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Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation

Standard

Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation. / Sultan, Arian; Steven, Daniel; Rostock, Thomas; Hoffmann, Boris; Müllerleile, Kai; Servatius, Helge; Drewitz, Imke; Lüker, Jakob; Meyer, Philip; Salukhe, Tushar; Willems, Stephan.

in: J CARDIOVASC ELECTR, Jahrgang 23, Nr. 1, 01.2012, S. 54-59.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Sultan, A, Steven, D, Rostock, T, Hoffmann, B, Müllerleile, K, Servatius, H, Drewitz, I, Lüker, J, Meyer, P, Salukhe, T & Willems, S 2012, 'Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation', J CARDIOVASC ELECTR, Jg. 23, Nr. 1, S. 54-59. https://doi.org/10.1111/j.1540-8167.2011.02146.x

APA

Sultan, A., Steven, D., Rostock, T., Hoffmann, B., Müllerleile, K., Servatius, H., Drewitz, I., Lüker, J., Meyer, P., Salukhe, T., & Willems, S. (2012). Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation. J CARDIOVASC ELECTR, 23(1), 54-59. https://doi.org/10.1111/j.1540-8167.2011.02146.x

Vancouver

Sultan A, Steven D, Rostock T, Hoffmann B, Müllerleile K, Servatius H et al. Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation. J CARDIOVASC ELECTR. 2012 Jan;23(1):54-59. https://doi.org/10.1111/j.1540-8167.2011.02146.x

Bibtex

@article{896819a57387429e9d0c930cf8dd1a7b,
title = "Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation",
abstract = "BACKGROUND: External biphasic electrical cardioversion (CV) is a standard treatment option for patients suffering from acute symptoms of atrial fibrillation (AF). Nevertheless, CV is not always successful, and thus strategies to increase the success rate are desirable.OBJECTIVE: The purpose of this study was to evaluate the effect of intravenously administered K/Mg solution on the biphasic CV energy threshold and success rate to restore sinus rhythm (SR) in patients with AF.METHODS: The study consisted of 170 patients with persistent AF. The patients were randomly assigned to undergo biphasic CV either with (n = 84) or without (n = 86) pretreatment with K/Mg solution. An energy step-up protocol of 75, 100, and 150 W (J) was used.RESULTS: Biphasic CV of AF was effective in 81 (96.4%) patients in the pretreatment and 74 (86.0%) patients in the control group (P = 0.005). The effective energy level required to achieve SR was significantly lower in the pretreated group (140.8 ± 26.9 J vs 182.5 ± 52.2 J, P = 0.02). No K/Mg-solution-associated side effects such as hypotension or bradycardia were observed.CONCLUSION: Administration of K/Mg solution positively influences the success rate of CV in patients with persistent AF. Furthermore, significantly less energy is required to successfully restore SR and therefore K/Mg pretreatment may facilitate SR restoration in patients undergoing CV for AF.",
keywords = "Aged, Atrial Fibrillation/diagnosis, Combined Modality Therapy, Defibrillators, Electric Countershock/adverse effects, Female, Germany, Humans, Infusions, Intravenous, Magnesium/administration & dosage, Male, Middle Aged, Potassium/administration & dosage, Treatment Outcome",
author = "Arian Sultan and Daniel Steven and Thomas Rostock and Boris Hoffmann and Kai M{\"u}llerleile and Helge Servatius and Imke Drewitz and Jakob L{\"u}ker and Philip Meyer and Tushar Salukhe and Stephan Willems",
note = "{\textcopyright} 2011 Wiley Periodicals, Inc.",
year = "2012",
month = jan,
doi = "10.1111/j.1540-8167.2011.02146.x",
language = "English",
volume = "23",
pages = "54--59",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation

AU - Sultan, Arian

AU - Steven, Daniel

AU - Rostock, Thomas

AU - Hoffmann, Boris

AU - Müllerleile, Kai

AU - Servatius, Helge

AU - Drewitz, Imke

AU - Lüker, Jakob

AU - Meyer, Philip

AU - Salukhe, Tushar

AU - Willems, Stephan

N1 - © 2011 Wiley Periodicals, Inc.

PY - 2012/1

Y1 - 2012/1

N2 - BACKGROUND: External biphasic electrical cardioversion (CV) is a standard treatment option for patients suffering from acute symptoms of atrial fibrillation (AF). Nevertheless, CV is not always successful, and thus strategies to increase the success rate are desirable.OBJECTIVE: The purpose of this study was to evaluate the effect of intravenously administered K/Mg solution on the biphasic CV energy threshold and success rate to restore sinus rhythm (SR) in patients with AF.METHODS: The study consisted of 170 patients with persistent AF. The patients were randomly assigned to undergo biphasic CV either with (n = 84) or without (n = 86) pretreatment with K/Mg solution. An energy step-up protocol of 75, 100, and 150 W (J) was used.RESULTS: Biphasic CV of AF was effective in 81 (96.4%) patients in the pretreatment and 74 (86.0%) patients in the control group (P = 0.005). The effective energy level required to achieve SR was significantly lower in the pretreated group (140.8 ± 26.9 J vs 182.5 ± 52.2 J, P = 0.02). No K/Mg-solution-associated side effects such as hypotension or bradycardia were observed.CONCLUSION: Administration of K/Mg solution positively influences the success rate of CV in patients with persistent AF. Furthermore, significantly less energy is required to successfully restore SR and therefore K/Mg pretreatment may facilitate SR restoration in patients undergoing CV for AF.

AB - BACKGROUND: External biphasic electrical cardioversion (CV) is a standard treatment option for patients suffering from acute symptoms of atrial fibrillation (AF). Nevertheless, CV is not always successful, and thus strategies to increase the success rate are desirable.OBJECTIVE: The purpose of this study was to evaluate the effect of intravenously administered K/Mg solution on the biphasic CV energy threshold and success rate to restore sinus rhythm (SR) in patients with AF.METHODS: The study consisted of 170 patients with persistent AF. The patients were randomly assigned to undergo biphasic CV either with (n = 84) or without (n = 86) pretreatment with K/Mg solution. An energy step-up protocol of 75, 100, and 150 W (J) was used.RESULTS: Biphasic CV of AF was effective in 81 (96.4%) patients in the pretreatment and 74 (86.0%) patients in the control group (P = 0.005). The effective energy level required to achieve SR was significantly lower in the pretreated group (140.8 ± 26.9 J vs 182.5 ± 52.2 J, P = 0.02). No K/Mg-solution-associated side effects such as hypotension or bradycardia were observed.CONCLUSION: Administration of K/Mg solution positively influences the success rate of CV in patients with persistent AF. Furthermore, significantly less energy is required to successfully restore SR and therefore K/Mg pretreatment may facilitate SR restoration in patients undergoing CV for AF.

KW - Aged

KW - Atrial Fibrillation/diagnosis

KW - Combined Modality Therapy

KW - Defibrillators

KW - Electric Countershock/adverse effects

KW - Female

KW - Germany

KW - Humans

KW - Infusions, Intravenous

KW - Magnesium/administration & dosage

KW - Male

KW - Middle Aged

KW - Potassium/administration & dosage

KW - Treatment Outcome

U2 - 10.1111/j.1540-8167.2011.02146.x

DO - 10.1111/j.1540-8167.2011.02146.x

M3 - SCORING: Journal article

C2 - 21815963

VL - 23

SP - 54

EP - 59

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 1

ER -