Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe).
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Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe). / Luck, Tobias; Riedel-Heller, Steffi G; Kaduszkiewicz, Hanna; Bickel, Horst; Jessen, Frank; Pentzek, Michael; Wiese, Birgitt; Koelsch, Heike; Bussche van den, Hendrik; Abholz, Heinz-Harald; Moesch, Edelgard; Gorfer, Sandra; Angermeyer, Matthias C; Maier, Wolfgang; Weyerer, Siegfried.
in: DEMENT GERIATR COGN, Jahrgang 24, Nr. 4, 4, 2007, S. 307-316.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe).
AU - Luck, Tobias
AU - Riedel-Heller, Steffi G
AU - Kaduszkiewicz, Hanna
AU - Bickel, Horst
AU - Jessen, Frank
AU - Pentzek, Michael
AU - Wiese, Birgitt
AU - Koelsch, Heike
AU - Bussche van den, Hendrik
AU - Abholz, Heinz-Harald
AU - Moesch, Edelgard
AU - Gorfer, Sandra
AU - Angermeyer, Matthias C
AU - Maier, Wolfgang
AU - Weyerer, Siegfried
PY - 2007
Y1 - 2007
N2 - BACKGROUND: Although mild cognitive impairment (MCI) represents a high-risk factor for developing dementia, little is known about the prevalence of MCI among patients of general practitioners (GPs). AIMS: Estimation of age-specific prevalence for original and modified concepts of MCI and their association with sociodemographic, medical and genetic (apoE epsilon4 genotype) factors among patients of GPs. METHODS: A GP practice sample of 3,327 individuals aged 75+ was assessed by structured clinical interviews. Results: Prevalence was 15.4% (95% CI = 14.1-16.6) for original and 25.2% (95% CI = 23.7-26.7) for modified MCI. Rates increased significantly with older age. Positive associations were found for apoE epsilon4 allele, vascular diseases and depressive symptoms. CONCLUSION: MCI is frequent in elderly patients of GPs. GPs have a key position in secondary prevention and care of incipient cognitive deterioration up to the diagnosis of dementia.
AB - BACKGROUND: Although mild cognitive impairment (MCI) represents a high-risk factor for developing dementia, little is known about the prevalence of MCI among patients of general practitioners (GPs). AIMS: Estimation of age-specific prevalence for original and modified concepts of MCI and their association with sociodemographic, medical and genetic (apoE epsilon4 genotype) factors among patients of GPs. METHODS: A GP practice sample of 3,327 individuals aged 75+ was assessed by structured clinical interviews. Results: Prevalence was 15.4% (95% CI = 14.1-16.6) for original and 25.2% (95% CI = 23.7-26.7) for modified MCI. Rates increased significantly with older age. Positive associations were found for apoE epsilon4 allele, vascular diseases and depressive symptoms. CONCLUSION: MCI is frequent in elderly patients of GPs. GPs have a key position in secondary prevention and care of incipient cognitive deterioration up to the diagnosis of dementia.
M3 - SCORING: Zeitschriftenaufsatz
VL - 24
SP - 307
EP - 316
JO - DEMENT GERIATR COGN
JF - DEMENT GERIATR COGN
SN - 1420-8008
IS - 4
M1 - 4
ER -