Kieferhöhlenbeteiligungen im Rahmen der Langers-Zell-Histiozytose

TY - JOUR

T1 - Kieferhöhlenbeteiligungen im Rahmen der Langers-Zell-Histiozytose

AU - Bartnick, A

AU - Friedrich, R E

AU - Röser, K

AU - Schmelzle, R

PY - 2003/1/1

Y1 - 2003/1/1

N2 - AIM: A clinical presentation of Langerhans cell histiocytosis (LCH) in the maxillary sinus of two patients is given. LCH in the maxillary sinus is a rare occurrence. Our aim was to compare the different treatment alternatives available and to suggest a classification as well as a therapeutic regime.PATIENTS AND METHOD: Records and clinical data of two patients treated between 1994 and 2001 were retrospectively evaluated. Both patients suffered from LCH in the maxillary sinus and the maxilla regions. Only surgical treatment was used. After resection, a large defect of the maxillary sinus, which did not allowing coverage, was seen in both cases. After reconstructive operations, closure was finally achieved. Both patients underwent follow-ups, whereby one suffered from a relapse after 15 months.RESULTS: Although one of the patients under investigation showed a recurrence of LCH, we are of the opinion that surgical treatment is very effective in the elimination of this condition. A proposal for a classification of LCH in the oral-maxillo-facial-region is made.CONCLUSIONS: The evaluation of our clinical study suggests that LCH is a disease that should be treated surgically. Only in very severe cases should the surgical treatment be complimented by either radiotherapy or chemotherapy. In disseminated cases, especially chemotherapy seems to improve the outcome. Surgery offers the possibility of eliminating systemic side effects.

AB - AIM: A clinical presentation of Langerhans cell histiocytosis (LCH) in the maxillary sinus of two patients is given. LCH in the maxillary sinus is a rare occurrence. Our aim was to compare the different treatment alternatives available and to suggest a classification as well as a therapeutic regime.PATIENTS AND METHOD: Records and clinical data of two patients treated between 1994 and 2001 were retrospectively evaluated. Both patients suffered from LCH in the maxillary sinus and the maxilla regions. Only surgical treatment was used. After resection, a large defect of the maxillary sinus, which did not allowing coverage, was seen in both cases. After reconstructive operations, closure was finally achieved. Both patients underwent follow-ups, whereby one suffered from a relapse after 15 months.RESULTS: Although one of the patients under investigation showed a recurrence of LCH, we are of the opinion that surgical treatment is very effective in the elimination of this condition. A proposal for a classification of LCH in the oral-maxillo-facial-region is made.CONCLUSIONS: The evaluation of our clinical study suggests that LCH is a disease that should be treated surgically. Only in very severe cases should the surgical treatment be complimented by either radiotherapy or chemotherapy. In disseminated cases, especially chemotherapy seems to improve the outcome. Surgery offers the possibility of eliminating systemic side effects.

KW - Dental Implantation, Endosseous

KW - Follow-Up Studies

KW - Histiocytosis, Langerhans-Cell

KW - Humans

KW - Male

KW - Maxillary Sinus

KW - Paranasal Sinus Diseases

KW - Postoperative Complications

KW - Reoperation

KW - Retrospective Studies

KW - Surgical Flaps

KW - Tooth Extraction

U2 - 10.1007/s10006-002-0433-0

DO - 10.1007/s10006-002-0433-0

M3 - SCORING: Zeitschriftenaufsatz

C2 - 12556984

VL - 7

SP - 36

EP - 41

IS - 1

ER -