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Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli

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Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli. / Hauswaldt, Susanne; Nitschke, Martin; Sayk, Friedhelm; Solbach, Werner; Knobloch, Johannes K-M.

in: CURR INFECT DIS REP, Jahrgang 15, Nr. 1, 02.2013, S. 4-9.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hauswaldt, S, Nitschke, M, Sayk, F, Solbach, W & Knobloch, JK-M 2013, 'Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli', CURR INFECT DIS REP, Jg. 15, Nr. 1, S. 4-9. https://doi.org/10.1007/s11908-012-0302-4

APA

Hauswaldt, S., Nitschke, M., Sayk, F., Solbach, W., & Knobloch, J. K-M. (2013). Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli. CURR INFECT DIS REP, 15(1), 4-9. https://doi.org/10.1007/s11908-012-0302-4

Vancouver

Hauswaldt S, Nitschke M, Sayk F, Solbach W, Knobloch JK-M. Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli. CURR INFECT DIS REP. 2013 Feb;15(1):4-9. https://doi.org/10.1007/s11908-012-0302-4

Bibtex

@article{ca74fe2f9c92446db3bb95d34c74dbb7,
title = "Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli",
abstract = "In 2011, a large outbreak caused by a Shiga toxin producing E. coli (STEC) occurred in Northern Germany, with a satellite outbreak in Western France, including the highest number of hemolytic uremic syndrome (HUS) cases ever encountered during a STEC outbreak. The outbreak strain was characterized as an enteroaggregative E. coli of serotype O104:H4 expressing a phage-encoded Shiga toxin 2. The majority of STEC infections and HUS cases were observed in adults, with a preponderance of the female gender. The outbreak imposed huge challenges on clinicians, microbiologists, and epidemiologists but also provided important new insight for the understanding of STEC infection. Thus, novel therapeutic strategies in the treatment of HUS in adults and for decolonization of long-term STEC carriers were evaluated. This review highlights the unusual features of the recent O104:H4 outbreak and focuses on emerging new strategies in diagnostics and treatment of acute STEC-related disease, as well as STEC long-term carriage.",
keywords = "Journal Article",
author = "Susanne Hauswaldt and Martin Nitschke and Friedhelm Sayk and Werner Solbach and Knobloch, {Johannes K-M}",
year = "2013",
month = feb,
doi = "10.1007/s11908-012-0302-4",
language = "English",
volume = "15",
pages = "4--9",
journal = "CURR INFECT DIS REP",
issn = "1523-3847",
publisher = "Current Science, Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli

AU - Hauswaldt, Susanne

AU - Nitschke, Martin

AU - Sayk, Friedhelm

AU - Solbach, Werner

AU - Knobloch, Johannes K-M

PY - 2013/2

Y1 - 2013/2

N2 - In 2011, a large outbreak caused by a Shiga toxin producing E. coli (STEC) occurred in Northern Germany, with a satellite outbreak in Western France, including the highest number of hemolytic uremic syndrome (HUS) cases ever encountered during a STEC outbreak. The outbreak strain was characterized as an enteroaggregative E. coli of serotype O104:H4 expressing a phage-encoded Shiga toxin 2. The majority of STEC infections and HUS cases were observed in adults, with a preponderance of the female gender. The outbreak imposed huge challenges on clinicians, microbiologists, and epidemiologists but also provided important new insight for the understanding of STEC infection. Thus, novel therapeutic strategies in the treatment of HUS in adults and for decolonization of long-term STEC carriers were evaluated. This review highlights the unusual features of the recent O104:H4 outbreak and focuses on emerging new strategies in diagnostics and treatment of acute STEC-related disease, as well as STEC long-term carriage.

AB - In 2011, a large outbreak caused by a Shiga toxin producing E. coli (STEC) occurred in Northern Germany, with a satellite outbreak in Western France, including the highest number of hemolytic uremic syndrome (HUS) cases ever encountered during a STEC outbreak. The outbreak strain was characterized as an enteroaggregative E. coli of serotype O104:H4 expressing a phage-encoded Shiga toxin 2. The majority of STEC infections and HUS cases were observed in adults, with a preponderance of the female gender. The outbreak imposed huge challenges on clinicians, microbiologists, and epidemiologists but also provided important new insight for the understanding of STEC infection. Thus, novel therapeutic strategies in the treatment of HUS in adults and for decolonization of long-term STEC carriers were evaluated. This review highlights the unusual features of the recent O104:H4 outbreak and focuses on emerging new strategies in diagnostics and treatment of acute STEC-related disease, as well as STEC long-term carriage.

KW - Journal Article

U2 - 10.1007/s11908-012-0302-4

DO - 10.1007/s11908-012-0302-4

M3 - SCORING: Journal article

C2 - 23212721

VL - 15

SP - 4

EP - 9

JO - CURR INFECT DIS REP

JF - CURR INFECT DIS REP

SN - 1523-3847

IS - 1

ER -