined the efficacy of mindfulness-based cognitive therapy (MBCT) as a complementary treatment option. In a prospective, bicentric, assessor-blinded, randomized, and actively controlled clinical trial, 125 patients with OCD and residual symptoms after cognitive behavioral therapy (CBT) were randomized to either an MBCT group (n = 61) or to a psychoeducational group (OCD-EP; n = 64) as an active control condition. At post-treatment, there was no significant benefit of MBCT over OCD-EP with the Yale-Brown-Obsessive-Compulsive Scale (Y-BOCS) as the primary outcome measure, but with the Obsessive-Compulsive Inventory [OCI-R; F(1, 101) = 5.679, p = .036, effect size η2partial = 0.053]. Moreover, the response rate and the improvement on secondary outcomes such as obsessive beliefs and quality of life was significantly larger in the MBCT group. Non-completion rates were below 10%. At the 6-month follow-up, OC symptoms were further improved in both groups; group differences were no longer significant. Our findings suggest that MBCT, compared to a psychoeducational program, leads to accelerated improvement of self-reported OC symptoms and secondary outcomes, but not of clinician-rated OC symptoms. In the midterm, both interventions yield similar and stable, but small improvements, suggesting that additional treatment options may be necessary.

AB - Up to one-third of individuals with obsessive-compulsive disorder (OCD) do not benefit from evidence-based psychotherapy. We examined the efficacy of mindfulness-based cognitive therapy (MBCT) as a complementary treatment option. In a prospective, bicentric, assessor-blinded, randomized, and actively controlled clinical trial, 125 patients with OCD and residual symptoms after cognitive behavioral therapy (CBT) were randomized to either an MBCT group (n = 61) or to a psychoeducational group (OCD-EP; n = 64) as an active control condition. At post-treatment, there was no significant benefit of MBCT over OCD-EP with the Yale-Brown-Obsessive-Compulsive Scale (Y-BOCS) as the primary outcome measure, but with the Obsessive-Compulsive Inventory [OCI-R; F(1, 101) = 5.679, p = .036, effect size η2partial = 0.053]. Moreover, the response rate and the improvement on secondary outcomes such as obsessive beliefs and quality of life was significantly larger in the MBCT group. Non-completion rates were below 10%. At the 6-month follow-up, OC symptoms were further improved in both groups; group differences were no longer significant. Our findings suggest that MBCT, compared to a psychoeducational program, leads to accelerated improvement of self-reported OC symptoms and secondary outcomes, but not of clinician-rated OC symptoms. In the midterm, both interventions yield similar and stable, but small improvements, suggesting that additional treatment options may be necessary.

KW - Adult

KW - Aged

KW - Cognitive Behavioral Therapy/methods

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Mindfulness/methods

KW - Obsessive-Compulsive Disorder/therapy

KW - Outcome Assessment (Health Care)

KW - Patient Education as Topic/methods

KW - Single-Blind Method

KW - Young Adult

U2 - 10.1007/s00406-018-0957-4

DO - 10.1007/s00406-018-0957-4

M3 - SCORING: Journal article

C2 - 30446822

VL - 269

SP - 223

EP - 233

JO - EUR ARCH PSY CLIN N

JF - EUR ARCH PSY CLIN N

SN - 0940-1334

IS - 2

ER -