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Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.

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Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery. / Fuerst, Martin; Möhl, Henrike; Baumgärtel, Kerstin; Rüther, Wolfgang.

in: RHEUMATOL INT, Jahrgang 26, Nr. 12, 12, 2006, S. 1138-1142.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Fuerst, M, Möhl, H, Baumgärtel, K & Rüther, W 2006, 'Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.', RHEUMATOL INT, Jg. 26, Nr. 12, 12, S. 1138-1142. <http://www.ncbi.nlm.nih.gov/pubmed/16736164?dopt=Citation>

APA

Fuerst, M., Möhl, H., Baumgärtel, K., & Rüther, W. (2006). Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery. RHEUMATOL INT, 26(12), 1138-1142. [12]. http://www.ncbi.nlm.nih.gov/pubmed/16736164?dopt=Citation

Vancouver

Fuerst M, Möhl H, Baumgärtel K, Rüther W. Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery. RHEUMATOL INT. 2006;26(12):1138-1142. 12.

Bibtex

@article{b0977b4e22fb4a2eae318557e8f62da7,
title = "Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.",
abstract = "The aim of this object is to study whether treatment with biological or leflunomide increases the risk of wound-healing complications after elective orthopedic surgery. Between March 2002 and September 2003, 201 patients participated in this study with the following inclusion criteria: (a) Rheumatoid arthritis (RA) or psoriatic arthritis (psA), (b) therapy with: MTX, leflunomide, etanercept, infliximab, adalimumab, anakinra, (c) undergoing elective orthopedic surgery. The incidence of early postoperative wound-healing complications was compared among the different groups. In comparison with patients who received MTX therapy (n = 59), the risk of postoperative wound-healing complications in patients undergoing leflunomide therapy (n = 32) was significantly higher: 13.6% in the MTX group, 40.6% in the leflunomide group (P = 0.01). It is recommended that leflunomide medication for patients with RA undergoing elective orthopedic surgical procedure is interrupted preoperatively to reduce the risk of early wound-healing complications or infections.",
author = "Martin Fuerst and Henrike M{\"o}hl and Kerstin Baumg{\"a}rtel and Wolfgang R{\"u}ther",
year = "2006",
language = "Deutsch",
volume = "26",
pages = "1138--1142",
journal = "RHEUMATOL INT",
issn = "0172-8172",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.

AU - Fuerst, Martin

AU - Möhl, Henrike

AU - Baumgärtel, Kerstin

AU - Rüther, Wolfgang

PY - 2006

Y1 - 2006

N2 - The aim of this object is to study whether treatment with biological or leflunomide increases the risk of wound-healing complications after elective orthopedic surgery. Between March 2002 and September 2003, 201 patients participated in this study with the following inclusion criteria: (a) Rheumatoid arthritis (RA) or psoriatic arthritis (psA), (b) therapy with: MTX, leflunomide, etanercept, infliximab, adalimumab, anakinra, (c) undergoing elective orthopedic surgery. The incidence of early postoperative wound-healing complications was compared among the different groups. In comparison with patients who received MTX therapy (n = 59), the risk of postoperative wound-healing complications in patients undergoing leflunomide therapy (n = 32) was significantly higher: 13.6% in the MTX group, 40.6% in the leflunomide group (P = 0.01). It is recommended that leflunomide medication for patients with RA undergoing elective orthopedic surgical procedure is interrupted preoperatively to reduce the risk of early wound-healing complications or infections.

AB - The aim of this object is to study whether treatment with biological or leflunomide increases the risk of wound-healing complications after elective orthopedic surgery. Between March 2002 and September 2003, 201 patients participated in this study with the following inclusion criteria: (a) Rheumatoid arthritis (RA) or psoriatic arthritis (psA), (b) therapy with: MTX, leflunomide, etanercept, infliximab, adalimumab, anakinra, (c) undergoing elective orthopedic surgery. The incidence of early postoperative wound-healing complications was compared among the different groups. In comparison with patients who received MTX therapy (n = 59), the risk of postoperative wound-healing complications in patients undergoing leflunomide therapy (n = 32) was significantly higher: 13.6% in the MTX group, 40.6% in the leflunomide group (P = 0.01). It is recommended that leflunomide medication for patients with RA undergoing elective orthopedic surgical procedure is interrupted preoperatively to reduce the risk of early wound-healing complications or infections.

M3 - SCORING: Zeitschriftenaufsatz

VL - 26

SP - 1138

EP - 1142

JO - RHEUMATOL INT

JF - RHEUMATOL INT

SN - 0172-8172

IS - 12

M1 - 12

ER -