Long noncoding RNAs as regulators of pediatric acute myeloid leukemia

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Long noncoding RNAs as regulators of pediatric acute myeloid leukemia. / Neyazi, Sina; Ng, Michelle; Heckl, Dirk; Klusmann, Jan-Henning.

in: Molecular and cellular pediatrics, Jahrgang 9, Nr. 1, 10, 20.05.2022.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{d1340aa9fed14571a0265e0a7a817ac8,
title = "Long noncoding RNAs as regulators of pediatric acute myeloid leukemia",
abstract = "Long noncoding RNAs (lncRNAs) are increasingly emerging as regulators across human development and disease, and many have been described in the context of hematopoiesis and leukemogenesis. These studies have yielded new molecular insights into the contribution of lncRNAs to AML development and revealed connections between lncRNA expression and clinical parameters in AML patients. In this mini review, we illustrate the versatile functions of lncRNAs in AML, with a focus on pediatric AML, and present examples that may serve as future therapeutic targets or predictive factors.",
author = "Sina Neyazi and Michelle Ng and Dirk Heckl and Jan-Henning Klusmann",
note = "{\textcopyright} 2022. The Author(s).",
year = "2022",
month = may,
day = "20",
doi = "10.1186/s40348-022-00142-2",
language = "English",
volume = "9",
journal = "Molecular and cellular pediatrics",
issn = "2194-7791",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Long noncoding RNAs as regulators of pediatric acute myeloid leukemia

AU - Neyazi, Sina

AU - Ng, Michelle

AU - Heckl, Dirk

AU - Klusmann, Jan-Henning

N1 - © 2022. The Author(s).

PY - 2022/5/20

Y1 - 2022/5/20

N2 - Long noncoding RNAs (lncRNAs) are increasingly emerging as regulators across human development and disease, and many have been described in the context of hematopoiesis and leukemogenesis. These studies have yielded new molecular insights into the contribution of lncRNAs to AML development and revealed connections between lncRNA expression and clinical parameters in AML patients. In this mini review, we illustrate the versatile functions of lncRNAs in AML, with a focus on pediatric AML, and present examples that may serve as future therapeutic targets or predictive factors.

AB - Long noncoding RNAs (lncRNAs) are increasingly emerging as regulators across human development and disease, and many have been described in the context of hematopoiesis and leukemogenesis. These studies have yielded new molecular insights into the contribution of lncRNAs to AML development and revealed connections between lncRNA expression and clinical parameters in AML patients. In this mini review, we illustrate the versatile functions of lncRNAs in AML, with a focus on pediatric AML, and present examples that may serve as future therapeutic targets or predictive factors.

U2 - 10.1186/s40348-022-00142-2

DO - 10.1186/s40348-022-00142-2

M3 - SCORING: Review article

C2 - 35596093

VL - 9

JO - Molecular and cellular pediatrics

JF - Molecular and cellular pediatrics

SN - 2194-7791

IS - 1

M1 - 10

ER -