Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique.
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Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique. / Lindner, Markus; Hoeges, Simon; Meiners, Wilhelm; Wissenbach, Konrad; Smeets, Ralf; Telle, Rainer; Poprawe, Reinhart; Fischer, Horst.
in: J BIOMED MATER RES A, Jahrgang 97, Nr. 4, 4, 2011, S. 466-471.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique.
AU - Lindner, Markus
AU - Hoeges, Simon
AU - Meiners, Wilhelm
AU - Wissenbach, Konrad
AU - Smeets, Ralf
AU - Telle, Rainer
AU - Poprawe, Reinhart
AU - Fischer, Horst
PY - 2011
Y1 - 2011
N2 - The additive manufacturing technique selective laser melting (SLM) has been successfully proved to be suitable for applications in implant manufacturing. SLM is well known for metal parts and offers direct manufacturing of three-dimensional (3D) parts with high bulk density on the base of individual 3D data, including computer tomography models of anatomical structures. Furthermore, an interconnecting porous structure with defined and reproducible pore size can be integrated during the design of the 3D virtual model of the implant. The objective of this study was to develop the SLM processes for a biodegradable composite material made of ?-tricalcium phosphate (?-TCP) and poly(D, L)-lactide (PDLLA). The development of a powder composite material (?-TCP/PDLLA) suitable for the SLM process was successfully performed. The microstructure of the manufactured samples exhibit a homogeneous arrangement of ceramic and polymer. The four-point bending strength was up to 23 MPa. The X-ray diffraction (XRD) analysis of the samples confirmed ?-TCP as the only present crystalline phase and the gel permeations chromatography (GPC) analysis documented a degradation of the polymer caused by the laser process less than conventional manufacturing processes. We conclude that SLM presents a new possibility to manufacture individual biodegradable implants made of ?-TCP/PDLLA.
AB - The additive manufacturing technique selective laser melting (SLM) has been successfully proved to be suitable for applications in implant manufacturing. SLM is well known for metal parts and offers direct manufacturing of three-dimensional (3D) parts with high bulk density on the base of individual 3D data, including computer tomography models of anatomical structures. Furthermore, an interconnecting porous structure with defined and reproducible pore size can be integrated during the design of the 3D virtual model of the implant. The objective of this study was to develop the SLM processes for a biodegradable composite material made of ?-tricalcium phosphate (?-TCP) and poly(D, L)-lactide (PDLLA). The development of a powder composite material (?-TCP/PDLLA) suitable for the SLM process was successfully performed. The microstructure of the manufactured samples exhibit a homogeneous arrangement of ceramic and polymer. The four-point bending strength was up to 23 MPa. The X-ray diffraction (XRD) analysis of the samples confirmed ?-TCP as the only present crystalline phase and the gel permeations chromatography (GPC) analysis documented a degradation of the polymer caused by the laser process less than conventional manufacturing processes. We conclude that SLM presents a new possibility to manufacture individual biodegradable implants made of ?-TCP/PDLLA.
KW - Materials Testing
KW - Absorbable Implants
KW - Bone Substitutes/chemical synthesis
KW - Calcium Phosphates/pharmacology
KW - Implants, Experimental
KW - Lactic Acid/pharmacology
KW - Lasers
KW - Microscopy, Electron, Scanning
KW - Particle Size
KW - Polymers/pharmacology
KW - Porosity/drug effects
KW - Powders
KW - Surface Properties/drug effects
KW - Tissue Engineering/methods
KW - Materials Testing
KW - Absorbable Implants
KW - Bone Substitutes/chemical synthesis
KW - Calcium Phosphates/pharmacology
KW - Implants, Experimental
KW - Lactic Acid/pharmacology
KW - Lasers
KW - Microscopy, Electron, Scanning
KW - Particle Size
KW - Polymers/pharmacology
KW - Porosity/drug effects
KW - Powders
KW - Surface Properties/drug effects
KW - Tissue Engineering/methods
M3 - SCORING: Journal article
VL - 97
SP - 466
EP - 471
JO - J BIOMED MATER RES A
JF - J BIOMED MATER RES A
SN - 1549-3296
IS - 4
M1 - 4
ER -
