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Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial

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Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial. / Muckelbauer, Rebecca; Englert, Heike; Rieckmann, Nina; Chen, Chih-Mei; Wegscheider, Karl; Völler, Heinz; Katus, Hugo A; Willich, Stefan N; Müller-Nordhorn, Jacqueline.

in: PREV MED, Jahrgang 77, 08.2015, S. 155-61.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Muckelbauer, R, Englert, H, Rieckmann, N, Chen, C-M, Wegscheider, K, Völler, H, Katus, HA, Willich, SN & Müller-Nordhorn, J 2015, 'Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial', PREV MED, Jg. 77, S. 155-61. https://doi.org/10.1016/j.ypmed.2015.05.026

APA

Muckelbauer, R., Englert, H., Rieckmann, N., Chen, C-M., Wegscheider, K., Völler, H., Katus, H. A., Willich, S. N., & Müller-Nordhorn, J. (2015). Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial. PREV MED, 77, 155-61. https://doi.org/10.1016/j.ypmed.2015.05.026

Vancouver

Muckelbauer R, Englert H, Rieckmann N, Chen C-M, Wegscheider K, Völler H et al. Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial. PREV MED. 2015 Aug;77:155-61. https://doi.org/10.1016/j.ypmed.2015.05.026

Bibtex

@article{9b4b04f909b24aa7b74a2db03e1cfa07,
title = "Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial",
abstract = "OBJECTIVE: We evaluated the long-term effect of a smoking intervention embedded in an adherence program in patients with an increased risk for cardiovascular disease.METHOD: Secondary analysis of a randomized controlled trial: In 2002-2004, 8108 patients with hypercholesterolemia were enrolled from general practices in Germany. Patients received a 12-month adherence program and statin medication (intervention) or statin medication only (control). The program aimed to improve adherence to medication and lifestyle by educational material, mailings, and phone calls. Smoking was self-reported at baseline and every 6months during the 3-year follow-up.RESULTS: In total, 7640 patients were analyzed. At baseline, smoking prevalence was 21.7% in the intervention and 21.5% in the control group. Prevalence decreased in both groups to 16.6% vs. 19.5%, 15.3% vs. 16.8%, and 14.2% vs. 15.6% at the 12-, 24-, and 36-month follow-up. The intervention had a beneficial effect on smoking differing over time (group×time: P=0.005). The effect was largest after 6 and 12months [odds ratios (95% confidence intervals): 0.67 (0.54-0.82) and 0.63 (0.51-0.78)]. The effect decreased until the 18-month follow-up [0.72 (0.58-0.90)] and was not significant after 24months.CONCLUSION: A low-intensity smoking intervention embedded in an adherence program can contribute to smoking cessation although the intervention effect diminished over time.TRIAL REGISTRATION: ClinicalTrials.gov (www.clinicaltrials.gov): NCT00379249.",
author = "Rebecca Muckelbauer and Heike Englert and Nina Rieckmann and Chih-Mei Chen and Karl Wegscheider and Heinz V{\"o}ller and Katus, {Hugo A} and Willich, {Stefan N} and Jacqueline M{\"u}ller-Nordhorn",
note = "Copyright {\textcopyright} 2015 Elsevier Inc. All rights reserved.",
year = "2015",
month = aug,
doi = "10.1016/j.ypmed.2015.05.026",
language = "English",
volume = "77",
pages = "155--61",
journal = "PREV MED",
issn = "0091-7435",
publisher = "Academic Press Inc.",

}

RIS

TY - JOUR

T1 - Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial

AU - Muckelbauer, Rebecca

AU - Englert, Heike

AU - Rieckmann, Nina

AU - Chen, Chih-Mei

AU - Wegscheider, Karl

AU - Völler, Heinz

AU - Katus, Hugo A

AU - Willich, Stefan N

AU - Müller-Nordhorn, Jacqueline

N1 - Copyright © 2015 Elsevier Inc. All rights reserved.

PY - 2015/8

Y1 - 2015/8

N2 - OBJECTIVE: We evaluated the long-term effect of a smoking intervention embedded in an adherence program in patients with an increased risk for cardiovascular disease.METHOD: Secondary analysis of a randomized controlled trial: In 2002-2004, 8108 patients with hypercholesterolemia were enrolled from general practices in Germany. Patients received a 12-month adherence program and statin medication (intervention) or statin medication only (control). The program aimed to improve adherence to medication and lifestyle by educational material, mailings, and phone calls. Smoking was self-reported at baseline and every 6months during the 3-year follow-up.RESULTS: In total, 7640 patients were analyzed. At baseline, smoking prevalence was 21.7% in the intervention and 21.5% in the control group. Prevalence decreased in both groups to 16.6% vs. 19.5%, 15.3% vs. 16.8%, and 14.2% vs. 15.6% at the 12-, 24-, and 36-month follow-up. The intervention had a beneficial effect on smoking differing over time (group×time: P=0.005). The effect was largest after 6 and 12months [odds ratios (95% confidence intervals): 0.67 (0.54-0.82) and 0.63 (0.51-0.78)]. The effect decreased until the 18-month follow-up [0.72 (0.58-0.90)] and was not significant after 24months.CONCLUSION: A low-intensity smoking intervention embedded in an adherence program can contribute to smoking cessation although the intervention effect diminished over time.TRIAL REGISTRATION: ClinicalTrials.gov (www.clinicaltrials.gov): NCT00379249.

AB - OBJECTIVE: We evaluated the long-term effect of a smoking intervention embedded in an adherence program in patients with an increased risk for cardiovascular disease.METHOD: Secondary analysis of a randomized controlled trial: In 2002-2004, 8108 patients with hypercholesterolemia were enrolled from general practices in Germany. Patients received a 12-month adherence program and statin medication (intervention) or statin medication only (control). The program aimed to improve adherence to medication and lifestyle by educational material, mailings, and phone calls. Smoking was self-reported at baseline and every 6months during the 3-year follow-up.RESULTS: In total, 7640 patients were analyzed. At baseline, smoking prevalence was 21.7% in the intervention and 21.5% in the control group. Prevalence decreased in both groups to 16.6% vs. 19.5%, 15.3% vs. 16.8%, and 14.2% vs. 15.6% at the 12-, 24-, and 36-month follow-up. The intervention had a beneficial effect on smoking differing over time (group×time: P=0.005). The effect was largest after 6 and 12months [odds ratios (95% confidence intervals): 0.67 (0.54-0.82) and 0.63 (0.51-0.78)]. The effect decreased until the 18-month follow-up [0.72 (0.58-0.90)] and was not significant after 24months.CONCLUSION: A low-intensity smoking intervention embedded in an adherence program can contribute to smoking cessation although the intervention effect diminished over time.TRIAL REGISTRATION: ClinicalTrials.gov (www.clinicaltrials.gov): NCT00379249.

UR - http://www.ncbi.nlm.nih.gov/pubmed/26051201

UR - http://ac.els-cdn.com/S0091743515001875/1-s2.0-S0091743515001875-main.pdf?_tid=5ba40e36-d653-11e5-a045-00000aacb362&acdnat=1455809104_435b3be48f7a74eec7be2c5717ab46e3

U2 - 10.1016/j.ypmed.2015.05.026

DO - 10.1016/j.ypmed.2015.05.026

M3 - SCORING: Journal article

C2 - 26051201

VL - 77

SP - 155

EP - 161

JO - PREV MED

JF - PREV MED

SN - 0091-7435

ER -