Late-onset depression with mild cognitive deficits: electrophysiological evidences for a preclinical dementia syndrome.

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Late-onset depression with mild cognitive deficits: electrophysiological evidences for a preclinical dementia syndrome. / Brassen, Stefanie; Braus, Dieter F; Weber-Fahr, Wolfgang; Tost, Heike; Moritz, Steffen; Adler, Georg.

in: DEMENT GERIATR COGN, Jahrgang 18, Nr. 3-4, 3-4, 2004, S. 271-277.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{8a174cce8d9b459d886a51ba81ce2ad8,
title = "Late-onset depression with mild cognitive deficits: electrophysiological evidences for a preclinical dementia syndrome.",
abstract = "Mild cognitive impairment (MCI) is present in up to 60% of patients with late-onset depression and constitutes a major diagnostic problem in geriatric psychiatry. Searching for sensitive markers for the detection of early brain changes suggestive of dementia, we compared this depressive risk population with mildly to moderately demented patients and cognitively unimpaired depressed patients using EEG power and coherence. We found a considerable similarity between Alzheimer's disease patients and cognitively impaired depressed patients regarding the cognitive profile and EEG pattern. Changes in EEG power and coherence at frontotemporal leads in depressive patients with MCI thereby allowed discrimination from cognitively unimpaired patients with a sensitivity of 88% and a specifity of 81%.",
author = "Stefanie Brassen and Braus, {Dieter F} and Wolfgang Weber-Fahr and Heike Tost and Steffen Moritz and Georg Adler",
year = "2004",
language = "Deutsch",
volume = "18",
pages = "271--277",
journal = "DEMENT GERIATR COGN",
issn = "1420-8008",
publisher = "S. Karger AG",
number = "3-4",

}

RIS

TY - JOUR

T1 - Late-onset depression with mild cognitive deficits: electrophysiological evidences for a preclinical dementia syndrome.

AU - Brassen, Stefanie

AU - Braus, Dieter F

AU - Weber-Fahr, Wolfgang

AU - Tost, Heike

AU - Moritz, Steffen

AU - Adler, Georg

PY - 2004

Y1 - 2004

N2 - Mild cognitive impairment (MCI) is present in up to 60% of patients with late-onset depression and constitutes a major diagnostic problem in geriatric psychiatry. Searching for sensitive markers for the detection of early brain changes suggestive of dementia, we compared this depressive risk population with mildly to moderately demented patients and cognitively unimpaired depressed patients using EEG power and coherence. We found a considerable similarity between Alzheimer's disease patients and cognitively impaired depressed patients regarding the cognitive profile and EEG pattern. Changes in EEG power and coherence at frontotemporal leads in depressive patients with MCI thereby allowed discrimination from cognitively unimpaired patients with a sensitivity of 88% and a specifity of 81%.

AB - Mild cognitive impairment (MCI) is present in up to 60% of patients with late-onset depression and constitutes a major diagnostic problem in geriatric psychiatry. Searching for sensitive markers for the detection of early brain changes suggestive of dementia, we compared this depressive risk population with mildly to moderately demented patients and cognitively unimpaired depressed patients using EEG power and coherence. We found a considerable similarity between Alzheimer's disease patients and cognitively impaired depressed patients regarding the cognitive profile and EEG pattern. Changes in EEG power and coherence at frontotemporal leads in depressive patients with MCI thereby allowed discrimination from cognitively unimpaired patients with a sensitivity of 88% and a specifity of 81%.

M3 - SCORING: Zeitschriftenaufsatz

VL - 18

SP - 271

EP - 277

JO - DEMENT GERIATR COGN

JF - DEMENT GERIATR COGN

SN - 1420-8008

IS - 3-4

M1 - 3-4

ER -