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Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT)

Standard

Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT). / Kouz, Karim; Monge García, Manuel Ignacio; Cerutti, Elisabetta; Lisanti, Ivana; Draisci, Gaetano; Frassanito, Luciano; Sander, Michael; Ali Akbari, Amir; Frey, Ulrich H; Grundmann, Carla Davina; Davies, Simon James; Donati, Abele; Ripolles-Melchor, Javier; García-López, Daniel; Vojnar, Benjamin; Gayat, Étienne; Noll, Eric; Bramlage, Peter; Saugel, Bernd.

in: BJA Open, Jahrgang 6, 06.2023, S. 100140.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kouz, K, Monge García, MI, Cerutti, E, Lisanti, I, Draisci, G, Frassanito, L, Sander, M, Ali Akbari, A, Frey, UH, Grundmann, CD, Davies, SJ, Donati, A, Ripolles-Melchor, J, García-López, D, Vojnar, B, Gayat, É, Noll, E, Bramlage, P & Saugel, B 2023, 'Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT)', BJA Open, Jg. 6, S. 100140. https://doi.org/10.1016/j.bjao.2023.100140

APA

Kouz, K., Monge García, M. I., Cerutti, E., Lisanti, I., Draisci, G., Frassanito, L., Sander, M., Ali Akbari, A., Frey, U. H., Grundmann, C. D., Davies, S. J., Donati, A., Ripolles-Melchor, J., García-López, D., Vojnar, B., Gayat, É., Noll, E., Bramlage, P., & Saugel, B. (2023). Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT). BJA Open, 6, 100140. https://doi.org/10.1016/j.bjao.2023.100140

Vancouver

Kouz K, Monge García MI, Cerutti E, Lisanti I, Draisci G, Frassanito L et al. Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT). BJA Open. 2023 Jun;6:100140. https://doi.org/10.1016/j.bjao.2023.100140

Bibtex

@article{462edb654a904ced850681ce7659d3c8,
title = "Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT)",
abstract = "BACKGROUND: Intraoperative hypotension is associated with organ injury. Current intraoperative arterial pressure management is mainly reactive. Predictive haemodynamic monitoring may help clinicians reduce intraoperative hypotension. The Acumen{\texttrademark} Hypotension Prediction Index software (HPI-software) (Edwards Lifesciences, Irvine, CA, USA) was developed to predict hypotension. We built up the European multicentre, prospective, observational EU HYPROTECT Registry to describe the incidence, duration, and severity of intraoperative hypotension when using HPI-software monitoring in patients having noncardiac surgery.METHODS: We enrolled 749 patients having elective major noncardiac surgery in 12 medical centres in five European countries. Patients were monitored using the HPI-software. We quantified hypotension using the time-weighted average MAP <65 mm Hg (primary endpoint), the proportion of patients with at least one ≥1 min episode of a MAP <65 mm Hg, the number of ≥1 min episodes of a MAP <65 mm Hg, and duration patients spent below a MAP of 65 mm Hg.RESULTS: We included 702 patients in the final analysis. The median time-weighted average MAP <65 mm Hg was 0.03 (0.00-0.20) mm Hg. In addition, 285 patients (41%) had no ≥1 min episode of a MAP <65 mm Hg; 417 patients (59%) had at least one. The median number of ≥1 min episodes of a MAP <65 mm Hg was 1 (0-3). Patients spent a median of 2 (0-9) min below a MAP of 65 mm Hg.CONCLUSIONS: The median time-weighted average MAP <65 mm Hg was very low in patients in this registry. This suggests that using HPI-software monitoring may help reduce the duration and severity of intraoperative hypotension in patients having noncardiac surgery.",
author = "Karim Kouz and {Monge Garc{\'i}a}, {Manuel Ignacio} and Elisabetta Cerutti and Ivana Lisanti and Gaetano Draisci and Luciano Frassanito and Michael Sander and {Ali Akbari}, Amir and Frey, {Ulrich H} and Grundmann, {Carla Davina} and Davies, {Simon James} and Abele Donati and Javier Ripolles-Melchor and Daniel Garc{\'i}a-L{\'o}pez and Benjamin Vojnar and {\'E}tienne Gayat and Eric Noll and Peter Bramlage and Bernd Saugel",
note = "{\textcopyright} 2023 The Author(s).",
year = "2023",
month = jun,
doi = "10.1016/j.bjao.2023.100140",
language = "English",
volume = "6",
pages = "100140",
journal = "BJA Open",
issn = "2772-6096",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery - a European multicentre prospective observational registry (EU HYPROTECT)

