Maintaining success, reducing treatment burden, focusing on survivorship: highlights from the third European consensus conference on diagnosis and treatment of germ-cell cancer.

TY - JOUR

T1 - Maintaining success, reducing treatment burden, focusing on survivorship: highlights from the third European consensus conference on diagnosis and treatment of germ-cell cancer.

AU - Beyer, J

AU - Albers, P

AU - Altena, R

AU - Aparicio, J

AU - Bokemeyer, C

AU - Busch, J

AU - Cathomas, R

AU - Cavallin-Stahl, E

AU - Clarke, N W

AU - Claßen, J

AU - Cohn-Cedermark, G

AU - Dahl, A A

AU - Daugaard, G

AU - De Giorgi, U

AU - De Santis, M

AU - De Wit, M

AU - De Wit, R

AU - Dieckmann, K P

AU - Fenner, M

AU - Fizazi, K

AU - Flechon, A

AU - Fossa, S D

AU - Germá Lluch, J R

AU - Gietema, J A

AU - Gillessen, S

AU - Giwercman, A

AU - Hartmann, J T

AU - Heidenreich, A

AU - Hentrich, M

AU - Honecker, F

AU - Horwich, A

AU - Huddart, R A

AU - Kliesch, S

AU - Kollmannsberger, C

AU - Krege, S

AU - Laguna, M P

AU - Looijenga, L H J

AU - Lorch, A

AU - Lotz, J P

AU - Mayer, F

AU - Necchi, A

AU - Nicolai, N

AU - Nuver, J

AU - Oechsle, K

AU - Oldenburg, J

AU - Oosterhuis, J W

AU - Powles, T

AU - Rajpert-De Meyts, E

AU - Rick, O

AU - Rosti, G

AU - Salvioni, R

AU - Schrader, M

AU - Schweyer, S

AU - Sedlmayer, F

AU - Sohaib, A

AU - Souchon, R

AU - Tandstad, T

AU - Winter, C

AU - Wittekind, C

PY - 2013

Y1 - 2013

N2 - In November 2011, the Third European Consensus Conference on Diagnosis and Treatment of Germ-Cell Cancer (GCC) was held in Berlin, Germany. This third conference followed similar meetings in 2003 (Essen, Germany) and 2006 (Amsterdam, The Netherlands) [Schmoll H-J, Souchon R, Krege S et al. European consensus on diagnosis and treatment of germ-cell cancer: a report of the European Germ-Cell Cancer Consensus Group (EGCCCG). Ann Oncol 2004; 15: 1377-1399; Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ-cell cancer: a report of the second meeting of the European Germ-Cell Cancer Consensus group (EGCCCG): part I. Eur Urol 2008; 53: 478-496; Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ-cell cancer: a report of the second meeting of the European Germ-Cell Cancer Consensus group (EGCCCG): part II. Eur Urol 2008; 53: 497-513]. A panel of 56 of 60 invited GCC experts from all across Europe discussed all aspects on diagnosis and treatment of GCC, with a particular focus on acute and late toxic effects as well as on survivorship issues. The panel consisted of oncologists, urologic surgeons, radiooncologists, pathologists and basic scientists, who are all actively involved in care of GCC patients. Panelists were chosen based on the publication activity in recent years. Before the meeting, panelists were asked to review the literature published since 2006 in 20 major areas concerning all aspects of diagnosis, treatment and follow-up of GCC patients, and to prepare an updated version of the previous recommendations to be discussed at the conference. In addition, ∼50 E-vote questions were drafted and presented at the conference to address the most controversial areas for a poll of expert opinions. Here, we present the main recommendations and controversies of this meeting. The votes of the panelists are added as online supplements.

AB - In November 2011, the Third European Consensus Conference on Diagnosis and Treatment of Germ-Cell Cancer (GCC) was held in Berlin, Germany. This third conference followed similar meetings in 2003 (Essen, Germany) and 2006 (Amsterdam, The Netherlands) [Schmoll H-J, Souchon R, Krege S et al. European consensus on diagnosis and treatment of germ-cell cancer: a report of the European Germ-Cell Cancer Consensus Group (EGCCCG). Ann Oncol 2004; 15: 1377-1399; Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ-cell cancer: a report of the second meeting of the European Germ-Cell Cancer Consensus group (EGCCCG): part I. Eur Urol 2008; 53: 478-496; Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ-cell cancer: a report of the second meeting of the European Germ-Cell Cancer Consensus group (EGCCCG): part II. Eur Urol 2008; 53: 497-513]. A panel of 56 of 60 invited GCC experts from all across Europe discussed all aspects on diagnosis and treatment of GCC, with a particular focus on acute and late toxic effects as well as on survivorship issues. The panel consisted of oncologists, urologic surgeons, radiooncologists, pathologists and basic scientists, who are all actively involved in care of GCC patients. Panelists were chosen based on the publication activity in recent years. Before the meeting, panelists were asked to review the literature published since 2006 in 20 major areas concerning all aspects of diagnosis, treatment and follow-up of GCC patients, and to prepare an updated version of the previous recommendations to be discussed at the conference. In addition, ∼50 E-vote questions were drafted and presented at the conference to address the most controversial areas for a poll of expert opinions. Here, we present the main recommendations and controversies of this meeting. The votes of the panelists are added as online supplements.

KW - Europe

KW - Follow-Up Studies

KW - Humans

KW - Neoplasm Metastasis

KW - Neoplasm Staging

KW - Neoplasms, Germ Cell and Embryonal

KW - Survival Rate

U2 - 10.1093/annonc/mds579

DO - 10.1093/annonc/mds579

M3 - SCORING: Journal article

C2 - 23152360

VL - 24

SP - 878

EP - 888

JO - ANN ONCOL

JF - ANN ONCOL

SN - 0923-7534

IS - 4

M1 - 4

ER -