Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure

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Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure. / Jungen, Christiane; Zeus, Tobias; Balzer, Jan; Eickholt, Christian; Petersen, Margot; Kehmeier, Eva; Veulemans, Verena; Kelm, Malte; Willems, Stephan; Meyer, Christian.

in: PLOS ONE, Jahrgang 10, Nr. 10, 2015, S. e0140386.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Jungen, C, Zeus, T, Balzer, J, Eickholt, C, Petersen, M, Kehmeier, E, Veulemans, V, Kelm, M, Willems, S & Meyer, C 2015, 'Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure', PLOS ONE, Jg. 10, Nr. 10, S. e0140386. https://doi.org/10.1371/journal.pone.0140386

APA

Jungen, C., Zeus, T., Balzer, J., Eickholt, C., Petersen, M., Kehmeier, E., Veulemans, V., Kelm, M., Willems, S., & Meyer, C. (2015). Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure. PLOS ONE, 10(10), e0140386. https://doi.org/10.1371/journal.pone.0140386

Vancouver

Bibtex

@article{6ff2b7ccdc9e434d9f78cfcc5a7541b2,
title = "Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure",
abstract = "AIMS: To investigate whether percutaneous left atrial appendage (LAA) closure guided by automated real-time integration of 2D-/3D-transesophageal echocardiography (TEE) and fluoroscopy imaging results in decreased radiation exposure.METHODS AND RESULTS: In this open-label single-center study LAA closure (AmplatzerTM Cardiac Plug) was performed in 34 consecutive patients (8 women; 73.1±8.5 years) with (n = 17, EN+) or without (n = 17, EN-) integrated echocardiography/fluoroscopy imaging guidance (EchoNavigator{\textregistered} [EN]; Philips Healthcare). There were no significant differences in baseline characteristics between both groups. Successful LAA closure was documented in all patients. Radiation dose was reduced in the EN+ group about 52% (EN+: 48.5±30.7 vs. EN-: 93.9±64.4 Gy/cm2; p = 0.01). Corresponding to the radiation dose fluoroscopy time was reduced (EN+: 16.7±7 vs. EN-: 24.0±11.4 min; p = 0.035). These advantages were not at the cost of increased procedure time (89.6±28.8 vs. 90.1±30.2 min; p = 0.96) or periprocedural complications. Contrast media amount was comparable between both groups (172.3±92.7 vs. 197.5±127.8 ml; p = 0.53). During short-term follow-up of at least 3 months (mean: 8.1±5.9 months) no device-related events occurred.CONCLUSIONS: Automated real-time integration of echocardiography and fluoroscopy can be incorporated into procedural work-flow of percutaneous left atrial appendage closure without prolonging procedure time. This approach results in a relevant reduction of radiation exposure.TRIAL REGISTRATION: ClinicalTrials.gov NCT01262508.",
keywords = "Aged, Aged, 80 and over, Atrial Appendage/diagnostic imaging, Echocardiography, Endosonography, Female, Fluoroscopy, Humans, Male, Middle Aged, Multimodal Imaging, Radiation Dosage",
author = "Christiane Jungen and Tobias Zeus and Jan Balzer and Christian Eickholt and Margot Petersen and Eva Kehmeier and Verena Veulemans and Malte Kelm and Stephan Willems and Christian Meyer",
year = "2015",
doi = "10.1371/journal.pone.0140386",
language = "English",
volume = "10",
pages = "e0140386",
journal = "PLOS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "10",

}

RIS

TY - JOUR

T1 - Left Atrial Appendage Closure Guided by Integrated Echocardiography and Fluoroscopy Imaging Reduces Radiation Exposure

