PortalPublikationenLong-term objective esthetic outcome after breast-conserving...

Long-term objective esthetic outcome after breast-conserving therapy

Standard

Long-term objective esthetic outcome after breast-conserving therapy. / Hennigs, André; Hartmann, Benjamin; Rauch, Geraldine; Golatta, Michael; Tabatabai, Patrik; Domschke, Christoph; Schott, Sarah; Schütz, Florian; Sohn, Christof; Heil, Joerg.

in: BREAST CANCER RES TR, Jahrgang 153, Nr. 2, 09.2015, S. 345-351.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hennigs, A, Hartmann, B, Rauch, G, Golatta, M, Tabatabai, P, Domschke, C, Schott, S, Schütz, F, Sohn, C & Heil, J 2015, 'Long-term objective esthetic outcome after breast-conserving therapy', BREAST CANCER RES TR, Jg. 153, Nr. 2, S. 345-351. https://doi.org/10.1007/s10549-015-3540-y

APA

Hennigs, A., Hartmann, B., Rauch, G., Golatta, M., Tabatabai, P., Domschke, C., Schott, S., Schütz, F., Sohn, C., & Heil, J. (2015). Long-term objective esthetic outcome after breast-conserving therapy. BREAST CANCER RES TR, 153(2), 345-351. https://doi.org/10.1007/s10549-015-3540-y

Vancouver

Hennigs A, Hartmann B, Rauch G, Golatta M, Tabatabai P, Domschke C et al. Long-term objective esthetic outcome after breast-conserving therapy. BREAST CANCER RES TR. 2015 Sep;153(2):345-351. https://doi.org/10.1007/s10549-015-3540-y

Bibtex

@article{1f4f8543ad634ee3904ad54844edcda5,
title = "Long-term objective esthetic outcome after breast-conserving therapy",
abstract = "The prediction of unfavorable long-term esthetic outcome (AO) is important for patient consultation. We aimed to analyze variables characterizing the improvement and impairment of AO over time after breast-conserving surgery. A subgroup of a prospective, monocenter cohort study was analyzed to evaluate the results of the BCCT.core software (Breast Cancer Conservative Treatment.cosmetic results) which was used to objectively assess the AO before (n = 356), shortly after (n = 294) and in median 3 years after surgery (n = 356). We analyzed potential influencing factors (such as body mass index, (y)pT-stage, weight of resected specimen, etc.) on the AO using logistic regression analyses (n = 256). Finally, we tried to characterize groups of patients with improving or impaired AO over time (n = 294). Predictors for an unfavorable AO were an axillary lymphadenectomy (OR = 4.05), a tumor in the 12 o'clock position (OR = 2.22), a tumor stage larger or equal to (y)pT2 stage (OR = 2.11), and a surgical specimen weight >75 g (OR = 2.71). Patients with lower specimen weight were more likely to improve in the long-term follow-up (p = 0.018), whereas patients with a higher (y)pT-stage tended to become impaired with time. Although overall AO decreased over time, nearly half of the patients with an unfavorable AO shortly after surgery improved in the long-term follow-up. Predictors of unfavorable AO can be used in patient consultation preoperatively to prepare them for the postsurgical period and/or to recommend surgical alternatives (e.g., more complex oncoplastic techniques). Knowledge of improvement and impairment may help patients and physicians in the postsurgical consultation setting.",
keywords = "Aged, Breast Neoplasms, Esthetics, Female, Follow-Up Studies, Humans, Mastectomy, Segmental, Middle Aged, Neoplasm Staging, Prospective Studies, Treatment Outcome, Tumor Burden, Journal Article, Research Support, Non-U.S. Gov't",
author = "Andr{\'e} Hennigs and Benjamin Hartmann and Geraldine Rauch and Michael Golatta and Patrik Tabatabai and Christoph Domschke and Sarah Schott and Florian Sch{\"u}tz and Christof Sohn and Joerg Heil",
year = "2015",
month = sep,
doi = "10.1007/s10549-015-3540-y",
language = "English",
volume = "153",
pages = "345--351",
journal = "BREAST CANCER RES TR",
issn = "0167-6806",
publisher = "Springer New York",
number = "2",

