Local striatal reward signals can be predicted from corticostriatal connectivity

Peter Smittenaar; Zeb Kurth-Nelson; Siawoosh Mohammadi; Nikolaus Weiskopf; Raymond J Dolan

doi:10.1016/j.neuroimage.2017.07.042

Local striatal reward signals can be predicted from corticostriatal connectivity

Standard

Local striatal reward signals can be predicted from corticostriatal connectivity. / Smittenaar, Peter; Kurth-Nelson, Zeb; Mohammadi, Siawoosh; Weiskopf, Nikolaus; Dolan, Raymond J.

in: NEUROIMAGE, Jahrgang 159, Nr. 159, 01.10.2017, S. 9-17.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Smittenaar, P, Kurth-Nelson, Z, Mohammadi, S, Weiskopf, N & Dolan, RJ 2017, 'Local striatal reward signals can be predicted from corticostriatal connectivity', NEUROIMAGE, Jg. 159, Nr. 159, S. 9-17. https://doi.org/10.1016/j.neuroimage.2017.07.042

APA

Smittenaar, P., Kurth-Nelson, Z., Mohammadi, S., Weiskopf, N., & Dolan, R. J. (2017). Local striatal reward signals can be predicted from corticostriatal connectivity. NEUROIMAGE, 159(159), 9-17. https://doi.org/10.1016/j.neuroimage.2017.07.042

Vancouver

Smittenaar P, Kurth-Nelson Z, Mohammadi S, Weiskopf N, Dolan RJ. Local striatal reward signals can be predicted from corticostriatal connectivity. NEUROIMAGE. 2017 Okt 1;159(159):9-17. https://doi.org/10.1016/j.neuroimage.2017.07.042

Bibtex

@article{9cf981b7f71e4eabbad4f4575bdef8b9,

title = "Local striatal reward signals can be predicted from corticostriatal connectivity",

abstract = "A defining feature of the basal ganglia is their anatomical organization into multiple cortico-striatal loops. A central tenet of this architecture is the idea that local striatal function is determined by its precise connectivity with cortex, creating a functional topography that is mirrored within cortex and striatum. Here we formally test this idea using both human anatomical and functional imaging, specifically asking whether within striatal subregions one can predict between-voxel differences in functional signals based on between-voxel differences in corticostriatal connectivity. We show that corticostriatal connectivity profiles predict local variation in reward signals in bilateral caudate nucleus and putamen, expected value signals in bilateral caudate nucleus, and response effector activity in bilateral putamen. These data reveal that, even within individual striatal regions, local variability in corticostriatal anatomical connectivity predicts functional differentiation.",

keywords = "Journal Article",

author = "Peter Smittenaar and Zeb Kurth-Nelson and Siawoosh Mohammadi and Nikolaus Weiskopf and Dolan, {Raymond J}",

year = "2017",

month = oct,

day = "1",

doi = "10.1016/j.neuroimage.2017.07.042",

language = "English",

volume = "159",

pages = "9--17",

journal = "NEUROIMAGE",

issn = "1053-8119",

publisher = "Academic Press",

number = "159",

}

RIS

TY - JOUR

T1 - Local striatal reward signals can be predicted from corticostriatal connectivity

AU - Smittenaar, Peter

AU - Kurth-Nelson, Zeb

AU - Mohammadi, Siawoosh

AU - Weiskopf, Nikolaus

AU - Dolan, Raymond J

PY - 2017/10/1

Y1 - 2017/10/1

N2 - A defining feature of the basal ganglia is their anatomical organization into multiple cortico-striatal loops. A central tenet of this architecture is the idea that local striatal function is determined by its precise connectivity with cortex, creating a functional topography that is mirrored within cortex and striatum. Here we formally test this idea using both human anatomical and functional imaging, specifically asking whether within striatal subregions one can predict between-voxel differences in functional signals based on between-voxel differences in corticostriatal connectivity. We show that corticostriatal connectivity profiles predict local variation in reward signals in bilateral caudate nucleus and putamen, expected value signals in bilateral caudate nucleus, and response effector activity in bilateral putamen. These data reveal that, even within individual striatal regions, local variability in corticostriatal anatomical connectivity predicts functional differentiation.

AB - A defining feature of the basal ganglia is their anatomical organization into multiple cortico-striatal loops. A central tenet of this architecture is the idea that local striatal function is determined by its precise connectivity with cortex, creating a functional topography that is mirrored within cortex and striatum. Here we formally test this idea using both human anatomical and functional imaging, specifically asking whether within striatal subregions one can predict between-voxel differences in functional signals based on between-voxel differences in corticostriatal connectivity. We show that corticostriatal connectivity profiles predict local variation in reward signals in bilateral caudate nucleus and putamen, expected value signals in bilateral caudate nucleus, and response effector activity in bilateral putamen. These data reveal that, even within individual striatal regions, local variability in corticostriatal anatomical connectivity predicts functional differentiation.

KW - Journal Article

U2 - 10.1016/j.neuroimage.2017.07.042

DO - 10.1016/j.neuroimage.2017.07.042

M3 - SCORING: Journal article

C2 - 28736307

VL - 159

SP - 9

EP - 17

JO - NEUROIMAGE

JF - NEUROIMAGE

SN - 1053-8119

IS - 159

ER -