Investigation of the differentiation of ex vivo nerve and fat tissues using laser-induced breakdown spectroscopy (LIBS): Prospects for tissue-specific laser surgery

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Investigation of the differentiation of ex vivo nerve and fat tissues using laser-induced breakdown spectroscopy (LIBS): Prospects for tissue-specific laser surgery. / Mehari, Fanuel; Kanawade, Rajesh; Knipfer, Christian; Adler, Werner; Klämpfl, Florian; Stelzle, Florian; Schmidt, Michael; Rohde, Maximilian.

in: J BIOPHOTONICS, Jahrgang 9, Nr. 10, 10.2016, S. 1021-1032.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{c4f34ba5e9874e9db43de4837479ac03,
title = "Investigation of the differentiation of ex vivo nerve and fat tissues using laser-induced breakdown spectroscopy (LIBS): Prospects for tissue-specific laser surgery",
abstract = "In the present study, the elemental compositions of fat and nerve tissue during their plasma mediated laser ablation are studied in the context of tissue differentiation for laser surgery applications by using Laser-Induced Breakdown Spectroscopy (LIBS). Tissue samples of porcine fat and nerve were prepared as ex vivo experimental objects. Plasma mediated laser ablation is performed using an Nd : YAG laser in open air and under normal stray light conditions. The performed measurements suggest that the two tissue types show a high similarity in terms of qualitative elemental composition while at the same time revealing a distinct difference in the concentration of the constituent elements. Different analysis approaches are evaluated and discussed to optimize the tissue-differentiation performance of the LIBS approach. Plasma mediated laser tissue ablation.",
keywords = "Journal Article",
author = "Fanuel Mehari and Rajesh Kanawade and Christian Knipfer and Werner Adler and Florian Kl{\"a}mpfl and Florian Stelzle and Michael Schmidt and Maximilian Rohde",
note = "{\textcopyright} 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2016",
month = oct,
doi = "10.1002/jbio.201500256",
language = "English",
volume = "9",
pages = "1021--1032",
journal = "J BIOPHOTONICS",
issn = "1864-063X",
publisher = "Wiley-VCH Verlag GmbH",
number = "10",

}

RIS

TY - JOUR

T1 - Investigation of the differentiation of ex vivo nerve and fat tissues using laser-induced breakdown spectroscopy (LIBS): Prospects for tissue-specific laser surgery

AU - Mehari, Fanuel

AU - Kanawade, Rajesh

AU - Knipfer, Christian

AU - Adler, Werner

AU - Klämpfl, Florian

AU - Stelzle, Florian

AU - Schmidt, Michael

AU - Rohde, Maximilian

N1 - © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2016/10

Y1 - 2016/10

N2 - In the present study, the elemental compositions of fat and nerve tissue during their plasma mediated laser ablation are studied in the context of tissue differentiation for laser surgery applications by using Laser-Induced Breakdown Spectroscopy (LIBS). Tissue samples of porcine fat and nerve were prepared as ex vivo experimental objects. Plasma mediated laser ablation is performed using an Nd : YAG laser in open air and under normal stray light conditions. The performed measurements suggest that the two tissue types show a high similarity in terms of qualitative elemental composition while at the same time revealing a distinct difference in the concentration of the constituent elements. Different analysis approaches are evaluated and discussed to optimize the tissue-differentiation performance of the LIBS approach. Plasma mediated laser tissue ablation.

AB - In the present study, the elemental compositions of fat and nerve tissue during their plasma mediated laser ablation are studied in the context of tissue differentiation for laser surgery applications by using Laser-Induced Breakdown Spectroscopy (LIBS). Tissue samples of porcine fat and nerve were prepared as ex vivo experimental objects. Plasma mediated laser ablation is performed using an Nd : YAG laser in open air and under normal stray light conditions. The performed measurements suggest that the two tissue types show a high similarity in terms of qualitative elemental composition while at the same time revealing a distinct difference in the concentration of the constituent elements. Different analysis approaches are evaluated and discussed to optimize the tissue-differentiation performance of the LIBS approach. Plasma mediated laser tissue ablation.

KW - Journal Article

U2 - 10.1002/jbio.201500256

DO - 10.1002/jbio.201500256

M3 - SCORING: Journal article

C2 - 26790774

VL - 9

SP - 1021

EP - 1032

JO - J BIOPHOTONICS

JF - J BIOPHOTONICS

SN - 1864-063X

IS - 10

ER -