AU - Jungen, Christiane

AU - Zeus, Tobias

AU - Balzer, Jan

AU - Eickholt, Christian

AU - Petersen, Margot

AU - Kehmeier, Eva

AU - Veulemans, Verena

AU - Kelm, Malte

AU - Willems, Stephan

AU - Meyer, Christian

PY - 2015

Y1 - 2015

N2 - AIMS: To investigate whether percutaneous left atrial appendage (LAA) closure guided by automated real-time integration of 2D-/3D-transesophageal echocardiography (TEE) and fluoroscopy imaging results in decreased radiation exposure.METHODS AND RESULTS: In this open-label single-center study LAA closure (AmplatzerTM Cardiac Plug) was performed in 34 consecutive patients (8 women; 73.1±8.5 years) with (n = 17, EN+) or without (n = 17, EN-) integrated echocardiography/fluoroscopy imaging guidance (EchoNavigator® [EN]; Philips Healthcare). There were no significant differences in baseline characteristics between both groups. Successful LAA closure was documented in all patients. Radiation dose was reduced in the EN+ group about 52% (EN+: 48.5±30.7 vs. EN-: 93.9±64.4 Gy/cm2; p = 0.01). Corresponding to the radiation dose fluoroscopy time was reduced (EN+: 16.7±7 vs. EN-: 24.0±11.4 min; p = 0.035). These advantages were not at the cost of increased procedure time (89.6±28.8 vs. 90.1±30.2 min; p = 0.96) or periprocedural complications. Contrast media amount was comparable between both groups (172.3±92.7 vs. 197.5±127.8 ml; p = 0.53). During short-term follow-up of at least 3 months (mean: 8.1±5.9 months) no device-related events occurred.CONCLUSIONS: Automated real-time integration of echocardiography and fluoroscopy can be incorporated into procedural work-flow of percutaneous left atrial appendage closure without prolonging procedure time. This approach results in a relevant reduction of radiation exposure.TRIAL REGISTRATION: ClinicalTrials.gov NCT01262508.

AB - AIMS: To investigate whether percutaneous left atrial appendage (LAA) closure guided by automated real-time integration of 2D-/3D-transesophageal echocardiography (TEE) and fluoroscopy imaging results in decreased radiation exposure.METHODS AND RESULTS: In this open-label single-center study LAA closure (AmplatzerTM Cardiac Plug) was performed in 34 consecutive patients (8 women; 73.1±8.5 years) with (n = 17, EN+) or without (n = 17, EN-) integrated echocardiography/fluoroscopy imaging guidance (EchoNavigator® [EN]; Philips Healthcare). There were no significant differences in baseline characteristics between both groups. Successful LAA closure was documented in all patients. Radiation dose was reduced in the EN+ group about 52% (EN+: 48.5±30.7 vs. EN-: 93.9±64.4 Gy/cm2; p = 0.01). Corresponding to the radiation dose fluoroscopy time was reduced (EN+: 16.7±7 vs. EN-: 24.0±11.4 min; p = 0.035). These advantages were not at the cost of increased procedure time (89.6±28.8 vs. 90.1±30.2 min; p = 0.96) or periprocedural complications. Contrast media amount was comparable between both groups (172.3±92.7 vs. 197.5±127.8 ml; p = 0.53). During short-term follow-up of at least 3 months (mean: 8.1±5.9 months) no device-related events occurred.CONCLUSIONS: Automated real-time integration of echocardiography and fluoroscopy can be incorporated into procedural work-flow of percutaneous left atrial appendage closure without prolonging procedure time. This approach results in a relevant reduction of radiation exposure.TRIAL REGISTRATION: ClinicalTrials.gov NCT01262508.

KW - Aged

KW - Aged, 80 and over

KW - Atrial Appendage/diagnostic imaging

KW - Echocardiography

KW - Endosonography

KW - Female

KW - Fluoroscopy

KW - Humans

KW - Male

KW - Middle Aged

KW - Multimodal Imaging

KW - Radiation Dosage

U2 - 10.1371/journal.pone.0140386

DO - 10.1371/journal.pone.0140386

M3 - SCORING: Journal article

C2 - 26465747

VL - 10

SP - e0140386

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 10

ER -