Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.

  • Amy R Peck
  • Agnieszka K Witkiewicz
  • Chengbao Liu
  • Ginger A Stringer
  • Alexander C Klimowicz
  • Edward Pequignot
  • Boris Freydin
  • Thai H Tran
  • Ning Yang
  • Anne L Rosenberg
  • Jeffrey A Hooke
  • Albert J Kovatich
  • Marja T Nevalainen
  • Craig D Shriver
  • Terry Hyslop
  • Guido Sauter
  • David L Rimm
  • Anthony M Magliocco
  • Hallgeir Rui

Beteiligte Einrichtungen

Abstract

To investigate nuclear localized and tyrosine phosphorylated Stat5 (Nuc-pYStat5) as a marker of prognosis in node-negative breast cancer and as a predictor of response to antiestrogen therapy.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer18
ISSN0732-183X
StatusVeröffentlicht - 2011
pubmed 21576635