Mapping of atrial tachycardias after catheter ablation for atrial fibrillation: use of bi-atrial activation patterns to facilitate recognition of origin
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Mapping of atrial tachycardias after catheter ablation for atrial fibrillation: use of bi-atrial activation patterns to facilitate recognition of origin. / Steven, Daniel; Seiler, Jens; Roberts-Thomson, Kurt C; Inada, Keiichi; Stevenson, William G.
in: HEART RHYTHM, Jahrgang 7, Nr. 5, 05.2010, S. 664-672.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Mapping of atrial tachycardias after catheter ablation for atrial fibrillation: use of bi-atrial activation patterns to facilitate recognition of origin
AU - Steven, Daniel
AU - Seiler, Jens
AU - Roberts-Thomson, Kurt C
AU - Inada, Keiichi
AU - Stevenson, William G
N1 - Copyright 2010 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
PY - 2010/5
Y1 - 2010/5
N2 - BACKGROUND: Mapping and ablation of atrial tachycardias (ATs) secondary to catheter ablation of atrial fibrillation (AF) is often challenging due to the complex atrial substrate, different AT mechanisms, and potential origin not only in the left atrium (LA) but also from the right atrium (RA) and the adjacent thoracic veins.OBJECTIVE: This study sought to develop an algorithm to facilitate localization of successful ablation regions based on limited activation data from simultaneous RA and coronary sinus (CS) recordings acquired from a single 20-pole catheter.METHODS: Simultaneous lateral RA and CS atrial activation patterns (AAPs) from a 20-electrode catheter were analyzed for 155 successfully ablated ATs in 133 patients (age 58 +/- 9.6 years; 104 male [78.2%]) with prior ablation for AF. The first 125 ATs in 109 patients were analyzed retrospectively to define specific AAPs related to the location of critical AT sites as defined by effective ablation in 1 of 3 atrial regions. A classification algorithm was developed and tested retrospectively in a second blinded evaluation of the 125 previously analyzed ATs. The accuracy of the algorithm was then prospectively tested in 30 ATs in 24 patients.RESULTS: Seven different lateral RA-CS activation patterns were identified as indicating AT origin from the left lateral atrium, septum, roof, or RA, with the pattern for some regions dependent on whether conduction block was present in common atrial flutter isthmuses. The algorithm derived identified the region of effective ablation with a sensitivity of 93%, a specificity of 97%, and a positive predictive value of 80% in the blinded analysis. In the prospective series, overall accuracy was 96%.CONCLUSION: Simultaneous assessment of RA and CS activation patterns from a single RA catheter suggests the likely region of origin of ATs that emerge after AF ablation, and may therefore facilitate ablation of these complex arrhythmias.
AB - BACKGROUND: Mapping and ablation of atrial tachycardias (ATs) secondary to catheter ablation of atrial fibrillation (AF) is often challenging due to the complex atrial substrate, different AT mechanisms, and potential origin not only in the left atrium (LA) but also from the right atrium (RA) and the adjacent thoracic veins.OBJECTIVE: This study sought to develop an algorithm to facilitate localization of successful ablation regions based on limited activation data from simultaneous RA and coronary sinus (CS) recordings acquired from a single 20-pole catheter.METHODS: Simultaneous lateral RA and CS atrial activation patterns (AAPs) from a 20-electrode catheter were analyzed for 155 successfully ablated ATs in 133 patients (age 58 +/- 9.6 years; 104 male [78.2%]) with prior ablation for AF. The first 125 ATs in 109 patients were analyzed retrospectively to define specific AAPs related to the location of critical AT sites as defined by effective ablation in 1 of 3 atrial regions. A classification algorithm was developed and tested retrospectively in a second blinded evaluation of the 125 previously analyzed ATs. The accuracy of the algorithm was then prospectively tested in 30 ATs in 24 patients.RESULTS: Seven different lateral RA-CS activation patterns were identified as indicating AT origin from the left lateral atrium, septum, roof, or RA, with the pattern for some regions dependent on whether conduction block was present in common atrial flutter isthmuses. The algorithm derived identified the region of effective ablation with a sensitivity of 93%, a specificity of 97%, and a positive predictive value of 80% in the blinded analysis. In the prospective series, overall accuracy was 96%.CONCLUSION: Simultaneous assessment of RA and CS activation patterns from a single RA catheter suggests the likely region of origin of ATs that emerge after AF ablation, and may therefore facilitate ablation of these complex arrhythmias.
KW - Algorithms
KW - Atrial Fibrillation/surgery
KW - Body Surface Potential Mapping
KW - Catheter Ablation/adverse effects
KW - Coronary Sinus
KW - Electrocardiography
KW - Electrophysiology
KW - Female
KW - Heart Atria/innervation
KW - Humans
KW - Male
KW - Middle Aged
KW - Predictive Value of Tests
KW - Prospective Studies
KW - Retrospective Studies
KW - Risk Factors
KW - Sensitivity and Specificity
KW - Tachycardia, Supraventricular/diagnosis
KW - Time Factors
U2 - 10.1016/j.hrthm.2010.01.009
DO - 10.1016/j.hrthm.2010.01.009
M3 - SCORING: Journal article
C2 - 20202493
VL - 7
SP - 664
EP - 672
JO - HEART RHYTHM
JF - HEART RHYTHM
SN - 1547-5271
IS - 5
ER -