Long-chain polyunsaturated fatty acids (LC-PUFA) during early development: contribution of milk LC-PUFA to accretion rates varies among organs.
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Long-chain polyunsaturated fatty acids (LC-PUFA) during early development: contribution of milk LC-PUFA to accretion rates varies among organs. / Hamosh, M; Henderson, T R; Kemper, Markus J.; Orr, N M; Gil, A; Hamosh, P.
in: ADV EXP MED BIOL, Jahrgang 501, 2001, S. 397-401.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Long-chain polyunsaturated fatty acids (LC-PUFA) during early development: contribution of milk LC-PUFA to accretion rates varies among organs.
AU - Hamosh, M
AU - Henderson, T R
AU - Kemper, Markus J.
AU - Orr, N M
AU - Gil, A
AU - Hamosh, P
PY - 2001
Y1 - 2001
N2 - Long-chain polyunsaturated fatty acids (LC-PUFA) accretion (essential for growth and neural development) was studied from late fetal throughout weaning age in the ferret, a species with maternal LC-PUFA sufficiency during pregnancy and lactation. The data show that a) accretion rate of LC-PUFA is rapid during early postnatal development, b) milk LC-PUFA decrease during lactation, c) adipose tissue LC-PUFA level is directly related to milk LC-PUFA level, while accretion in brain and liver exceeds dietary intake, d) accretion of arachidonic acid occurs earlier than docosahexaenoic acid, suggesting earlier development of n6-fatty acid endogenous synthesis.
AB - Long-chain polyunsaturated fatty acids (LC-PUFA) accretion (essential for growth and neural development) was studied from late fetal throughout weaning age in the ferret, a species with maternal LC-PUFA sufficiency during pregnancy and lactation. The data show that a) accretion rate of LC-PUFA is rapid during early postnatal development, b) milk LC-PUFA decrease during lactation, c) adipose tissue LC-PUFA level is directly related to milk LC-PUFA level, while accretion in brain and liver exceeds dietary intake, d) accretion of arachidonic acid occurs earlier than docosahexaenoic acid, suggesting earlier development of n6-fatty acid endogenous synthesis.
KW - Animals
KW - Humans
KW - Female
KW - Brain Chemistry
KW - Pregnancy
KW - Diet
KW - Adipose Tissue/chemistry
KW - Brain/growth & development
KW - Fatty Acids, Unsaturated/administration & dosage/analysis/physiology
KW - Ferrets/embryology/growth & development
KW - Lactation
KW - Liver/growth & development
KW - Mammary Glands, Animal/chemistry/metabolism
KW - Milk/chemistry
KW - Animals
KW - Humans
KW - Female
KW - Brain Chemistry
KW - Pregnancy
KW - Diet
KW - Adipose Tissue/chemistry
KW - Brain/growth & development
KW - Fatty Acids, Unsaturated/administration & dosage/analysis/physiology
KW - Ferrets/embryology/growth & development
KW - Lactation
KW - Liver/growth & development
KW - Mammary Glands, Animal/chemistry/metabolism
KW - Milk/chemistry
M3 - SCORING: Journal article
VL - 501
SP - 397
EP - 401
JO - ADV EXP MED BIOL
JF - ADV EXP MED BIOL
SN - 0065-2598
ER -