Magnetic particle imaging: from proof of principle to preclinical applications
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Magnetic particle imaging: from proof of principle to preclinical applications. / Knopp, Tobias; Gdaniec, Nadine; Möddel, Martin.
in: PHYS MED BIOL, Jahrgang 62, Nr. 14, 06.2017, S. R124-R178.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Magnetic particle imaging: from proof of principle to preclinical applications
AU - Knopp, Tobias
AU - Gdaniec, Nadine
AU - Möddel, Martin
N1 - © 2017 Institute of Physics and Engineering in Medicine.
PY - 2017/6
Y1 - 2017/6
N2 - Tomographic imaging has become a mandatory tool for the diagnosis of a majority of diseases in clinical routine. Since each method has its pros and cons, a variety of methods is regularly used in the clinics to satisfy all application needs. Magnetic particle imaging (MPI) is a relatively new tomographic imaging technique that images magnetic nanoparticles with high spatio-temporal resolution in a quantitative way and in turn is highly suited for vascular and targeted imaging. MPI has been introduced in 2005 and now enters the preclinical research phase, where medical researcher get access to this new technology and exploit the potential under physiological conditions. Within this paper we review the development of MPI since its introduction in 2005. Beside an in depth description of the basic principle, we provide detailed discussions on imaging sequences, reconstruction algorithms, scanner instrumentation, and potential medical applications.
AB - Tomographic imaging has become a mandatory tool for the diagnosis of a majority of diseases in clinical routine. Since each method has its pros and cons, a variety of methods is regularly used in the clinics to satisfy all application needs. Magnetic particle imaging (MPI) is a relatively new tomographic imaging technique that images magnetic nanoparticles with high spatio-temporal resolution in a quantitative way and in turn is highly suited for vascular and targeted imaging. MPI has been introduced in 2005 and now enters the preclinical research phase, where medical researcher get access to this new technology and exploit the potential under physiological conditions. Within this paper we review the development of MPI since its introduction in 2005. Beside an in depth description of the basic principle, we provide detailed discussions on imaging sequences, reconstruction algorithms, scanner instrumentation, and potential medical applications.
KW - Journal Article
U2 - 10.1088/1361-6560/aa6c99
DO - 10.1088/1361-6560/aa6c99
M3 - SCORING: Journal article
C2 - 28398219
VL - 62
SP - R124-R178
JO - PHYS MED BIOL
JF - PHYS MED BIOL
SN - 0031-9155
IS - 14
ER -
