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Lysosome function in glomerular health and disease

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Lysosome function in glomerular health and disease. / Meyer-Schwesinger, Catherine.

in: CELL TISSUE RES, Jahrgang 385, Nr. 2, 08.2021, S. 371-392.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Meyer-Schwesinger, C 2021, 'Lysosome function in glomerular health and disease', CELL TISSUE RES, Jg. 385, Nr. 2, S. 371-392. https://doi.org/10.1007/s00441-020-03375-7

APA

Meyer-Schwesinger, C. (2021). Lysosome function in glomerular health and disease. CELL TISSUE RES, 385(2), 371-392. https://doi.org/10.1007/s00441-020-03375-7

Vancouver

Meyer-Schwesinger C. Lysosome function in glomerular health and disease. CELL TISSUE RES. 2021 Aug;385(2):371-392. https://doi.org/10.1007/s00441-020-03375-7

Bibtex

@article{265261970c22408ea28c618c480c75b9,
title = "Lysosome function in glomerular health and disease",
abstract = "The lysosome represents an important regulatory platform within numerous vesicle trafficking pathways including the endocytic, phagocytic, and autophagic pathways. Its ability to fuse with endosomes, phagosomes, and autophagosomes enables the lysosome to break down a wide range of both endogenous and exogenous cargo, including macromolecules, certain pathogens, and old or damaged organelles. Due to its center position in an intricate network of trafficking events, the lysosome has emerged as a central signaling node for sensing and orchestrating the cells metabolism and immune response, for inter-organelle and inter-cellular signaling and in membrane repair. This review highlights the current knowledge of general lysosome function and discusses these findings in their implication for renal glomerular cell types in health and disease including the involvement of glomerular cells in lysosomal storage diseases and the role of lysosomes in nongenetic glomerular injuries.",
author = "Catherine Meyer-Schwesinger",
year = "2021",
month = aug,
doi = "10.1007/s00441-020-03375-7",
language = "English",
volume = "385",
pages = "371--392",
journal = "CELL TISSUE RES",
issn = "0302-766X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Lysosome function in glomerular health and disease

AU - Meyer-Schwesinger, Catherine

PY - 2021/8

Y1 - 2021/8

N2 - The lysosome represents an important regulatory platform within numerous vesicle trafficking pathways including the endocytic, phagocytic, and autophagic pathways. Its ability to fuse with endosomes, phagosomes, and autophagosomes enables the lysosome to break down a wide range of both endogenous and exogenous cargo, including macromolecules, certain pathogens, and old or damaged organelles. Due to its center position in an intricate network of trafficking events, the lysosome has emerged as a central signaling node for sensing and orchestrating the cells metabolism and immune response, for inter-organelle and inter-cellular signaling and in membrane repair. This review highlights the current knowledge of general lysosome function and discusses these findings in their implication for renal glomerular cell types in health and disease including the involvement of glomerular cells in lysosomal storage diseases and the role of lysosomes in nongenetic glomerular injuries.

AB - The lysosome represents an important regulatory platform within numerous vesicle trafficking pathways including the endocytic, phagocytic, and autophagic pathways. Its ability to fuse with endosomes, phagosomes, and autophagosomes enables the lysosome to break down a wide range of both endogenous and exogenous cargo, including macromolecules, certain pathogens, and old or damaged organelles. Due to its center position in an intricate network of trafficking events, the lysosome has emerged as a central signaling node for sensing and orchestrating the cells metabolism and immune response, for inter-organelle and inter-cellular signaling and in membrane repair. This review highlights the current knowledge of general lysosome function and discusses these findings in their implication for renal glomerular cell types in health and disease including the involvement of glomerular cells in lysosomal storage diseases and the role of lysosomes in nongenetic glomerular injuries.

U2 - 10.1007/s00441-020-03375-7

DO - 10.1007/s00441-020-03375-7

M3 - SCORING: Review article

C2 - 33433692

VL - 385

SP - 371

EP - 392

JO - CELL TISSUE RES

JF - CELL TISSUE RES

SN - 0302-766X

IS - 2

ER -