Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy.

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Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy. / Lewerenz, Jan; Zurowski, Bartosz; Jenicke, Lars; Bäumer, Tobias; Lees, Andrew J; Münchau, Alexander.

in: MOVEMENT DISORD, Jahrgang 20, Nr. 8, 8, 2005, S. 1071-1075.

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@article{f26612a45274468784947737d91be430,
title = "Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy.",
abstract = "We report on a patient with a residual dorsorostral midbrain lesion after resection of a pineal gland tumor. In addition to severe vertical gaze palsy, this patient exhibited other neurological features closely resembling progressive supranuclear palsy. Normal dopamine transporter single-photon emission computed tomography imaging excluded significant dopamine deficiency. We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension.",
author = "Jan Lewerenz and Bartosz Zurowski and Lars Jenicke and Tobias B{\"a}umer and Lees, {Andrew J} and Alexander M{\"u}nchau",
year = "2005",
language = "English",
volume = "20",
pages = "1071--1075",
journal = "MOVEMENT DISORD",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

RIS

TY - JOUR

T1 - Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy.

AU - Lewerenz, Jan

AU - Zurowski, Bartosz

AU - Jenicke, Lars

AU - Bäumer, Tobias

AU - Lees, Andrew J

AU - Münchau, Alexander

PY - 2005

Y1 - 2005

N2 - We report on a patient with a residual dorsorostral midbrain lesion after resection of a pineal gland tumor. In addition to severe vertical gaze palsy, this patient exhibited other neurological features closely resembling progressive supranuclear palsy. Normal dopamine transporter single-photon emission computed tomography imaging excluded significant dopamine deficiency. We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension.

AB - We report on a patient with a residual dorsorostral midbrain lesion after resection of a pineal gland tumor. In addition to severe vertical gaze palsy, this patient exhibited other neurological features closely resembling progressive supranuclear palsy. Normal dopamine transporter single-photon emission computed tomography imaging excluded significant dopamine deficiency. We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension.

M3 - SCORING: Journal article

VL - 20

SP - 1071

EP - 1075

JO - MOVEMENT DISORD

JF - MOVEMENT DISORD

SN - 0885-3185

IS - 8

M1 - 8

ER -