Liver cell transplantation in severe infantile oxalosis--a potential bridging procedure to orthotopic liver transplantation?
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Liver cell transplantation in severe infantile oxalosis--a potential bridging procedure to orthotopic liver transplantation? / Beck, Bodo B; Habbig, Sandra; Dittrich, Katalin; Stippel, Dirk; Kaul, Ingrid; Koerber, Friederike; Goebel, Heike; Salido, Eduardo C; Kemper, Markus J.; Meyburg, Jochen; Hoppe, Bernd.
in: NEPHROL DIAL TRANSPL, Jahrgang 27, Nr. 7, 7, 2012, S. 2984-2989.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Liver cell transplantation in severe infantile oxalosis--a potential bridging procedure to orthotopic liver transplantation?
AU - Beck, Bodo B
AU - Habbig, Sandra
AU - Dittrich, Katalin
AU - Stippel, Dirk
AU - Kaul, Ingrid
AU - Koerber, Friederike
AU - Goebel, Heike
AU - Salido, Eduardo C
AU - Kemper, Markus J.
AU - Meyburg, Jochen
AU - Hoppe, Bernd
PY - 2012
Y1 - 2012
N2 - The infantile form of primary hyperoxaluria type I (PHI) is the most devastating PH subtype leading to early end-stage renal failure and severe systemic oxalosis. Combined or sequential liver-kidney transplantation (LKTx) is the only curative option but it involves substantial risks, especially in critically ill infants. The procedure also requires resources that are simply not available to many children suffering from PHI worldwide. Less invasive and less complex therapeutic interventions allowing a better timing are clearly needed. Liver cell transplantation (LCT) may expand the narrow spectrum of auxiliary measures to buy time until LKTx for infants can be performed more safely.
AB - The infantile form of primary hyperoxaluria type I (PHI) is the most devastating PH subtype leading to early end-stage renal failure and severe systemic oxalosis. Combined or sequential liver-kidney transplantation (LKTx) is the only curative option but it involves substantial risks, especially in critically ill infants. The procedure also requires resources that are simply not available to many children suffering from PHI worldwide. Less invasive and less complex therapeutic interventions allowing a better timing are clearly needed. Liver cell transplantation (LCT) may expand the narrow spectrum of auxiliary measures to buy time until LKTx for infants can be performed more safely.
KW - Humans
KW - Male
KW - Female
KW - Risk Factors
KW - Prognosis
KW - Follow-Up Studies
KW - Child, Preschool
KW - Infant
KW - Cells, Cultured
KW - Pilot Projects
KW - Tissue Donors
KW - Liver Transplantation
KW - Kidney Transplantation
KW - Oxalates/metabolism
KW - Hepatocytes/cytology/transplantation
KW - Hyperoxaluria, Primary/complications/surgery
KW - Kidney Failure, Chronic/etiology
KW - Humans
KW - Male
KW - Female
KW - Risk Factors
KW - Prognosis
KW - Follow-Up Studies
KW - Child, Preschool
KW - Infant
KW - Cells, Cultured
KW - Pilot Projects
KW - Tissue Donors
KW - Liver Transplantation
KW - Kidney Transplantation
KW - Oxalates/metabolism
KW - Hepatocytes/cytology/transplantation
KW - Hyperoxaluria, Primary/complications/surgery
KW - Kidney Failure, Chronic/etiology
M3 - SCORING: Journal article
VL - 27
SP - 2984
EP - 2989
JO - NEPHROL DIAL TRANSPL
JF - NEPHROL DIAL TRANSPL
SN - 0931-0509
IS - 7
M1 - 7
ER -