Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp

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Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp. / Kapustina, Irina I; Makarieva, Tatyana N; Guzii, Alla G; Kalinovsky, Anatoly I; Popov, Roman S; Dyshlovoy, Sergey A; Grebnev, Boris B; Amsberg, Gunhild von; Stonik, Valentin A.

in: MAR DRUGS, Jahrgang 18, Nr. 6, 13.06.2020.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Kapustina, II, Makarieva, TN, Guzii, AG, Kalinovsky, AI, Popov, RS, Dyshlovoy, SA, Grebnev, BB, Amsberg, GV & Stonik, VA 2020, 'Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp', MAR DRUGS, Jg. 18, Nr. 6. https://doi.org/10.3390/md18060310

APA

Kapustina, I. I., Makarieva, T. N., Guzii, A. G., Kalinovsky, A. I., Popov, R. S., Dyshlovoy, S. A., Grebnev, B. B., Amsberg, G. V., & Stonik, V. A. (2020). Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp. MAR DRUGS, 18(6). https://doi.org/10.3390/md18060310

Vancouver

Bibtex

@article{89934ab9a99f4a7a922bd8ded5a16fe5,
title = "Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp",
abstract = "Leptogorgins A-C (1-3), new humulane sesquiterpenoids, and leptogorgoid A (4), a new dihydroxyketosteroid, were isolated from the gorgonian Leptogorgia sp. collected from the South China Sea. The structures were established using MS and NMR data. The absolute configuration of 1 was confirmed by a modification of Mosher's method. Configurations of double bonds followed from NMR data, including NOE correlations. This is the first report of humulane-type sesquiterpenoids from marine invertebrates. Sesquiterpenoids leptogorgins A (1) and B (2) exhibited a moderate cytotoxicity and some selectivity against human drug-resistant prostate cancer cells 22Rv1.",
author = "Kapustina, {Irina I} and Makarieva, {Tatyana N} and Guzii, {Alla G} and Kalinovsky, {Anatoly I} and Popov, {Roman S} and Dyshlovoy, {Sergey A} and Grebnev, {Boris B} and Amsberg, {Gunhild von} and Stonik, {Valentin A}",
year = "2020",
month = jun,
day = "13",
doi = "10.3390/md18060310",
language = "English",
volume = "18",
journal = "MAR DRUGS",
issn = "1660-3397",
publisher = "MDPI AG",
number = "6",

}

RIS

TY - JOUR

T1 - Leptogorgins A-C, Humulane Sesquiterpenoids from the Vietnamese Gorgonian Leptogorgia sp

AU - Kapustina, Irina I

AU - Makarieva, Tatyana N

AU - Guzii, Alla G

AU - Kalinovsky, Anatoly I

AU - Popov, Roman S

AU - Dyshlovoy, Sergey A

AU - Grebnev, Boris B

AU - Amsberg, Gunhild von

AU - Stonik, Valentin A

PY - 2020/6/13

Y1 - 2020/6/13

N2 - Leptogorgins A-C (1-3), new humulane sesquiterpenoids, and leptogorgoid A (4), a new dihydroxyketosteroid, were isolated from the gorgonian Leptogorgia sp. collected from the South China Sea. The structures were established using MS and NMR data. The absolute configuration of 1 was confirmed by a modification of Mosher's method. Configurations of double bonds followed from NMR data, including NOE correlations. This is the first report of humulane-type sesquiterpenoids from marine invertebrates. Sesquiterpenoids leptogorgins A (1) and B (2) exhibited a moderate cytotoxicity and some selectivity against human drug-resistant prostate cancer cells 22Rv1.

AB - Leptogorgins A-C (1-3), new humulane sesquiterpenoids, and leptogorgoid A (4), a new dihydroxyketosteroid, were isolated from the gorgonian Leptogorgia sp. collected from the South China Sea. The structures were established using MS and NMR data. The absolute configuration of 1 was confirmed by a modification of Mosher's method. Configurations of double bonds followed from NMR data, including NOE correlations. This is the first report of humulane-type sesquiterpenoids from marine invertebrates. Sesquiterpenoids leptogorgins A (1) and B (2) exhibited a moderate cytotoxicity and some selectivity against human drug-resistant prostate cancer cells 22Rv1.

U2 - 10.3390/md18060310

DO - 10.3390/md18060310

M3 - SCORING: Journal article

C2 - 32545757

VL - 18

JO - MAR DRUGS

JF - MAR DRUGS

SN - 1660-3397

IS - 6

ER -