Major liver resections for primary liver malignancies in the elderly.
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Major liver resections for primary liver malignancies in the elderly. / Sgourakis, G; Sotiropoulos, G C; Bockhorn, Maximilian; Fouzas, I; Radtke, A; Molmenti, E P; Drühe, N; Broelsch, C E; Karaliotas, C; Lang, H.
in: ACTA CHIR BELG, Jahrgang 109, Nr. 3, 3, 2009, S. 340-344.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Major liver resections for primary liver malignancies in the elderly.
AU - Sgourakis, G
AU - Sotiropoulos, G C
AU - Bockhorn, Maximilian
AU - Fouzas, I
AU - Radtke, A
AU - Molmenti, E P
AU - Drühe, N
AU - Broelsch, C E
AU - Karaliotas, C
AU - Lang, H
PY - 2009
Y1 - 2009
N2 - PURPOSE: The aim of our prospective study was to assess the results of major hepatic resections for primary liver tumours in patients 75 years of age or older. METHODS: From 10/1999 to 04/2006, 23 patients with non-cirrhotic livers > or = 75 years presented to our department to undergo curative resection for primary liver malignancies. Data were collected prospectively. Patients were assigned to two groups. Group A included those with resectable tumours, while Group B was made up of those with unresectable lesions. RESULTS: Fourteen patients had intrahepatic cholangiocarcinoma while 9 had hepatocellular carcinoma. Comorbidities were present in every case. Morbidity and hospital mortality rates for group A patients were 25% and 8%, respectively. The corresponding rates for group B patients were 9% and 9%. The 1-, 2-, and 3-year cumulative group A survival was 71%, 51% and 26% for cholangiocarcinoma and 80%, 60% and 60% for hepatocellular carcinoma, respectively. The corresponding group B survival was 45%, 18% and 0%. CONCLUSION: Advanced age does not seem to negatively affect the outcome of liver resections for malignancies. Hepatic resections in patients 75 years of age or older may be carried out with relative safety as long as patients are appropriately selected.
AB - PURPOSE: The aim of our prospective study was to assess the results of major hepatic resections for primary liver tumours in patients 75 years of age or older. METHODS: From 10/1999 to 04/2006, 23 patients with non-cirrhotic livers > or = 75 years presented to our department to undergo curative resection for primary liver malignancies. Data were collected prospectively. Patients were assigned to two groups. Group A included those with resectable tumours, while Group B was made up of those with unresectable lesions. RESULTS: Fourteen patients had intrahepatic cholangiocarcinoma while 9 had hepatocellular carcinoma. Comorbidities were present in every case. Morbidity and hospital mortality rates for group A patients were 25% and 8%, respectively. The corresponding rates for group B patients were 9% and 9%. The 1-, 2-, and 3-year cumulative group A survival was 71%, 51% and 26% for cholangiocarcinoma and 80%, 60% and 60% for hepatocellular carcinoma, respectively. The corresponding group B survival was 45%, 18% and 0%. CONCLUSION: Advanced age does not seem to negatively affect the outcome of liver resections for malignancies. Hepatic resections in patients 75 years of age or older may be carried out with relative safety as long as patients are appropriately selected.
KW - Humans
KW - Male
KW - Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Age Factors
KW - Survival Rate
KW - Follow-Up Studies
KW - Retrospective Studies
KW - Bile Duct Neoplasms mortality
KW - Bile Ducts, Intrahepatic
KW - Carcinoma, Hepatocellular mortality
KW - Cholangiocarcinoma mortality
KW - Greece epidemiology
KW - Hepatectomy methods
KW - Liver Neoplasms mortality
KW - Humans
KW - Male
KW - Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Age Factors
KW - Survival Rate
KW - Follow-Up Studies
KW - Retrospective Studies
KW - Bile Duct Neoplasms mortality
KW - Bile Ducts, Intrahepatic
KW - Carcinoma, Hepatocellular mortality
KW - Cholangiocarcinoma mortality
KW - Greece epidemiology
KW - Hepatectomy methods
KW - Liver Neoplasms mortality
M3 - SCORING: Zeitschriftenaufsatz
VL - 109
SP - 340
EP - 344
JO - ACTA CHIR BELG
JF - ACTA CHIR BELG
SN - 0001-5458
IS - 3
M1 - 3
ER -
