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Methadon und Levomethadon - Dosierung und Nebenwirkungen

Standard

Methadon und Levomethadon - Dosierung und Nebenwirkungen. / Schoofs, Nikola; Riemer, Thomas; Bald, Lena Karoline; Heinz, Andreas; Gallinat, Jürgen; Bermpohl, Felix; Gutwinski, Stefan.

in: PSYCHIAT PRAX, Jahrgang 41, Nr. 2, 01.03.2014, S. 82-7.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schoofs, N, Riemer, T, Bald, LK, Heinz, A, Gallinat, J, Bermpohl, F & Gutwinski, S 2014, 'Methadon und Levomethadon - Dosierung und Nebenwirkungen', PSYCHIAT PRAX, Jg. 41, Nr. 2, S. 82-7. https://doi.org/10.1055/s-0033-1349627

APA

Schoofs, N., Riemer, T., Bald, L. K., Heinz, A., Gallinat, J., Bermpohl, F., & Gutwinski, S. (2014). Methadon und Levomethadon - Dosierung und Nebenwirkungen. PSYCHIAT PRAX, 41(2), 82-7. https://doi.org/10.1055/s-0033-1349627

Vancouver

Schoofs N, Riemer T, Bald LK, Heinz A, Gallinat J, Bermpohl F et al. Methadon und Levomethadon - Dosierung und Nebenwirkungen. PSYCHIAT PRAX. 2014 Mär 1;41(2):82-7. https://doi.org/10.1055/s-0033-1349627

Bibtex

@article{58cdd3d307f3491b84315fcb05845d45,
title = "Methadon und Levomethadon - Dosierung und Nebenwirkungen",
abstract = "OBJECTIVE: The aim of our survey was to assess the dosage and the frequency of side effects in patients with opioid dependency receiving opioid maintenance therapy (OMT).METHODS: A region-wide anonymous survey was carried out in the city of Berlin. The dosage, the frequency of side effects, data on the dependence disorder and type of OMT was assessed.RESULTS: Out of all 5032 patients receiving OMT in Berlin 986 participated in the study. Of all included patients 460 were treated with methadone, 371 with levomethadone. The average dose of levomethadone was significantly higher than the dose of methadone even when adequately adjusting for differential effect sizes. In the total sample, 484 participants reported side effects. The most frequent named ones were sweating and sedation. The incidence of the side effects irritability and gastrointestinal troubles was significantly higher under OMT with levomethadone, although when an adjustment for dosage was performed.CONCLUSIONS: Levomethadone is dosed significantly higher than methadone. After an adjustment for dosage was performed, some of the specific side effects occurred more often under OMT with levomethadone. The results of our survey support the use of methadone as first line treatment for OMT.",
author = "Nikola Schoofs and Thomas Riemer and Bald, {Lena Karoline} and Andreas Heinz and J{\"u}rgen Gallinat and Felix Bermpohl and Stefan Gutwinski",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2014",
month = mar,
day = "1",
doi = "10.1055/s-0033-1349627",
language = "Deutsch",
volume = "41",
pages = "82--7",
journal = "PSYCHIAT PRAX",
issn = "0303-4259",
publisher = "Georg Thieme Verlag KG",
number = "2",

}

RIS

TY - JOUR

T1 - Methadon und Levomethadon - Dosierung und Nebenwirkungen

AU - Schoofs, Nikola

AU - Riemer, Thomas

AU - Bald, Lena Karoline

AU - Heinz, Andreas

AU - Gallinat, Jürgen

AU - Bermpohl, Felix

AU - Gutwinski, Stefan

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2014/3/1

Y1 - 2014/3/1

N2 - OBJECTIVE: The aim of our survey was to assess the dosage and the frequency of side effects in patients with opioid dependency receiving opioid maintenance therapy (OMT).METHODS: A region-wide anonymous survey was carried out in the city of Berlin. The dosage, the frequency of side effects, data on the dependence disorder and type of OMT was assessed.RESULTS: Out of all 5032 patients receiving OMT in Berlin 986 participated in the study. Of all included patients 460 were treated with methadone, 371 with levomethadone. The average dose of levomethadone was significantly higher than the dose of methadone even when adequately adjusting for differential effect sizes. In the total sample, 484 participants reported side effects. The most frequent named ones were sweating and sedation. The incidence of the side effects irritability and gastrointestinal troubles was significantly higher under OMT with levomethadone, although when an adjustment for dosage was performed.CONCLUSIONS: Levomethadone is dosed significantly higher than methadone. After an adjustment for dosage was performed, some of the specific side effects occurred more often under OMT with levomethadone. The results of our survey support the use of methadone as first line treatment for OMT.

AB - OBJECTIVE: The aim of our survey was to assess the dosage and the frequency of side effects in patients with opioid dependency receiving opioid maintenance therapy (OMT).METHODS: A region-wide anonymous survey was carried out in the city of Berlin. The dosage, the frequency of side effects, data on the dependence disorder and type of OMT was assessed.RESULTS: Out of all 5032 patients receiving OMT in Berlin 986 participated in the study. Of all included patients 460 were treated with methadone, 371 with levomethadone. The average dose of levomethadone was significantly higher than the dose of methadone even when adequately adjusting for differential effect sizes. In the total sample, 484 participants reported side effects. The most frequent named ones were sweating and sedation. The incidence of the side effects irritability and gastrointestinal troubles was significantly higher under OMT with levomethadone, although when an adjustment for dosage was performed.CONCLUSIONS: Levomethadone is dosed significantly higher than methadone. After an adjustment for dosage was performed, some of the specific side effects occurred more often under OMT with levomethadone. The results of our survey support the use of methadone as first line treatment for OMT.

U2 - 10.1055/s-0033-1349627

DO - 10.1055/s-0033-1349627

M3 - SCORING: Zeitschriftenaufsatz

C2 - 24254424

VL - 41

SP - 82

EP - 87

JO - PSYCHIAT PRAX

JF - PSYCHIAT PRAX

SN - 0303-4259

IS - 2

ER -