PortalPublikationenMarfan Syndrome and Related Heritable Thoracic Aortic Aneury...

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections

Standard

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections. / De Backer, Julie; Renard, Marjolijn; Campens, Laurence; Mosquera, Laura Muino; De Paepe, Anne; Coucke, Paul; Callewaert, Bert; Kodolitsch, Yskert von.

in: CURR PHARM DESIGN, Jahrgang 21, Nr. 28, 2015, S. 4061-4075.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

De Backer, J, Renard, M, Campens, L, Mosquera, LM, De Paepe, A, Coucke, P, Callewaert, B & Kodolitsch, YV 2015, 'Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections', CURR PHARM DESIGN, Jg. 21, Nr. 28, S. 4061-4075. https://doi.org/10.2174/1381612821666150826093152

APA

De Backer, J., Renard, M., Campens, L., Mosquera, L. M., De Paepe, A., Coucke, P., Callewaert, B., & Kodolitsch, Y. V. (2015). Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections. CURR PHARM DESIGN, 21(28), 4061-4075. https://doi.org/10.2174/1381612821666150826093152

Vancouver

De Backer J, Renard M, Campens L, Mosquera LM, De Paepe A, Coucke P et al. Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections. CURR PHARM DESIGN. 2015;21(28):4061-4075. https://doi.org/10.2174/1381612821666150826093152

Bibtex

@article{430430392ae94e9382825029738a0c11,
title = "Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections",
abstract = "In this overview we aim to address a number of recent insights and developments regarding clinical aspects, etiology, and treatment of Heritable Thoracic Aortic Disease (H-TAD). We will focus on monogenetic disorders related to aortic aneurysms. H-TADs are rare but they provide a unique basis for the study of underlying pathogenetic pathways in the complex disease process of aneurysm formation. The understanding of pathomechanisms may help us to identify medical treatment targets to improve prognosis. Among the monogenetic aneurysm disorders, Marfan syndrome is considered as a paradigm entity and many insights are derived from the study of clinical, genetic and animal models for Marfan syndrome. We will therefore first provide a detailed overview of the various aspects of Marfan syndrome after which we will give an overview of related H-TAD entities. ",
keywords = "Aneurysm, Dissecting/genetics, Animals, Aortic Aneurysm, Thoracic/genetics, Disease Models, Animal, Humans, Marfan Syndrome/complications, Prognosis",
author = "{De Backer}, Julie and Marjolijn Renard and Laurence Campens and Mosquera, {Laura Muino} and {De Paepe}, Anne and Paul Coucke and Bert Callewaert and Kodolitsch, {Yskert von}",
year = "2015",
doi = "10.2174/1381612821666150826093152",
language = "English",
volume = "21",
pages = "4061--4075",
journal = "CURR PHARM DESIGN",
issn = "1381-6128",
publisher = "Bentham Science Publishers B.V.",
number = "28",

}

RIS

TY - JOUR

T1 - Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections

AU - De Backer, Julie

AU - Renard, Marjolijn

AU - Campens, Laurence

AU - Mosquera, Laura Muino

AU - De Paepe, Anne

AU - Coucke, Paul

AU - Callewaert, Bert

AU - Kodolitsch, Yskert von

PY - 2015

Y1 - 2015

N2 - In this overview we aim to address a number of recent insights and developments regarding clinical aspects, etiology, and treatment of Heritable Thoracic Aortic Disease (H-TAD). We will focus on monogenetic disorders related to aortic aneurysms. H-TADs are rare but they provide a unique basis for the study of underlying pathogenetic pathways in the complex disease process of aneurysm formation. The understanding of pathomechanisms may help us to identify medical treatment targets to improve prognosis. Among the monogenetic aneurysm disorders, Marfan syndrome is considered as a paradigm entity and many insights are derived from the study of clinical, genetic and animal models for Marfan syndrome. We will therefore first provide a detailed overview of the various aspects of Marfan syndrome after which we will give an overview of related H-TAD entities.

AB - In this overview we aim to address a number of recent insights and developments regarding clinical aspects, etiology, and treatment of Heritable Thoracic Aortic Disease (H-TAD). We will focus on monogenetic disorders related to aortic aneurysms. H-TADs are rare but they provide a unique basis for the study of underlying pathogenetic pathways in the complex disease process of aneurysm formation. The understanding of pathomechanisms may help us to identify medical treatment targets to improve prognosis. Among the monogenetic aneurysm disorders, Marfan syndrome is considered as a paradigm entity and many insights are derived from the study of clinical, genetic and animal models for Marfan syndrome. We will therefore first provide a detailed overview of the various aspects of Marfan syndrome after which we will give an overview of related H-TAD entities.

KW - Aneurysm, Dissecting/genetics

KW - Animals

KW - Aortic Aneurysm, Thoracic/genetics

KW - Disease Models, Animal

KW - Humans

KW - Marfan Syndrome/complications

KW - Prognosis

U2 - 10.2174/1381612821666150826093152

DO - 10.2174/1381612821666150826093152

M3 - SCORING: Review article

C2 - 26306841

VL - 21

SP - 4061

EP - 4075

JO - CURR PHARM DESIGN

JF - CURR PHARM DESIGN

SN - 1381-6128

IS - 28

ER -