Intraokularer Pseudotumor bei einem Aids-Patienten. Blockexzision, Differentialdiagnose, Histologie
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Intraokularer Pseudotumor bei einem Aids-Patienten. Blockexzision, Differentialdiagnose, Histologie. / Bialasiewicz, A A; Knospe, V; Schäfer, H; Hassenstein, A; Richard, G.
in: OPHTHALMOLOGE, Jahrgang 95, Nr. 4, 01.04.1998, S. 229-32.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Intraokularer Pseudotumor bei einem Aids-Patienten. Blockexzision, Differentialdiagnose, Histologie
AU - Bialasiewicz, A A
AU - Knospe, V
AU - Schäfer, H
AU - Hassenstein, A
AU - Richard, G
PY - 1998/4/1
Y1 - 1998/4/1
N2 - BACKGROUND: Intraocular pseudotumors are a rare event in Aids patients and often pose diagnostic problems.CASE REPORT: A 37-year-old patient who had had HIV seroconversion for 7 years was seen to developed progressively growing, multiple, disseminated, subretinal lesions OD > OS, accompanied by exudative retinal detachment and iritis. Since all etiological laboratory diagnostic efforts to detect an infectious, noninfectious and neoplastic systemic lesion failed, a diagnostic and curative therapeutic chorioretinal excisional biopsy specimen of the largest of the tumors (3 x 3 x 2 mm) was taken. The histological work-up demonstrated granulation tissue similar to an intraocular pseudotumor without signs of infection, malignancy or reactive lymphoid hyperplasia. This finding resulted in systemic corticosteroid treatment with complete resolution of the lesions in both eyes and no recurrences.CONCLUSIONS: An invasive diagnostic procedure in patients suffering from lesions of unknown cause resulting in the institution of an appropriate medical treatment may be beneficial for the integrity and vision of the respective eye.
AB - BACKGROUND: Intraocular pseudotumors are a rare event in Aids patients and often pose diagnostic problems.CASE REPORT: A 37-year-old patient who had had HIV seroconversion for 7 years was seen to developed progressively growing, multiple, disseminated, subretinal lesions OD > OS, accompanied by exudative retinal detachment and iritis. Since all etiological laboratory diagnostic efforts to detect an infectious, noninfectious and neoplastic systemic lesion failed, a diagnostic and curative therapeutic chorioretinal excisional biopsy specimen of the largest of the tumors (3 x 3 x 2 mm) was taken. The histological work-up demonstrated granulation tissue similar to an intraocular pseudotumor without signs of infection, malignancy or reactive lymphoid hyperplasia. This finding resulted in systemic corticosteroid treatment with complete resolution of the lesions in both eyes and no recurrences.CONCLUSIONS: An invasive diagnostic procedure in patients suffering from lesions of unknown cause resulting in the institution of an appropriate medical treatment may be beneficial for the integrity and vision of the respective eye.
KW - Adult
KW - Biopsy
KW - Diagnosis, Differential
KW - HIV Infections
KW - Humans
KW - Male
KW - Orbital Pseudotumor
KW - Retina
KW - Retinal Diseases
M3 - SCORING: Zeitschriftenaufsatz
C2 - 9623259
VL - 95
SP - 229
EP - 232
JO - OPHTHALMOLOGE
JF - OPHTHALMOLOGE
SN - 0941-293X
IS - 4
ER -