[Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]
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[Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]. / Lücke, T; Korenke, G C; Poggenburg, I; Bentele, Karl H. P.; Das, A M; Hartmann, H.
in: Z GEBURTSH NEONATOL, Jahrgang 211, Nr. 4, 4, 2007, S. 157-161.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - [Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]
AU - Lücke, T
AU - Korenke, G C
AU - Poggenburg, I
AU - Bentele, Karl H. P.
AU - Das, A M
AU - Hartmann, H
PY - 2007
Y1 - 2007
N2 - BACKGROUND: Symptoms of Vitamin B (12) deficiency in infancy include growth retardation, regression of psychomotor development, muscular hypotonia and brain atrophy. Besides an inappropriate vegetarian diet of the infants, a vegan diet or a pernicious anaemia of the mother may lead to an insufficient vitamin B (12) supply of the child. PATIENTS AND METHODS: We report here the neurological symptoms of 4 fully breast-fed infants from mothers on vegan diet or with pernicious anaemia. DISCUSSION AND CONCLUSION: Vitamin B (12) deficiency can easily be diagnosed by detection of methylmalonic acid when measuring the organic acids in urine. Vitamin B (12) deficiency should be avoided or diagnosed as early as possible since a supplementation of mother and child can prevent neurological symptoms of the baby. Furthermore, the neurological symptoms of the infant with manifest vitamin B (12) deficiency are (partially) reversible.
AB - BACKGROUND: Symptoms of Vitamin B (12) deficiency in infancy include growth retardation, regression of psychomotor development, muscular hypotonia and brain atrophy. Besides an inappropriate vegetarian diet of the infants, a vegan diet or a pernicious anaemia of the mother may lead to an insufficient vitamin B (12) supply of the child. PATIENTS AND METHODS: We report here the neurological symptoms of 4 fully breast-fed infants from mothers on vegan diet or with pernicious anaemia. DISCUSSION AND CONCLUSION: Vitamin B (12) deficiency can easily be diagnosed by detection of methylmalonic acid when measuring the organic acids in urine. Vitamin B (12) deficiency should be avoided or diagnosed as early as possible since a supplementation of mother and child can prevent neurological symptoms of the baby. Furthermore, the neurological symptoms of the infant with manifest vitamin B (12) deficiency are (partially) reversible.
M3 - SCORING: Zeitschriftenaufsatz
VL - 211
SP - 157
EP - 161
JO - Z GEBURTSH NEONATOL
JF - Z GEBURTSH NEONATOL
SN - 0948-2393
IS - 4
M1 - 4
ER -
