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Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring

Standard

Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring. / Reinshagen, K; Kabs, C; Wirth, H; Hable, N; Brade, J; Zahn, K; Hagl, C; Jester, I; Waag, K L.

in: J PEDIATR GASTR NUTR, Jahrgang 47, Nr. 5, 11.2008, S. 573-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Reinshagen, K, Kabs, C, Wirth, H, Hable, N, Brade, J, Zahn, K, Hagl, C, Jester, I & Waag, KL 2008, 'Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring', J PEDIATR GASTR NUTR, Jg. 47, Nr. 5, S. 573-8.

APA

Reinshagen, K., Kabs, C., Wirth, H., Hable, N., Brade, J., Zahn, K., Hagl, C., Jester, I., & Waag, K. L. (2008). Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring. J PEDIATR GASTR NUTR, 47(5), 573-8.

Vancouver

Reinshagen K, Kabs C, Wirth H, Hable N, Brade J, Zahn K et al. Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring. J PEDIATR GASTR NUTR. 2008 Nov;47(5):573-8.

Bibtex

@article{9188c1092e9a4d22bdded53d4ca3836d,
title = "Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring",
abstract = "OBJECTIVES: Longitudinal intestinal lengthening and tailoring (LILT) is a well-established surgical treatment for short bowel syndrome. It has been shown to enhance peristalsis, decrease bacterial overgrowth, and extend mucosal contact time for nutrients. We present the results of a long-term follow-up of patients who underwent LILT and define prognostic parameters for the survival of these patients.PATIENTS AND METHODS: Between 1987 and 2006, 53 patients underwent LILT in our institution. The main diagnoses were gastroschisis, intestinal volvulus, intestinal atresias, and necrotizing enterocolitis. LILT was performed at a mean age of 24 months (range 4144 months). The follow-up time was 79.76 months (range 6234 months).RESULTS: After LILT, 41 of 53 patients survived, and 36 of 41 surviving patients were successfully weaned from parenteral nutrition (PN). In long-term follow-up 79% stayed free of PN. The overall survival rate was 77.36%. Weight gain occurred in 58% of the patients after LILT. The quality of life after LILT is on a high level, with most patients having normal physical strength and participating in normal social life and education. Prognostic factors for survival after LILT in short bowel syndrome are length of small intestine (0.06582 + 0.0131 x bowel cm), length of large bowel (P = 0.039), preoperative liver function, and successful weaning from PN within 18 months postoperatively (P = 0.0032).CONCLUSIONS: Patients undergoing LILT in short bowel syndrome have a high survival rate, weight gain, and a high quality of life. Autologous gastrointestinal reconstruction remains therefore the first choice in the treatment of patients with short bowel syndrome.",
keywords = "Body Height, Body Weight, Child, Child, Preschool, Follow-Up Studies, Humans, Infant, Intestinal Mucosa, Intestine, Small, Intestines, Parenteral Nutrition, Retrospective Studies, Short Bowel Syndrome, Survival Rate, Survivors, Time Factors, Treatment Outcome, Journal Article",
author = "K Reinshagen and C Kabs and H Wirth and N Hable and J Brade and K Zahn and C Hagl and I Jester and Waag, {K L}",
year = "2008",
month = nov,
language = "English",
volume = "47",
pages = "573--8",
journal = "J PEDIATR GASTR NUTR",
issn = "0277-2116",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

RIS

TY - JOUR

T1 - Long-term outcome in patients with short bowel syndrome after longitudinal intestinal lengthening and tailoring

AU - Reinshagen, K

AU - Kabs, C

AU - Wirth, H

AU - Hable, N

AU - Brade, J

AU - Zahn, K

AU - Hagl, C

AU - Jester, I

AU - Waag, K L

PY - 2008/11

Y1 - 2008/11

N2 - OBJECTIVES: Longitudinal intestinal lengthening and tailoring (LILT) is a well-established surgical treatment for short bowel syndrome. It has been shown to enhance peristalsis, decrease bacterial overgrowth, and extend mucosal contact time for nutrients. We present the results of a long-term follow-up of patients who underwent LILT and define prognostic parameters for the survival of these patients.PATIENTS AND METHODS: Between 1987 and 2006, 53 patients underwent LILT in our institution. The main diagnoses were gastroschisis, intestinal volvulus, intestinal atresias, and necrotizing enterocolitis. LILT was performed at a mean age of 24 months (range 4144 months). The follow-up time was 79.76 months (range 6234 months).RESULTS: After LILT, 41 of 53 patients survived, and 36 of 41 surviving patients were successfully weaned from parenteral nutrition (PN). In long-term follow-up 79% stayed free of PN. The overall survival rate was 77.36%. Weight gain occurred in 58% of the patients after LILT. The quality of life after LILT is on a high level, with most patients having normal physical strength and participating in normal social life and education. Prognostic factors for survival after LILT in short bowel syndrome are length of small intestine (0.06582 + 0.0131 x bowel cm), length of large bowel (P = 0.039), preoperative liver function, and successful weaning from PN within 18 months postoperatively (P = 0.0032).CONCLUSIONS: Patients undergoing LILT in short bowel syndrome have a high survival rate, weight gain, and a high quality of life. Autologous gastrointestinal reconstruction remains therefore the first choice in the treatment of patients with short bowel syndrome.

AB - OBJECTIVES: Longitudinal intestinal lengthening and tailoring (LILT) is a well-established surgical treatment for short bowel syndrome. It has been shown to enhance peristalsis, decrease bacterial overgrowth, and extend mucosal contact time for nutrients. We present the results of a long-term follow-up of patients who underwent LILT and define prognostic parameters for the survival of these patients.PATIENTS AND METHODS: Between 1987 and 2006, 53 patients underwent LILT in our institution. The main diagnoses were gastroschisis, intestinal volvulus, intestinal atresias, and necrotizing enterocolitis. LILT was performed at a mean age of 24 months (range 4144 months). The follow-up time was 79.76 months (range 6234 months).RESULTS: After LILT, 41 of 53 patients survived, and 36 of 41 surviving patients were successfully weaned from parenteral nutrition (PN). In long-term follow-up 79% stayed free of PN. The overall survival rate was 77.36%. Weight gain occurred in 58% of the patients after LILT. The quality of life after LILT is on a high level, with most patients having normal physical strength and participating in normal social life and education. Prognostic factors for survival after LILT in short bowel syndrome are length of small intestine (0.06582 + 0.0131 x bowel cm), length of large bowel (P = 0.039), preoperative liver function, and successful weaning from PN within 18 months postoperatively (P = 0.0032).CONCLUSIONS: Patients undergoing LILT in short bowel syndrome have a high survival rate, weight gain, and a high quality of life. Autologous gastrointestinal reconstruction remains therefore the first choice in the treatment of patients with short bowel syndrome.

KW - Body Height

KW - Body Weight

KW - Child

KW - Child, Preschool

KW - Follow-Up Studies

KW - Humans

KW - Infant

KW - Intestinal Mucosa

KW - Intestine, Small

KW - Intestines

KW - Parenteral Nutrition

KW - Retrospective Studies

KW - Short Bowel Syndrome

KW - Survival Rate

KW - Survivors

KW - Time Factors

KW - Treatment Outcome

KW - Journal Article

M3 - SCORING: Journal article

C2 - 18979580

VL - 47

SP - 573

EP - 578

JO - J PEDIATR GASTR NUTR

JF - J PEDIATR GASTR NUTR

SN - 0277-2116

IS - 5

ER -