Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy.

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Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy. / Büchner, Nikolaus J; Quack, Ivo; Woznowski, Magdalena; Stähle, Constanze; Wenzel, Ulrich; Rump, Lars C.

in: RESPIRATION, Jahrgang 82, Nr. 5, 5, 2011, S. 409-417.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{8e25747219bc437594cd9c82548b3a73,
title = "Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy.",
abstract = "Endothelial dysfunction has recently been demonstrated in obstructive sleep apnea (OSA), but the underlying mechanisms are not entirely understood. Oxidative stress is a typical feature of OSA.",
keywords = "Humans, Male, Female, Middle Aged, Prospective Studies, Blood Flow Velocity, Endothelium, Vascular/*physiopathology, Acetylcholine/administration & dosage, Ascorbic Acid/administration & dosage, Atherosclerosis/physiopathology, Capillaries/physiopathology, *Continuous Positive Airway Pressure, Forearm/blood supply, Infusions, Intra-Arterial, Microcirculation, Nitroprusside/administration & dosage, *Oxidative Stress, Plethysmography, Polysomnography, Sleep Apnea, Obstructive/complications/*physiopathology/therapy, Vascular Resistance, Vasodilator Agents/*therapeutic use, Humans, Male, Female, Middle Aged, Prospective Studies, Blood Flow Velocity, Endothelium, Vascular/*physiopathology, Acetylcholine/administration & dosage, Ascorbic Acid/administration & dosage, Atherosclerosis/physiopathology, Capillaries/physiopathology, *Continuous Positive Airway Pressure, Forearm/blood supply, Infusions, Intra-Arterial, Microcirculation, Nitroprusside/administration & dosage, *Oxidative Stress, Plethysmography, Polysomnography, Sleep Apnea, Obstructive/complications/*physiopathology/therapy, Vascular Resistance, Vasodilator Agents/*therapeutic use",
author = "B{\"u}chner, {Nikolaus J} and Ivo Quack and Magdalena Woznowski and Constanze St{\"a}hle and Ulrich Wenzel and Rump, {Lars C}",
year = "2011",
language = "English",
volume = "82",
pages = "409--417",
journal = "RESPIRATION",
issn = "0025-7931",
publisher = "S. Karger AG",
number = "5",

}

RIS

TY - JOUR

T1 - Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy.

AU - Büchner, Nikolaus J

AU - Quack, Ivo

AU - Woznowski, Magdalena

AU - Stähle, Constanze

AU - Wenzel, Ulrich

AU - Rump, Lars C

PY - 2011

Y1 - 2011

N2 - Endothelial dysfunction has recently been demonstrated in obstructive sleep apnea (OSA), but the underlying mechanisms are not entirely understood. Oxidative stress is a typical feature of OSA.

AB - Endothelial dysfunction has recently been demonstrated in obstructive sleep apnea (OSA), but the underlying mechanisms are not entirely understood. Oxidative stress is a typical feature of OSA.

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Blood Flow Velocity

KW - Endothelium, Vascular/physiopathology

KW - Acetylcholine/administration & dosage

KW - Ascorbic Acid/administration & dosage

KW - Atherosclerosis/physiopathology

KW - Capillaries/physiopathology

KW - Continuous Positive Airway Pressure

KW - Forearm/blood supply

KW - Infusions, Intra-Arterial

KW - Microcirculation

KW - Nitroprusside/administration & dosage

KW - Oxidative Stress

KW - Plethysmography

KW - Polysomnography

KW - Sleep Apnea, Obstructive/complications/physiopathology/therapy

KW - Vascular Resistance

KW - Vasodilator Agents/therapeutic use

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Blood Flow Velocity

KW - Endothelium, Vascular/physiopathology

KW - Acetylcholine/administration & dosage

KW - Ascorbic Acid/administration & dosage

KW - Atherosclerosis/physiopathology

KW - Capillaries/physiopathology

KW - Continuous Positive Airway Pressure

KW - Forearm/blood supply

KW - Infusions, Intra-Arterial

KW - Microcirculation

KW - Nitroprusside/administration & dosage

KW - Oxidative Stress

KW - Plethysmography

KW - Polysomnography

KW - Sleep Apnea, Obstructive/complications/physiopathology/therapy

KW - Vascular Resistance

KW - Vasodilator Agents/therapeutic use

M3 - SCORING: Journal article

VL - 82

SP - 409

EP - 417

JO - RESPIRATION

JF - RESPIRATION

SN - 0025-7931

IS - 5

M1 - 5

ER -