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Manifestation and outcome of severe malaria in children in northern Ghana.

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Manifestation and outcome of severe malaria in children in northern Ghana. / Mockenhaupt, Frank P; Ehrhardt, Stephan; Burkhardt, Jana; Bosomtwe, Samuel Y; Laryea, Stephen; Anemana, Sylvester D; Otchwemah, Rowland N; Cramer, Jakob; Dietz, Ekkehart; Gellert, Sabine; Bienzle, Ulrich.

in: AM J TROP MED HYG, Jahrgang 71, Nr. 2, 2, 2004, S. 167-172.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Mockenhaupt, FP, Ehrhardt, S, Burkhardt, J, Bosomtwe, SY, Laryea, S, Anemana, SD, Otchwemah, RN, Cramer, J, Dietz, E, Gellert, S & Bienzle, U 2004, 'Manifestation and outcome of severe malaria in children in northern Ghana.', AM J TROP MED HYG, Jg. 71, Nr. 2, 2, S. 167-172. <http://www.ncbi.nlm.nih.gov/pubmed/15306705?dopt=Citation>

APA

Mockenhaupt, F. P., Ehrhardt, S., Burkhardt, J., Bosomtwe, S. Y., Laryea, S., Anemana, S. D., Otchwemah, R. N., Cramer, J., Dietz, E., Gellert, S., & Bienzle, U. (2004). Manifestation and outcome of severe malaria in children in northern Ghana. AM J TROP MED HYG, 71(2), 167-172. [2]. http://www.ncbi.nlm.nih.gov/pubmed/15306705?dopt=Citation

Vancouver

Mockenhaupt FP, Ehrhardt S, Burkhardt J, Bosomtwe SY, Laryea S, Anemana SD et al. Manifestation and outcome of severe malaria in children in northern Ghana. AM J TROP MED HYG. 2004;71(2):167-172. 2.

Bibtex

@article{0a3f46bcd6a041f5bce77c4bca6a55b0,
title = "Manifestation and outcome of severe malaria in children in northern Ghana.",
abstract = "The symptoms of severe malaria and their contribution to mortality were assessed in 290 children in northern Ghana. Common symptoms were severe anemia (55%), prostration (33%), respiratory distress (23%), convulsions (20%), and impaired consciousness (19%). Age influenced this pattern. The fatality rate was 11.2%. In multivariate analysis, circulatory collapse, impaired consciousness, hypoglycemia, and malnutrition independently predicted death. Children with severe malaria by the current World Health Organization (WHO) classification, but not by the previous one (1990), showed relatively mild clinical manifestations and a low case fatality rate (3.2%). In hospitalized children with severe malaria in northern Ghana, severe anemia is the leading manifestation, but itself does not contribute to mortality. In this region, malnutrition and circulatory collapse were important predictors of fatal malaria. The current WHO criteria serve well in identifying life-threatening disease, but also include rather mild cases that may complicate the allocation of immediate care in settings with limited resources.",
author = "Mockenhaupt, {Frank P} and Stephan Ehrhardt and Jana Burkhardt and Bosomtwe, {Samuel Y} and Stephen Laryea and Anemana, {Sylvester D} and Otchwemah, {Rowland N} and Jakob Cramer and Ekkehart Dietz and Sabine Gellert and Ulrich Bienzle",
year = "2004",
language = "Deutsch",
volume = "71",
pages = "167--172",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

RIS

TY - JOUR

T1 - Manifestation and outcome of severe malaria in children in northern Ghana.

AU - Mockenhaupt, Frank P

AU - Ehrhardt, Stephan

AU - Burkhardt, Jana

AU - Bosomtwe, Samuel Y

AU - Laryea, Stephen

AU - Anemana, Sylvester D

AU - Otchwemah, Rowland N

AU - Cramer, Jakob

AU - Dietz, Ekkehart

AU - Gellert, Sabine

AU - Bienzle, Ulrich

PY - 2004

Y1 - 2004

N2 - The symptoms of severe malaria and their contribution to mortality were assessed in 290 children in northern Ghana. Common symptoms were severe anemia (55%), prostration (33%), respiratory distress (23%), convulsions (20%), and impaired consciousness (19%). Age influenced this pattern. The fatality rate was 11.2%. In multivariate analysis, circulatory collapse, impaired consciousness, hypoglycemia, and malnutrition independently predicted death. Children with severe malaria by the current World Health Organization (WHO) classification, but not by the previous one (1990), showed relatively mild clinical manifestations and a low case fatality rate (3.2%). In hospitalized children with severe malaria in northern Ghana, severe anemia is the leading manifestation, but itself does not contribute to mortality. In this region, malnutrition and circulatory collapse were important predictors of fatal malaria. The current WHO criteria serve well in identifying life-threatening disease, but also include rather mild cases that may complicate the allocation of immediate care in settings with limited resources.

AB - The symptoms of severe malaria and their contribution to mortality were assessed in 290 children in northern Ghana. Common symptoms were severe anemia (55%), prostration (33%), respiratory distress (23%), convulsions (20%), and impaired consciousness (19%). Age influenced this pattern. The fatality rate was 11.2%. In multivariate analysis, circulatory collapse, impaired consciousness, hypoglycemia, and malnutrition independently predicted death. Children with severe malaria by the current World Health Organization (WHO) classification, but not by the previous one (1990), showed relatively mild clinical manifestations and a low case fatality rate (3.2%). In hospitalized children with severe malaria in northern Ghana, severe anemia is the leading manifestation, but itself does not contribute to mortality. In this region, malnutrition and circulatory collapse were important predictors of fatal malaria. The current WHO criteria serve well in identifying life-threatening disease, but also include rather mild cases that may complicate the allocation of immediate care in settings with limited resources.

M3 - SCORING: Zeitschriftenaufsatz

VL - 71

SP - 167

EP - 172

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 2

M1 - 2

ER -