Mass spectrometry-based intraoperative tumor diagnostics
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Mass spectrometry-based intraoperative tumor diagnostics. / Hänel, Lorena; Kwiatkowski, Marcel; Heikaus, Laura; Schlüter, Hartmut.
in: FUTUR SCI OA, Jahrgang 5, Nr. 3, 07.03.2019, S. FSO373.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Mass spectrometry-based intraoperative tumor diagnostics
AU - Hänel, Lorena
AU - Kwiatkowski, Marcel
AU - Heikaus, Laura
AU - Schlüter, Hartmut
PY - 2019/3/7
Y1 - 2019/3/7
N2 - In surgical oncology, decisions regarding the amount of tissue to be removed can have important consequences: the decision between preserving sufficient healthy tissue and eliminating all tumor cells is one to be made intraoperatively. This review discusses the latest technical innovations for a more accurate tumor margin localization based on mass spectrometry. Highlighting the latest mass spectrometric inventions, real-time diagnosis seems to be within reach; focusing on the intelligent knife, desorption electrospray ionization, picosecond infrared laser and MasSpec pen, the current technical status is evaluated critically concerning its scientific and medical practice.
AB - In surgical oncology, decisions regarding the amount of tissue to be removed can have important consequences: the decision between preserving sufficient healthy tissue and eliminating all tumor cells is one to be made intraoperatively. This review discusses the latest technical innovations for a more accurate tumor margin localization based on mass spectrometry. Highlighting the latest mass spectrometric inventions, real-time diagnosis seems to be within reach; focusing on the intelligent knife, desorption electrospray ionization, picosecond infrared laser and MasSpec pen, the current technical status is evaluated critically concerning its scientific and medical practice.
U2 - 10.4155/fsoa-2018-0087
DO - 10.4155/fsoa-2018-0087
M3 - SCORING: Review article
VL - 5
SP - FSO373
JO - FUTUR SCI OA
JF - FUTUR SCI OA
SN - 2056-5623
IS - 3
ER -