Knochen- und Fettgewebebildung
Standard
Knochen- und Fettgewebebildung. / Luther, J; David, J-P.
in: Z RHEUMATOL, Jahrgang 75, Nr. 7, 09.2016, S. 701-6.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Knochen- und Fettgewebebildung
AU - Luther, J
AU - David, J-P
PY - 2016/9
Y1 - 2016/9
N2 - Leptin has been described to have a crucial role in bone homeostasis by systemic as well as local action. Systemically, leptin seems to inhibit bone formation controlled by a feedback loop including osteocalcin and insulin. Even though the action seems to be bone site specific, as well as gender- and time-dependent, the results showing the interaction of these three factors are in part still inconsistent. In this article the complex effects of leptin, insulin, and osteocalcin on bone and fat metabolism are summarized.
AB - Leptin has been described to have a crucial role in bone homeostasis by systemic as well as local action. Systemically, leptin seems to inhibit bone formation controlled by a feedback loop including osteocalcin and insulin. Even though the action seems to be bone site specific, as well as gender- and time-dependent, the results showing the interaction of these three factors are in part still inconsistent. In this article the complex effects of leptin, insulin, and osteocalcin on bone and fat metabolism are summarized.
KW - English Abstract
KW - Journal Article
U2 - 10.1007/s00393-016-0166-3
DO - 10.1007/s00393-016-0166-3
M3 - SCORING: Zeitschriftenaufsatz
C2 - 27535274
VL - 75
SP - 701
EP - 706
JO - Z RHEUMATOL
JF - Z RHEUMATOL
SN - 0340-1855
IS - 7
ER -