Management of patients with vulvar cancer: a perspective review according to tumour stage

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Management of patients with vulvar cancer: a perspective review according to tumour stage. / Woelber, Linn; Trillsch, Fabian; Kock, Lilli; Grimm, Donata; Petersen, Cordula; Choschzick, Matthias; Jänicke, Fritz; Mahner, Sven.

in: THER ADV MED ONCOL, Jahrgang 5, Nr. 3, 01.05.2013, S. 183-92.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{4b5588e316e94c0d85a3280739d4bd17,
title = "Management of patients with vulvar cancer: a perspective review according to tumour stage",
abstract = "Treatment of patients with vulvar cancer is challenging for gynaecologic oncologists. Owing to the localization in a sensitive area, surgical radicality and the indication for adjuvant treatment have to be balanced with psychosocial aspects to treat patients adequately. Clinical management is therefore highly dependent on the tumour stage. For patients with early-stage disease (FIGO I-II) therapy mainly concentrates on surgery with resection of the primary tumour and staging of the groin lymph nodes. In intermediate-stage vulvar cancer (FIGO III), advanced disease is expressed by affected inguinofemoral lymph nodes bringing radical lymphadenectomy and adjuvant therapy as well as radiation or chemoradiation into the focus of treatment. For locally advanced or metastatic vulvar cancer (FIGO IV) neoadjuvant or definitive chemoradiation has to be considered besides surgery. Owing to the low incidence of the disease, the level of evidence for different treatment modalities is poor. This review therefore puts different recommendations of clinical management in context and highlights the need for future trials.",
author = "Linn Woelber and Fabian Trillsch and Lilli Kock and Donata Grimm and Cordula Petersen and Matthias Choschzick and Fritz J{\"a}nicke and Sven Mahner",
year = "2013",
month = may,
day = "1",
doi = "10.1177/1758834012471699",
language = "English",
volume = "5",
pages = "183--92",
journal = "THER ADV MED ONCOL",
issn = "1758-8340",
publisher = "Old City Publishing",
number = "3",

}

RIS

TY - JOUR

T1 - Management of patients with vulvar cancer: a perspective review according to tumour stage

AU - Woelber, Linn

AU - Trillsch, Fabian

AU - Kock, Lilli

AU - Grimm, Donata

AU - Petersen, Cordula

AU - Choschzick, Matthias

AU - Jänicke, Fritz

AU - Mahner, Sven

PY - 2013/5/1

Y1 - 2013/5/1

N2 - Treatment of patients with vulvar cancer is challenging for gynaecologic oncologists. Owing to the localization in a sensitive area, surgical radicality and the indication for adjuvant treatment have to be balanced with psychosocial aspects to treat patients adequately. Clinical management is therefore highly dependent on the tumour stage. For patients with early-stage disease (FIGO I-II) therapy mainly concentrates on surgery with resection of the primary tumour and staging of the groin lymph nodes. In intermediate-stage vulvar cancer (FIGO III), advanced disease is expressed by affected inguinofemoral lymph nodes bringing radical lymphadenectomy and adjuvant therapy as well as radiation or chemoradiation into the focus of treatment. For locally advanced or metastatic vulvar cancer (FIGO IV) neoadjuvant or definitive chemoradiation has to be considered besides surgery. Owing to the low incidence of the disease, the level of evidence for different treatment modalities is poor. This review therefore puts different recommendations of clinical management in context and highlights the need for future trials.

AB - Treatment of patients with vulvar cancer is challenging for gynaecologic oncologists. Owing to the localization in a sensitive area, surgical radicality and the indication for adjuvant treatment have to be balanced with psychosocial aspects to treat patients adequately. Clinical management is therefore highly dependent on the tumour stage. For patients with early-stage disease (FIGO I-II) therapy mainly concentrates on surgery with resection of the primary tumour and staging of the groin lymph nodes. In intermediate-stage vulvar cancer (FIGO III), advanced disease is expressed by affected inguinofemoral lymph nodes bringing radical lymphadenectomy and adjuvant therapy as well as radiation or chemoradiation into the focus of treatment. For locally advanced or metastatic vulvar cancer (FIGO IV) neoadjuvant or definitive chemoradiation has to be considered besides surgery. Owing to the low incidence of the disease, the level of evidence for different treatment modalities is poor. This review therefore puts different recommendations of clinical management in context and highlights the need for future trials.

U2 - 10.1177/1758834012471699

DO - 10.1177/1758834012471699

M3 - SCORING: Journal article

C2 - 23634196

VL - 5

SP - 183

EP - 192

JO - THER ADV MED ONCOL

JF - THER ADV MED ONCOL

SN - 1758-8340

IS - 3

ER -