Mental neuropathy (numb chin syndrome) leading to diagnosis of metastatic mediastinal cancer

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Mental neuropathy (numb chin syndrome) leading to diagnosis of metastatic mediastinal cancer. / Friedrich, Reinhard E.

in: ANTICANCER RES, Jahrgang 30, Nr. 5, 01.05.2010, S. 1819-21.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{280570345b9448e1a6d5eb1b115119cf,
title = "Mental neuropathy (numb chin syndrome) leading to diagnosis of metastatic mediastinal cancer",
abstract = "Neuropathy of the mental nerve is a rare condition that demands accurate differential diagnosis. A 69-year-old male experienced progressive hypoaesthesia of the right side of the corner of the mouth and chin, associated with intermittent phases of pain. Plain radiographs and computerised tomography (CT) scans revealed the mental foramen on the top of the toothless mandible and a symmetrically depicted mandibular canal. Surgical exploration demonstrated a tumour inside the mandibular canal, not visible on radiographs. Subsequently performed CT scans revealed an extensive mediastinal tumour with metastasis to multiple lymph nodes and further metastases to the kidney and liver. Diagnosis was small-cell bronchial carcinoma (extensive disease, stage grouping II B, Marburg classification). Palliative chemotherapy was ineffective and the patient died with evidence of tumour progression. The cause of a numb chin needs to be clarified further, and the syndrome should be seriously considered, using thorough diagnosis, including the surgical revision of the affected nerve.",
keywords = "Aged, Antineoplastic Agents, Carcinoma, Chin, Disease Progression, Foreign-Body Reaction, Humans, Jaw, Male, Mediastinal Neoplasms, Neoplasm Metastasis, Palliative Care, Tomography, X-Ray Computed, Trigeminal Nerve Diseases",
author = "Friedrich, {Reinhard E}",
year = "2010",
month = may,
day = "1",
language = "English",
volume = "30",
pages = "1819--21",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "5",

}

RIS

TY - JOUR

T1 - Mental neuropathy (numb chin syndrome) leading to diagnosis of metastatic mediastinal cancer

AU - Friedrich, Reinhard E

PY - 2010/5/1

Y1 - 2010/5/1

N2 - Neuropathy of the mental nerve is a rare condition that demands accurate differential diagnosis. A 69-year-old male experienced progressive hypoaesthesia of the right side of the corner of the mouth and chin, associated with intermittent phases of pain. Plain radiographs and computerised tomography (CT) scans revealed the mental foramen on the top of the toothless mandible and a symmetrically depicted mandibular canal. Surgical exploration demonstrated a tumour inside the mandibular canal, not visible on radiographs. Subsequently performed CT scans revealed an extensive mediastinal tumour with metastasis to multiple lymph nodes and further metastases to the kidney and liver. Diagnosis was small-cell bronchial carcinoma (extensive disease, stage grouping II B, Marburg classification). Palliative chemotherapy was ineffective and the patient died with evidence of tumour progression. The cause of a numb chin needs to be clarified further, and the syndrome should be seriously considered, using thorough diagnosis, including the surgical revision of the affected nerve.

AB - Neuropathy of the mental nerve is a rare condition that demands accurate differential diagnosis. A 69-year-old male experienced progressive hypoaesthesia of the right side of the corner of the mouth and chin, associated with intermittent phases of pain. Plain radiographs and computerised tomography (CT) scans revealed the mental foramen on the top of the toothless mandible and a symmetrically depicted mandibular canal. Surgical exploration demonstrated a tumour inside the mandibular canal, not visible on radiographs. Subsequently performed CT scans revealed an extensive mediastinal tumour with metastasis to multiple lymph nodes and further metastases to the kidney and liver. Diagnosis was small-cell bronchial carcinoma (extensive disease, stage grouping II B, Marburg classification). Palliative chemotherapy was ineffective and the patient died with evidence of tumour progression. The cause of a numb chin needs to be clarified further, and the syndrome should be seriously considered, using thorough diagnosis, including the surgical revision of the affected nerve.

KW - Aged

KW - Antineoplastic Agents

KW - Carcinoma

KW - Chin

KW - Disease Progression

KW - Foreign-Body Reaction

KW - Humans

KW - Jaw

KW - Male

KW - Mediastinal Neoplasms

KW - Neoplasm Metastasis

KW - Palliative Care

KW - Tomography, X-Ray Computed

KW - Trigeminal Nerve Diseases

M3 - SCORING: Journal article

C2 - 20592385

VL - 30

SP - 1819

EP - 1821

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 5

ER -