Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus.
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Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus. / Sondergaard, B C; Catalá-Lehnen, Philip; Hübner, Antje K.; Bay-Jensen, A-C; Schinke, Thorsten; Henriksen, K; Schilling, Arndt; Haberland, M; Nielsen, R H; Amling, Michael; Karsdal, M A.
in: OSTEOARTHR CARTILAGE, Jahrgang 20, Nr. 2, 2, 2012, S. 136-143.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus.
AU - Sondergaard, B C
AU - Catalá-Lehnen, Philip
AU - Hübner, Antje K.
AU - Bay-Jensen, A-C
AU - Schinke, Thorsten
AU - Henriksen, K
AU - Schilling, Arndt
AU - Haberland, M
AU - Nielsen, R H
AU - Amling, Michael
AU - Karsdal, M A
PY - 2012
Y1 - 2012
N2 - Calcitonin is well-known for its inhibitory actions on bone-resorbing osteoclasts and recently potential beneficial effects on cartilage were shown. We investigated effects of salmon calcitonin (sCT) on the articular cartilage and bone, after destabilization of the medial meniscus (DMM) in normal and sCT over-expressing mice.
AB - Calcitonin is well-known for its inhibitory actions on bone-resorbing osteoclasts and recently potential beneficial effects on cartilage were shown. We investigated effects of salmon calcitonin (sCT) on the articular cartilage and bone, after destabilization of the medial meniscus (DMM) in normal and sCT over-expressing mice.
KW - Animals
KW - Mice
KW - Mice, Inbred C57BL
KW - Phenotype
KW - Mice, Transgenic
KW - Apolipoproteins E/genetics
KW - Cartilage, Articular/pathology
KW - Arthritis, Experimental/metabolism/pathology/prevention & control
KW - Bone and Bones/pathology
KW - Calcitonin/physiology
KW - Menisci, Tibial/injuries
KW - Osteoarthritis/metabolism/pathology/prevention & control
KW - Osteoblasts/pathology
KW - Osteocalcin/blood
KW - Osteogenesis/physiology
KW - Animals
KW - Mice
KW - Mice, Inbred C57BL
KW - Phenotype
KW - Mice, Transgenic
KW - Apolipoproteins E/genetics
KW - Cartilage, Articular/pathology
KW - Arthritis, Experimental/metabolism/pathology/prevention & control
KW - Bone and Bones/pathology
KW - Calcitonin/physiology
KW - Menisci, Tibial/injuries
KW - Osteoarthritis/metabolism/pathology/prevention & control
KW - Osteoblasts/pathology
KW - Osteocalcin/blood
KW - Osteogenesis/physiology
M3 - SCORING: Journal article
VL - 20
SP - 136
EP - 143
JO - OSTEOARTHR CARTILAGE
JF - OSTEOARTHR CARTILAGE
SN - 1063-4584
IS - 2
M1 - 2
ER -