Mechanisms and clinical implications of the placebo effect: is there a potential for the elderly? A mini-review.
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Mechanisms and clinical implications of the placebo effect: is there a potential for the elderly? A mini-review. / Bingel, Ulrike; Colloca, Luana; Vase, Lene.
in: GERONTOLOGY, Jahrgang 57, Nr. 4, 4, 2011, S. 354-363.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Mechanisms and clinical implications of the placebo effect: is there a potential for the elderly? A mini-review.
AU - Bingel, Ulrike
AU - Colloca, Luana
AU - Vase, Lene
PY - 2011
Y1 - 2011
N2 - In recent years, the placebo effect has been a topic of considerable interest both in the scientific and the clinical community. In this time, the placebo effect has evolved from being considered a nuisance in clinical and pharmacological research to becoming a neurobiological phenomenon worthy of scientific investigation in its own right. Recent research shows that placebo effects are genuine psychobiological events attributable to the overall therapeutic context, and that these effects can be robust in both laboratory and clinical settings. These psychosocially induced biochemical changes in a patient's brain and body may in turn affect the course of a disease and the response to a therapy. Here we summarize and discuss the current insights into placebo mechanisms and discuss the potentially widespread implications for research and clinical practice. Even though a systematic knowledge of placebo effects across the lifespan is lacking, we aim at highlighting specific aspects related to the care of elderly patients and those suffering from neurodegenerative diseases.
AB - In recent years, the placebo effect has been a topic of considerable interest both in the scientific and the clinical community. In this time, the placebo effect has evolved from being considered a nuisance in clinical and pharmacological research to becoming a neurobiological phenomenon worthy of scientific investigation in its own right. Recent research shows that placebo effects are genuine psychobiological events attributable to the overall therapeutic context, and that these effects can be robust in both laboratory and clinical settings. These psychosocially induced biochemical changes in a patient's brain and body may in turn affect the course of a disease and the response to a therapy. Here we summarize and discuss the current insights into placebo mechanisms and discuss the potentially widespread implications for research and clinical practice. Even though a systematic knowledge of placebo effects across the lifespan is lacking, we aim at highlighting specific aspects related to the care of elderly patients and those suffering from neurodegenerative diseases.
M3 - SCORING: Zeitschriftenaufsatz
VL - 57
SP - 354
EP - 363
JO - GERONTOLOGY
JF - GERONTOLOGY
SN - 0304-324X
IS - 4
M1 - 4
ER -