}

RIS

TY - JOUR

T1 - Long-term objective esthetic outcome after breast-conserving therapy

AU - Hennigs, André

AU - Hartmann, Benjamin

AU - Rauch, Geraldine

AU - Golatta, Michael

AU - Tabatabai, Patrik

AU - Domschke, Christoph

AU - Schott, Sarah

AU - Schütz, Florian

AU - Sohn, Christof

AU - Heil, Joerg

PY - 2015/9

Y1 - 2015/9

N2 - The prediction of unfavorable long-term esthetic outcome (AO) is important for patient consultation. We aimed to analyze variables characterizing the improvement and impairment of AO over time after breast-conserving surgery. A subgroup of a prospective, monocenter cohort study was analyzed to evaluate the results of the BCCT.core software (Breast Cancer Conservative Treatment.cosmetic results) which was used to objectively assess the AO before (n = 356), shortly after (n = 294) and in median 3 years after surgery (n = 356). We analyzed potential influencing factors (such as body mass index, (y)pT-stage, weight of resected specimen, etc.) on the AO using logistic regression analyses (n = 256). Finally, we tried to characterize groups of patients with improving or impaired AO over time (n = 294). Predictors for an unfavorable AO were an axillary lymphadenectomy (OR = 4.05), a tumor in the 12 o'clock position (OR = 2.22), a tumor stage larger or equal to (y)pT2 stage (OR = 2.11), and a surgical specimen weight >75 g (OR = 2.71). Patients with lower specimen weight were more likely to improve in the long-term follow-up (p = 0.018), whereas patients with a higher (y)pT-stage tended to become impaired with time. Although overall AO decreased over time, nearly half of the patients with an unfavorable AO shortly after surgery improved in the long-term follow-up. Predictors of unfavorable AO can be used in patient consultation preoperatively to prepare them for the postsurgical period and/or to recommend surgical alternatives (e.g., more complex oncoplastic techniques). Knowledge of improvement and impairment may help patients and physicians in the postsurgical consultation setting.

AB - The prediction of unfavorable long-term esthetic outcome (AO) is important for patient consultation. We aimed to analyze variables characterizing the improvement and impairment of AO over time after breast-conserving surgery. A subgroup of a prospective, monocenter cohort study was analyzed to evaluate the results of the BCCT.core software (Breast Cancer Conservative Treatment.cosmetic results) which was used to objectively assess the AO before (n = 356), shortly after (n = 294) and in median 3 years after surgery (n = 356). We analyzed potential influencing factors (such as body mass index, (y)pT-stage, weight of resected specimen, etc.) on the AO using logistic regression analyses (n = 256). Finally, we tried to characterize groups of patients with improving or impaired AO over time (n = 294). Predictors for an unfavorable AO were an axillary lymphadenectomy (OR = 4.05), a tumor in the 12 o'clock position (OR = 2.22), a tumor stage larger or equal to (y)pT2 stage (OR = 2.11), and a surgical specimen weight >75 g (OR = 2.71). Patients with lower specimen weight were more likely to improve in the long-term follow-up (p = 0.018), whereas patients with a higher (y)pT-stage tended to become impaired with time. Although overall AO decreased over time, nearly half of the patients with an unfavorable AO shortly after surgery improved in the long-term follow-up. Predictors of unfavorable AO can be used in patient consultation preoperatively to prepare them for the postsurgical period and/or to recommend surgical alternatives (e.g., more complex oncoplastic techniques). Knowledge of improvement and impairment may help patients and physicians in the postsurgical consultation setting.

KW - Aged

KW - Breast Neoplasms

KW - Esthetics

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Mastectomy, Segmental

KW - Middle Aged

KW - Neoplasm Staging

KW - Prospective Studies

KW - Treatment Outcome

KW - Tumor Burden

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1007/s10549-015-3540-y

DO - 10.1007/s10549-015-3540-y

M3 - SCORING: Journal article

C2 - 26267662

VL - 153

SP - 345

EP - 351

JO - BREAST CANCER RES TR

JF - BREAST CANCER RES TR

SN - 0167-6806

IS - 2

ER -