AU - Kouz, Karim

AU - Monge García, Manuel Ignacio

AU - Cerutti, Elisabetta

AU - Lisanti, Ivana

AU - Draisci, Gaetano

AU - Frassanito, Luciano

AU - Sander, Michael

AU - Ali Akbari, Amir

AU - Frey, Ulrich H

AU - Grundmann, Carla Davina

AU - Davies, Simon James

AU - Donati, Abele

AU - Ripolles-Melchor, Javier

AU - García-López, Daniel

AU - Vojnar, Benjamin

AU - Gayat, Étienne

AU - Noll, Eric

AU - Bramlage, Peter

AU - Saugel, Bernd

N1 - © 2023 The Author(s).

PY - 2023/6

Y1 - 2023/6

N2 - BACKGROUND: Intraoperative hypotension is associated with organ injury. Current intraoperative arterial pressure management is mainly reactive. Predictive haemodynamic monitoring may help clinicians reduce intraoperative hypotension. The Acumen™ Hypotension Prediction Index software (HPI-software) (Edwards Lifesciences, Irvine, CA, USA) was developed to predict hypotension. We built up the European multicentre, prospective, observational EU HYPROTECT Registry to describe the incidence, duration, and severity of intraoperative hypotension when using HPI-software monitoring in patients having noncardiac surgery.METHODS: We enrolled 749 patients having elective major noncardiac surgery in 12 medical centres in five European countries. Patients were monitored using the HPI-software. We quantified hypotension using the time-weighted average MAP <65 mm Hg (primary endpoint), the proportion of patients with at least one ≥1 min episode of a MAP <65 mm Hg, the number of ≥1 min episodes of a MAP <65 mm Hg, and duration patients spent below a MAP of 65 mm Hg.RESULTS: We included 702 patients in the final analysis. The median time-weighted average MAP <65 mm Hg was 0.03 (0.00-0.20) mm Hg. In addition, 285 patients (41%) had no ≥1 min episode of a MAP <65 mm Hg; 417 patients (59%) had at least one. The median number of ≥1 min episodes of a MAP <65 mm Hg was 1 (0-3). Patients spent a median of 2 (0-9) min below a MAP of 65 mm Hg.CONCLUSIONS: The median time-weighted average MAP <65 mm Hg was very low in patients in this registry. This suggests that using HPI-software monitoring may help reduce the duration and severity of intraoperative hypotension in patients having noncardiac surgery.

AB - BACKGROUND: Intraoperative hypotension is associated with organ injury. Current intraoperative arterial pressure management is mainly reactive. Predictive haemodynamic monitoring may help clinicians reduce intraoperative hypotension. The Acumen™ Hypotension Prediction Index software (HPI-software) (Edwards Lifesciences, Irvine, CA, USA) was developed to predict hypotension. We built up the European multicentre, prospective, observational EU HYPROTECT Registry to describe the incidence, duration, and severity of intraoperative hypotension when using HPI-software monitoring in patients having noncardiac surgery.METHODS: We enrolled 749 patients having elective major noncardiac surgery in 12 medical centres in five European countries. Patients were monitored using the HPI-software. We quantified hypotension using the time-weighted average MAP <65 mm Hg (primary endpoint), the proportion of patients with at least one ≥1 min episode of a MAP <65 mm Hg, the number of ≥1 min episodes of a MAP <65 mm Hg, and duration patients spent below a MAP of 65 mm Hg.RESULTS: We included 702 patients in the final analysis. The median time-weighted average MAP <65 mm Hg was 0.03 (0.00-0.20) mm Hg. In addition, 285 patients (41%) had no ≥1 min episode of a MAP <65 mm Hg; 417 patients (59%) had at least one. The median number of ≥1 min episodes of a MAP <65 mm Hg was 1 (0-3). Patients spent a median of 2 (0-9) min below a MAP of 65 mm Hg.CONCLUSIONS: The median time-weighted average MAP <65 mm Hg was very low in patients in this registry. This suggests that using HPI-software monitoring may help reduce the duration and severity of intraoperative hypotension in patients having noncardiac surgery.

U2 - 10.1016/j.bjao.2023.100140

DO - 10.1016/j.bjao.2023.100140

M3 - SCORING: Journal article

C2 - 37588176

VL - 6

SP - 100140

JO - BJA Open

JF - BJA Open

SN - 2772-6096

ER -